1.Qualitative research on post competence of nursing staff in large surface ships
Anhua QIAO ; Xiaojia HUANG ; Fei PENG ; Liandi GAO ; Jingjing WANG ; Xiedong SHEN
Journal of Navy Medicine 2024;45(2):125-129
Objective To explore the characteristic elements of post competence of nursing staff in large surface ships medical support,and to provide reference for the special training within military hospital and training for dispatched nursing staff.Methods Sixteen medical people who have carried out the large surface ship medical support were selected as research objects using the purposive sampling method.One-to-one semi-structured interviews were performed.The Colaizzi phenomenological analysis was used to carefully sort out and analyze the obtained data and summarize the theme.Results The core competency characteristics of nursing staff during the large surface ships medical support were extracted,including four elements:professional knowledge of common diseases on ships,professional nursing skills on ships,rescue professional ability in ships,and military quality.Conclusion It is essential to construct nursing staff training,system based on the core competencies of large surface ships medical support,and to reserve military nursing talents in daily training,so as to complete medical support tasks with high standards.
2.Protective effect of icariin on osteoporosis in ovariectomized rats and its mechanism
Tongtong ZHU ; Liandi HUANG ; Junwei LI ; Benzheng ZHAO ; Mengyang JIANG ; Na LI ; Fan ZHAO
Journal of Jilin University(Medicine Edition) 2016;42(5):915-919
Objective:To observe the effect of icariin on the osteoporosis of the ovariectomized rats,and to explore the mechanism.Methods:Fifty female rats aged 6 months were randomly divided into sham operation group, model group,positive drug group,low dose of icariin group and high dose of icariin group (n= 10).The rats in positive drug group were given with 1 mg· kg-1 nilestriol every week;the rats in low and high doses of icariin groups were given with 50 and 100 mg · kg-1 icariin every day.The bilateral ovaries of rats were excised by operation to establish the osteoporosis models.2 weeks after operation,the rats were treated with icariin for 12 weeks,and then they were sacrificed by drawing blood from abdominal aorta under anesthesia condion.The bone mineral density (BMD),serum biochemical indicators,bone histomorphology and the expressions of apoptosis-related proteins were detected.Results:Compared with sham operation group,the BMD of the rats in model group was decreased (P <0.01),the serum calcium level was decreased (P <0.05),and the serum phosphorus level was increased (P <0.05),and the serum BGP,ALP,NO and NOS levels were significantly decreased (P <0.05 or P <0.01).Compared with model group,the BMD of the rats in positive drug group and high dose of icariin group were obviously increased (P < 0.01 ), the serum calcium levels were increased, the phosphorus levels were decreased (P <0.05),and the BGP and ALP levels were increased significantly (P < 0.05 ). Compared with control group,the cortical in model group was thinned,the width of bone trabecula was reduced,the Bax and Caspase-3 expression levels in bone tissue were increased,and the Bcl-2 expression level was decreased.Compared with model group,the cortical in icariin group was thicked,the width of bone trabecula was increased,the Bax and Caspase-3 expression levels were decreased,and the Bcl-2 expression level was increased (P <0.05 or P <0.01). Conclusion:Icariin can protect the osteoporosis of ovariectomized rats,the function may be related to the inhibition of apoptosis.

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