Objective:To investigate the association of psychological resilience with character strengths and emotional symptoms in medical students from the perspective of positive psychology.Methods:From December 2020 to January 2021, the convenience sampling method was used to select 284 medical students in a medical university, and a questionnaire survey was conducted using Resilience Scale for Chinese Adolescents (RSCA), Chinese Virtues Questionnaire (CVQ-96), and Depression Anxiety Stress Scale (DASS-21). SPSS 25.0 was used to perform the two-independent-samples t test or the one-way analysis of variance, and the Spearman correlation analysis was performed for all data. Results:For these medical students, the scores of psychological resilience and character strengths were 92.16±13.00 and 360.44±62.66, respectively. The top five strengths were sincerity, fairness, love, leadership, and teamwork, while the bottom five strengths were self-regulation, learning, modesty, perspective, and creativity. The positive rates of stress, anxiety, and depression were 41.90% (119/284), 60.21% (171/284), and 52.46% (149/284), respectively. The difference analysis showed that there was a significant difference in the score of psychological resilience between groups based on sex, whether to participate in class activities, and whether to talk to others when facing difficulties ( P<0.05); there was a significant difference in the score of character strengths between groups based on whether to be a class leader, whether to participate in class activities, and whether to talk to others when facing difficulties ( P<0.05); there were significant differences in the scores of stress, anxiety, and depression between groups based on sex and whether to be the only child of the family ( P<0.05). The correlation analysis showed that psychological resilience was positively correlated with character strengths and was negatively correlated with emotional symptoms. Conclusions:The medical students with higher psychological resilience tend to have outstanding character strengths and a lower positive rate of emotional symptoms.