Objective To systematically evaluate the influencing factors for antiretroviral therapy(ART)discontinuation in Chinese human immunodeficiency virus(HIV)/acquired immuno deficiency syn-drome(AIDS)patients.Methods A computer-based search was conducted in PubMed,Web of Science,Em-base,The Cochrane Library,CNKI,Wanfang,VIP,and China Biology Medicine(CBM)databases for studies on influencing factors of ART discontinuation in Chinese HIV/AIDS patients from the establishment of the databases to August 2024.Meta-analysis was performed on the included studies by using Stata16.0.Results A total of 17 studies were included.Meta-analysis showed that the following factors were associated with ART discontinuation:male gender(OR=1.301,95%CI:1.099-1.540),age≥50 years(OR=1.212,95%CI:1.109-1.324),unmarried/divorced/widowed marital status(OR=1.198,95%CI:1.060-1.354),education level was or below senior high school(OR=1.778,95%CI:1.508-2.096),infection route was in-travenous drug use(OR=2.420,95%CI:1.989-2.945),baseline CD4 cell count>500 cells/μL(OR=1.157,95%CI:1.020-1.313),tuberculosis co-infection before ART(OR=1.559,95%CI:1.398-1.739),hepatitis B co-infection before ART(OR=1.554,95%CI:1.305-1.851),AIDS-related symptoms occur be-fore ART(OR=1.245,95%CI:1.148-1.351),time from diagnosis to treatment initiation≥365 days(OR=1.449,95%CI:1.301-1.615),initial treatment regimen containing zidovudine(OR=1.573,95%CI:1.206-2.052),treatment at county-level or lower institutions(OR=1.204,95%CI:1.153-1.257),exist drug adverse reactions(OR=7.043,95%CI:3.142-15.786),and compliance education(OR=0.182,95%CI:0.094-0.352).Conclusion There are multiple factors influencing ART discontinuation in Chinese HIV/AIDS patients.Early identification of individuals at risk of discontinuation and targeted interventions are nec-essary to promote their maintenance of ART.

Drug literacy is one of the important components of health literacy,and in recent years,the research on drug literacy has gradually deepened.The polypharmacy treatment and irrational drug use in the patients with HIV/AIDS has increased the burden of drug use,therefore improving the level of drug literacy is the key to maintain the medication efficacy,drug self-administered and safe medication.This paper summa-rized the definition,current status of assessment tools,influencing factors and interventional measures of drug literacy of HIV/AIDS patients in domestic and foreign research in order to provide reference for the develop-ment of assessment tools for drug literacy of HIV/AIDS patients,improve the level of drug literacy of pa-tients,and promote safe and rational use of drugs.

Objective Meta-analysis was used to evaluate the effect of the solution-focused brief therapy on im-proving the anxiety and depression status of patients with HIV/AIDS.Methods Computer search of PubMed,Embase,Web of Science,Cochrane Library,CINAHL,PsycINFO,Chinese Biomedical Literature Database,China Na-tional Knowledge Infrastructure,Wanfang Database,CQVIP were conducted,and the search time frame was from the establishment of databases until April 9,2023.There were 2 investigators who independently screened the literature according to inclusion and exclusion criteria,extracted data and performed quality evaluation,and performed Meta-analysis using RevMan 5.4 software.Results A total of 11 publications were included,including 9 randomized controlled trials and 2 quasi-experimental studies,with a total of 1 219 patients with HIV/AIDS.Meta-analysis re-sults showed that solution-focused brief therapy reduced anxiety scores(SMD=-1.89;95%CI:-2.79～-0.99,P＜0.001),depression scores(SMD=-2.45;95%CI:-3.51～-1.39,P＜0.001).Subgroup analysis showed that improved anxiety(SMD=-4.16;95%CI:-7.97～-0.35,P＜0.001),depression(SMD=-5.69;95%CI:-11.20～-0.19,P＜0.001)in pregnant HIV/AIDS patients was significantly better than that in ordinary patients.Conclusion Solution-focused brief therapy is effective in improving anxiety and depression levels in patients with HIV/AIDS,and the application of this model in pregnant patients with HIV/AIDS has a more significant improvement effect,but high-quality,multicenter,large-sample clinical trial studies are needed to further confirm this conclusion in the future.

Objective:To explore the effect of cupping therapy on regulating phlegm dampness constitution of elderly patients with hypertension in the community.Methods:From August to November in 2019, 120 elderly patients with phlegm dampness hypertension were randomly divided into control group and intervention group, 60 cases in each. The control group was given traditional Chinese medicine (TCM) health care in the community, and the intervention group was given cupping therapy intervention on this basis, to evaluate the changes of the scores of TCM phlegm wet body mass table, the total score reduction rate of TCM phlegm wet body mass, the conversion rate of TCM phlegm wet body mass, blood pressure, body mass index and waist circumference between the two groups before the intervention, 1 month, 2 months, 3 months after the intervention.Results:Finally, there were 51 cases in the intervention group and 57 cases in the control group. The TCM phlegm dampness constitution sub-scale and total scores of the comparison between groups at four different time points showed that except for the dimension of abdominal hypertrophy, the sub-scale and total scores of TCM phlegm-dampness constitution scale in the two groups were lower than before, and the differences were statistically significant ( F values were 3.450-94.995, P<0.05). The total score reduction rate of phlegm dampness constitution in the intervention group was 0.17 ± 0.10, higher than that in the control group (0.12 ± 0.09), and the difference was statistically significant ( t value was - 2.773, P < 0.05). The transformation rate of phlegm-dampness constitution was 47.1% (24/51) in the intervention group, which was higher than that in the control group (33.3%,19/57). The value of systolic blood pressure was lower in the intervention group [(135.10±2.64) mmHg,1 mmHg=0.133 kPa] than that in the control group [(138.88±2.42) mmHg] after 2 months of intervention, and the difference was statistically significant ( F value was 6.586, P<0.05). The value of diastolic blood pressure was lower in the intervention group [(80.75±3.03) mmHg] than that in the control group [(78.14±3.43) mmHg] after 3 months of intervention, and the difference was statistically significant ( F value was 6.758, P<0.05). Conclusions:On the basis of TCM physical nursing in the community, the effect of cupping therapy on reducing the score of phlegm and dampness physical fitness of elderly hypertension patients in the community, promoting the transformation of phlegm and dampness physical fitness of elderly hypertension patients in the community, and reducing the blood pressure level of elderly hypertension patients in the community is better than that of TCM physical nursing in the community, which is worth being promoted in the community.

