1.In vitro heat insulation efficacy of 5% dextrose versus 0.9% saline during radiofrequency ablation
Yanping MA ; Jinfen WANG ; Tao WU ; Bowen ZHENG ; Tinghui YIN ; Yufan LIAN ; Jie REN
Ultrasonography 2024;43(5):376-383
Purpose:
This study compared the efficacy of heat insulation between 5% dextrose and 0.9% saline in radiofrequency ablation (RFA). Accordingly, temperature variations and maximum temperatures were assessed at identical distances and heat field distributions.
Methods:
Cubes of porcine liver tissue, measuring 10 mm across, were selected to precisely align the ablation boundary with the tissue boundary. An 18-gauge electrode with a 7-mm tip was inserted into each cube (10 per group) in a stainless-steel cup containing 40 mL of 5% dextrose or 0.9% saline. Fixed ablation was performed for 3 minutes using continuous mode at 30 W, simulating the typical thermal environment during thyroid RFA. Real-time temperature measurements were recorded by sensors positioned 0, 1, 3, and 5 mm from the cube’s edge. A comparative analysis was conducted to assess the maximum temperature, temperature variation, and duration of temperatures exceeding 42℃.
Results:
In both groups, the temperature curve declined with increasing distance from the edge of the ablated tissue. However, 0.9% saline exhibited higher maximum temperatures at 1, 3, and 5 mm compared to 5% dextrose (1 mm: 44.55°C±5.25°C vs. 34.68°C±3.07°C; 3 mm: 39.64°C±2.53°C vs. 29.22°C±2.21°C; 5 mm: 38.86°C±2.14°C vs. 28.74°C±2.51°C; all P<0.001). Considering a nerve injury threshold of 42°C, the 0.9% saline also displayed a greater proportion of samples reaching this temperature and a longer duration of temperatures exceeding it (P<0.05).
Conclusion
The heat insulation efficacy of 5% dextrose at 1-5 mm exceeds that of 0.9% saline at identical distances and in a common thermal environment during thyroid RFA.
2.In vitro heat insulation efficacy of 5% dextrose versus 0.9% saline during radiofrequency ablation
Yanping MA ; Jinfen WANG ; Tao WU ; Bowen ZHENG ; Tinghui YIN ; Yufan LIAN ; Jie REN
Ultrasonography 2024;43(5):376-383
Purpose:
This study compared the efficacy of heat insulation between 5% dextrose and 0.9% saline in radiofrequency ablation (RFA). Accordingly, temperature variations and maximum temperatures were assessed at identical distances and heat field distributions.
Methods:
Cubes of porcine liver tissue, measuring 10 mm across, were selected to precisely align the ablation boundary with the tissue boundary. An 18-gauge electrode with a 7-mm tip was inserted into each cube (10 per group) in a stainless-steel cup containing 40 mL of 5% dextrose or 0.9% saline. Fixed ablation was performed for 3 minutes using continuous mode at 30 W, simulating the typical thermal environment during thyroid RFA. Real-time temperature measurements were recorded by sensors positioned 0, 1, 3, and 5 mm from the cube’s edge. A comparative analysis was conducted to assess the maximum temperature, temperature variation, and duration of temperatures exceeding 42℃.
Results:
In both groups, the temperature curve declined with increasing distance from the edge of the ablated tissue. However, 0.9% saline exhibited higher maximum temperatures at 1, 3, and 5 mm compared to 5% dextrose (1 mm: 44.55°C±5.25°C vs. 34.68°C±3.07°C; 3 mm: 39.64°C±2.53°C vs. 29.22°C±2.21°C; 5 mm: 38.86°C±2.14°C vs. 28.74°C±2.51°C; all P<0.001). Considering a nerve injury threshold of 42°C, the 0.9% saline also displayed a greater proportion of samples reaching this temperature and a longer duration of temperatures exceeding it (P<0.05).
Conclusion
The heat insulation efficacy of 5% dextrose at 1-5 mm exceeds that of 0.9% saline at identical distances and in a common thermal environment during thyroid RFA.
