1.Thoughts on research and development of female contraceptives from the perspective of pharmaceutics
Jia ZENG ; Fang LI ; Jianxing CHEN ; Liangkang CHEN ; Linglin FENG
Chinese Journal of Reproduction and Contraception 2021;41(8):731-738
In recent years, the world community has aroused interest in family planning as a prioritized strategy to improve maternal health, and China has also incorporated reproductive health into its national development strategies. Safe and effective contraceptive methods for women of childbearing age to prevent unwanted pregnancy and reduce abortion, is an important measure to improve their reproductive health. This paper firstly summarizes the global market demand for female contraceptive products. Then, starting from the early research and development (R&D) stages such as raw materials selection, pre-formulation and formulation investigations, this paper discusses the R&D thoughts of contraceptives including long-acting biodegradable implants and microsphere injections. Finally, we review the application prospects of 3D printing, computer simulation and artificial intelligence in this field. Interdisciplinary integration of pharmaceutical and computer science is expected to inspire and change the development mode of traditional preparations, as well as to help accelerate the industrialization of contraceptives.
2.Thoughts on research and development of female contraceptives from the perspective of pharmaceutics
Jia ZENG ; Fang LI ; Jianxing CHEN ; Liangkang CHEN ; Linglin FENG
Chinese Journal of Reproduction and Contraception 2021;41(8):731-738
In recent years, the world community has aroused interest in family planning as a prioritized strategy to improve maternal health, and China has also incorporated reproductive health into its national development strategies. Safe and effective contraceptive methods for women of childbearing age to prevent unwanted pregnancy and reduce abortion, is an important measure to improve their reproductive health. This paper firstly summarizes the global market demand for female contraceptive products. Then, starting from the early research and development (R&D) stages such as raw materials selection, pre-formulation and formulation investigations, this paper discusses the R&D thoughts of contraceptives including long-acting biodegradable implants and microsphere injections. Finally, we review the application prospects of 3D printing, computer simulation and artificial intelligence in this field. Interdisciplinary integration of pharmaceutical and computer science is expected to inspire and change the development mode of traditional preparations, as well as to help accelerate the industrialization of contraceptives.
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