How to improve the clinical ability of nursing undergraduates has become the focus of attention in the reform of nursing education at home and abroad. This article reviews the evaluation development, evaluation methods and the application of undergraduates' clinical ability in nursing education, as well as the advantages and disadvantages in the application process by retrieving relevant domestic and foreign literature, and makes recommendations for the evaluation and development of clinical ability of nursing undergraduates. This article aims at providing an objective basis for objectively evaluating the clinical ability of students in the training of nursing talents in higher nursing education, so as to further improve the evaluation system in higher nursing education.

In recent years, the incidence of sleep disorders is increasing gradually, and sleep disorder has become a common and frequently-occurring disease in community. While drugs bring a series of side effects, non-pharmacological therapy has become a hotspot in sleep quality study field. It is found that"Gua sha" therapy has a significant effect in improving sleep quality as one of the traditional Chinese medicine (TCM) care techniques by literature review. This paper summarized the current situation and analyzed the deficiencies of "Gua sha" in sleep improvement basing on the theoretical foundation of Chinese medicine and biological mechanism, so as to provide references for future research and provide guidance for promoting the application of "Gua sha" therapy in community.

Objective:To explore the correlation between medication adherence and quality of life (QOL) in aged pa‐tients with hypertension from communities .Methods :Chinese questionnaire of quality of life in patients with cardi‐ovascular disease (CQQC) and Morisky medication adherence scale were used to investigate and analyze 197 aged pa‐tients with hypertension from communities .Results:Total score of CQQC was (78.69 ± 9.36) scores in the 197 aged patients with hypertension from communities .In which ,77 cases (39.09% ) possessed good medication adherence , and 120 cases ( (60. 91% )) with poor adherence to medication . Compared with those with poor adherence to medi‐cation,therewassignificantriseintotalscoreofCQQC [(75.73±8.52)scoresvs.(83.31±8.76)scores ,P<0.01] .Pearson correlation analysis indicated that QOL was significant positively correlated with medication adher‐ence (r=0.397 , P<0.01) .Conclusion:Community health staff should pay attention to influencing factors of med‐ication adherence in aged patients with hypertension ,take individualized and targeted interventional measures to im‐prove their adherence to medicationand quality of life .

Objective To investigate current status and correlation between medication compliance and social relational quality of elderly patients with hypertension in community and to provide reference for intervention on chronic disease in community.Methods Totally 300 elderly patients with hypertension in Beihu Nanmian Community,Xixiangtang District,were recruited by convenience sampling method. Social relational quality scale (SRQS) and Morisky questionnaire were applied to investigate their social relational quality and medication compliance.Results The score of social relational quality was (48.45±5.48),and the score of medication compliance was (10.45±2.71). There was a significant difference in the score of medication compliance among patients with different education level and monthly income (P<0.05). Education level,monthly income,and social relational quality were positively correlated with medication compliance of community elderly patients with hypertension (β'=0.349,0.376,0.411;P<0.05).Conclusions Elderly patients with hypertension in community with higher social relational quality tend to have a better medication compliance.

Objective:To investigate the impact of humanistic spirit cultivation on nursing students' ethics cog-nition. Method:Total 364 internship nursing students in 2010 were taken as the control group with the routine clini-cal teaching method, 381 in 2014 as the experimental group, not only a routine clinical teaching method but also to increase of their humanistic spirit culture. Results:Humanity spirit cultivation before and after practice nursing students in medical security system cognition difference is not significant, but in medical optimization, the patients right of informed consent, the life value differences of cognitive and ethical cognitive dimension score was statisti-cally significant ( P<0 . 05 ) . Conclusions:Humanistic spirit culture promote the practice of nursing students to raise the level of moral cognition foundation for humanity quality education and nursing ethics education, should further strengthen the diversification of internship training nursing students humanistic spirit.

Objective To study heath-related quality of life in patients undergoing successful percutaneous coronary intervention(PCI)six months after operation.Methods 172 hospitalized patients who met the inclusion criteria were selected from July 2009 to May 2010.They were divided into the neversmoking group,ever-smoking group and the current-smoking group.The Seattle Angina Questionnaire (SAQ) and the Short Form-36 (SF-36)were used to assess the quality of life at baseline and 6 months after intervention.The comparison between groups and self-control comparison within groups were carried out according to each dimension of the questionnaire.Results SF-36 and SAQ score showed no significant difference 24h before the operation and 6 months after the operation between three groups.Patients who had never smoked and who were current smokers acquired higher scores in many dimensions of the questionnaire compared with those before operation,while patients who were former smokers reported reverse resuits.Conclusions There is no sufficient evidence proving that smoking status influences quality of life of patients after PCI,that is to say,it can not be considered that quality of life of smoking patients is lower than that of ever-smoking patients or never-smoking patients,since in this research,quality of life of eversmoking patients decreased after PCI.