3.In vitro heat insulation efficacy of 5% dextrose versus 0.9% saline during radiofrequency ablation
Yanping MA ; Jinfen WANG ; Tao WU ; Bowen ZHENG ; Tinghui YIN ; Yufan LIAN ; Jie REN
Ultrasonography 2024;43(5):376-383
Purpose:
This study compared the efficacy of heat insulation between 5% dextrose and 0.9% saline in radiofrequency ablation (RFA). Accordingly, temperature variations and maximum temperatures were assessed at identical distances and heat field distributions.
Methods:
Cubes of porcine liver tissue, measuring 10 mm across, were selected to precisely align the ablation boundary with the tissue boundary. An 18-gauge electrode with a 7-mm tip was inserted into each cube (10 per group) in a stainless-steel cup containing 40 mL of 5% dextrose or 0.9% saline. Fixed ablation was performed for 3 minutes using continuous mode at 30 W, simulating the typical thermal environment during thyroid RFA. Real-time temperature measurements were recorded by sensors positioned 0, 1, 3, and 5 mm from the cube’s edge. A comparative analysis was conducted to assess the maximum temperature, temperature variation, and duration of temperatures exceeding 42℃.
Results:
In both groups, the temperature curve declined with increasing distance from the edge of the ablated tissue. However, 0.9% saline exhibited higher maximum temperatures at 1, 3, and 5 mm compared to 5% dextrose (1 mm: 44.55°C±5.25°C vs. 34.68°C±3.07°C; 3 mm: 39.64°C±2.53°C vs. 29.22°C±2.21°C; 5 mm: 38.86°C±2.14°C vs. 28.74°C±2.51°C; all P<0.001). Considering a nerve injury threshold of 42°C, the 0.9% saline also displayed a greater proportion of samples reaching this temperature and a longer duration of temperatures exceeding it (P<0.05).
Conclusion
The heat insulation efficacy of 5% dextrose at 1-5 mm exceeds that of 0.9% saline at identical distances and in a common thermal environment during thyroid RFA.
4.In vitro heat insulation efficacy of 5% dextrose versus 0.9% saline during radiofrequency ablation
Yanping MA ; Jinfen WANG ; Tao WU ; Bowen ZHENG ; Tinghui YIN ; Yufan LIAN ; Jie REN
Ultrasonography 2024;43(5):376-383
Purpose:
This study compared the efficacy of heat insulation between 5% dextrose and 0.9% saline in radiofrequency ablation (RFA). Accordingly, temperature variations and maximum temperatures were assessed at identical distances and heat field distributions.
Methods:
Cubes of porcine liver tissue, measuring 10 mm across, were selected to precisely align the ablation boundary with the tissue boundary. An 18-gauge electrode with a 7-mm tip was inserted into each cube (10 per group) in a stainless-steel cup containing 40 mL of 5% dextrose or 0.9% saline. Fixed ablation was performed for 3 minutes using continuous mode at 30 W, simulating the typical thermal environment during thyroid RFA. Real-time temperature measurements were recorded by sensors positioned 0, 1, 3, and 5 mm from the cube’s edge. A comparative analysis was conducted to assess the maximum temperature, temperature variation, and duration of temperatures exceeding 42℃.
Results:
In both groups, the temperature curve declined with increasing distance from the edge of the ablated tissue. However, 0.9% saline exhibited higher maximum temperatures at 1, 3, and 5 mm compared to 5% dextrose (1 mm: 44.55°C±5.25°C vs. 34.68°C±3.07°C; 3 mm: 39.64°C±2.53°C vs. 29.22°C±2.21°C; 5 mm: 38.86°C±2.14°C vs. 28.74°C±2.51°C; all P<0.001). Considering a nerve injury threshold of 42°C, the 0.9% saline also displayed a greater proportion of samples reaching this temperature and a longer duration of temperatures exceeding it (P<0.05).
Conclusion
The heat insulation efficacy of 5% dextrose at 1-5 mm exceeds that of 0.9% saline at identical distances and in a common thermal environment during thyroid RFA.
5.In vitro heat insulation efficacy of 5% dextrose versus 0.9% saline during radiofrequency ablation
Yanping MA ; Jinfen WANG ; Tao WU ; Bowen ZHENG ; Tinghui YIN ; Yufan LIAN ; Jie REN
Ultrasonography 2024;43(5):376-383
Purpose:
This study compared the efficacy of heat insulation between 5% dextrose and 0.9% saline in radiofrequency ablation (RFA). Accordingly, temperature variations and maximum temperatures were assessed at identical distances and heat field distributions.
Methods:
Cubes of porcine liver tissue, measuring 10 mm across, were selected to precisely align the ablation boundary with the tissue boundary. An 18-gauge electrode with a 7-mm tip was inserted into each cube (10 per group) in a stainless-steel cup containing 40 mL of 5% dextrose or 0.9% saline. Fixed ablation was performed for 3 minutes using continuous mode at 30 W, simulating the typical thermal environment during thyroid RFA. Real-time temperature measurements were recorded by sensors positioned 0, 1, 3, and 5 mm from the cube’s edge. A comparative analysis was conducted to assess the maximum temperature, temperature variation, and duration of temperatures exceeding 42℃.
Results:
In both groups, the temperature curve declined with increasing distance from the edge of the ablated tissue. However, 0.9% saline exhibited higher maximum temperatures at 1, 3, and 5 mm compared to 5% dextrose (1 mm: 44.55°C±5.25°C vs. 34.68°C±3.07°C; 3 mm: 39.64°C±2.53°C vs. 29.22°C±2.21°C; 5 mm: 38.86°C±2.14°C vs. 28.74°C±2.51°C; all P<0.001). Considering a nerve injury threshold of 42°C, the 0.9% saline also displayed a greater proportion of samples reaching this temperature and a longer duration of temperatures exceeding it (P<0.05).
Conclusion
The heat insulation efficacy of 5% dextrose at 1-5 mm exceeds that of 0.9% saline at identical distances and in a common thermal environment during thyroid RFA.
8. Nutritional physical indexes, obesity status and their warning effect on hypertension among Blang, Deang and Va ethnic groups in Yunnan
Zi-Shan WANG ; Yu CHENG ; Xing-Hua ZHANG ; Ke-Li YU ; Lian-Bin ZHENG ; Xing-Hua ZHANG ; Ke-Li YU ; Lian-Bin ZHENG ; Fei XU ; Yu CHENG
Acta Anatomica Sinica 2023;54(6):730-737
Objective To analyze the nutritional level, obesity status and the prevalence of frypertension in Blang, Deang and Va ethnic groups in Yunnan, to explore the relationship among nutritional physical index, obesity indicators and blood pressure, and use the cutoff value of related indicators to warn frypertension. Methods This paper was based on a statistical analysis of the 7 nutritional pfrysical indexes, 5 types of obesity status and frypertension status of 766 Blang, 570 Deang and 565 Va. Results We found that the nutritional pfrysique index of man)' items (4 items for men and 4 items for women) of Blang was significantly higher than that of Deang and Va (P<0. 05), the Erismann' s index and Pelidisi' s index of Deang female were significantly higher than those of Blang female and Va female (P<0. 05). The differences in the obesity rates determined by the three obesity determination indexes of waist circumference (WC), waist-to-hip ratio (WHR) and percent of bod)' fat (PBF) were statistically significant among the three ethnic groups (P < 0. 05), and the obesity rates determined by the three indexes of bod)' mass index (BMI), body adiposity index (BAI) and PBF were all the highest in the Blang, and the central obesity rates determined by the two indexes of WC and WHR were all the highest in Va. The rank of the prevalence of hypertension was Va > Blang > Deang and the difference was statistically significant (P<0. 05). Conclusion Pelidisi' s index, WHR, and PBF all have good early warning effects on frypertension in all three ethnic groups.
9.An analysis on senior pupil's tobacco use and exposure in Shandong province in 2012 and 2019.
Xia WEI ; Yan LENG ; Tong SUN ; Jia Xiang HOU ; Lian Sen WANG ; Ting LIU ; Rui LI ; Pei Jing ZHOU ; Yong Juan LIU ; Dian Min KANG
Chinese Journal of Epidemiology 2022;43(5):681-685
Objective: To analyze the changes in tobacco use and exposure in primary school students in Shandong province in 2012 and 2019. Methods: A multi-stage stratified cluster random sampling method was used in the survey. In 2012 and 2019, 5 861 and 4 021 students from 3 different cities of Shandong province were selected as the study population. The questionnaire was filled anonymously by the subjects. χ2 test was conducted to compare the difference of groups. Results: In 2012 and 2019, the rate of attempting smoking among pupils under this study in Shandong province were 6.0%and 6.3%, respectively, while the current smoking rate were 1.2%and 2.3%, respectively. The sex ratio of male and female students attempting to smoke was 2.56∶1 in 2012 and 1.31∶1 in 2019. The sex ratio of current smoking rate was 2.43∶1 and 2.00∶1, respectively in 2012 and in 2019. The rate of tobacco exposure in the public places was 50.5%and 41.4%, respectively. The rate of tobacco exposure in family was 49.7% and 46.4%, respectively. Two rates of tobacco exposure decreased, but the reduction in family (3.3%) was far less than that in public places (9.1%). In 2019, the rate of tobacco exposure in family was higher than that in public places. Conclusions: The tobacco exposure rate declined in senior pupils in Shandong province. However, the situation is still grim for the current smoking rate, growth trend of girls tobacco use, and tobacco exposure in family.
Cities
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Environment
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Female
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Humans
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Male
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Prevalence
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Students
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Surveys and Questionnaires
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Tobacco Smoke Pollution
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Tobacco Use/epidemiology*
10.Analysis of Daily Steps Threshold Corresponding to Pregnancy Physical Activity Recommendation Based on Accelerometer
Han-qing CHEN ; Casper J.P. ZHANG ; Wai-kit MING ; Zi-lian WANG
Journal of Sun Yat-sen University(Medical Sciences) 2022;43(5):788-794
ObjectivesThis study aims to use accelerometer to objectively evaluate daily physical activity (PA) and steps of single pregnant women, and preliminarily explore the threshold of daily steps in line with the recommended PA during pregnancy, so as to provide PA guidance for pregnant women. MethodsWomen with singleton pregnancies who had prenatal examination in the the First Affiliated Hospital of Sun Yat-sen University from April 2018 to September 2019 continuously wore an accelerometer for 7 days for three times to measure daily PA. A total of 178 cases were included in this study with the average age 30.0 ± 3.0 years. Data were downloaded by supporting software, and the relationship between daily steps and PA (total PA, light PA and moderate PA) were analyzed by linear correlation analysis. Linear regression analysis and receiver operator characteristic curve (ROC) analysis were both used to explore the threshold steps corresponding to the physical activity recommendation. ResultsThere was no difference in daily total PA, light PA and sedentary behavior time during the three trimesters (P > 0.05). But the moderate PA decreased with the pregnancy stages increased (25.1±16.1 vs. 23.6±16.5 vs. 21.5±16.1,min/d, P = 0.001). There was a positive correlation between total PA and daily steps during the three trimesters (The correlation coefficients r of the early pregnancy, mid pregnancy and late pregnancy were 0.87, 0.83 and 0.86, respectively, P < 0.001); and there was a positive correlation with light PA (r of the three trimesters were 0.79, 0.72 and 0.77, respectively, P < 0.001). The relationship between moderate PA and daily steps during the three trimesters also had similar results (r of the three trimesters were 0.62, 0.53 and 0.55, respectively, P < 0.001). The thresholds of daily steps to reach the recommended PA during pregnancy in the early, mid and late pregnancy were 10 925 steps, 11 372 steps and 11 170 steps, respectively. According to ROC analysis, the thresholds of daily steps in the three trimesters were 10 856 steps, 10 480 steps and 9 819 steps, respectively, and the areas under the curve were 0.81, 0.73 and 0.74, respectively (P < 0.001). ConclusionsThe daily physical activity is mainly walking during pregnancy. Based on accelerometer evaluation, daily walking 9 800 to 11 500 steps could reach the physical activity recommendation during pregnancy.

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