1.Association between blood pressure, inflammation and spirometry parameters in chronic obstructive pulmonary disease.
Sulhattin ARSLAN ; Gürsel YILDIZ ; Levent ÖZDEMIR ; Erdal KAYSOYDU ; Bülent ÖZDEMIR
The Korean Journal of Internal Medicine 2019;34(1):108-115
BACKGROUND/AIMS: Many systems including the cardiovascular system (ischemic heart diseases, heart failure, and hypertension) may act as comorbidities that can be seen during the course of chronic obstructive pulmonary disease (COPD). Comorbidities affect the severity and prognosis of COPD negatively. Nearly 25% of patients with COPD die due to cardiovascular diseases. In this study, we aimed to evaluate the relationship between the blood pressure, inflammation, hypoxia, hypercapnia, and the severity of airway obstruction. METHODS: We included 75 COPD patients in the study with 45 control cases. We evaluated age, sex, body mass index, smoking history, C-reactive protein levels, 24-hour ambulatory blood pressure Holter monitoring, arterial blood gas, and respiratory function tests of the patient and the control groups. RESULTS: In COPD patients, the night time systolic, diastolic blood pressures and pulse per minute and the mean blood pressures readings were significantly elevated compared to the control group (p < 0.05). In the correlation analysis, night time systolic pressure was associated with all the parameters except forced expiratory volume in 1 second (FEV₁%). Diastolic blood pressure was associated with pH and HCO₃ levels. The mean night time, day time pulse pressures and 24-hour pulse per minute values were also associated with all the parameters except FEV₁%. CONCLUSIONS: In this study we found that parameters of systolic and diastolic blood pressures and pulse pressures were significantly elevated in COPD patients compared to the control groups. Blood pressure was associated blood gas parameters and inflammation parameters in COPD patients. This, in turn, may cause understanding of the pathophysiology of COPD and its complications.
Airway Obstruction
;
Anoxia
;
Blood Pressure*
;
Body Mass Index
;
C-Reactive Protein
;
Cardiovascular Diseases
;
Cardiovascular System
;
Comorbidity
;
Electrocardiography, Ambulatory
;
Forced Expiratory Volume
;
Heart Diseases
;
Heart Failure
;
Humans
;
Hydrogen-Ion Concentration
;
Hypercapnia
;
Inflammation*
;
Prognosis
;
Pulmonary Disease, Chronic Obstructive*
;
Reading
;
Respiratory Function Tests
;
Smoke
;
Smoking
;
Spirometry*
2.Anaphylaxis due to ruptured pulmonary hydatid cyst in a 13-year-old boy
Ahmet ÖZDEMIR ; Sefika Elmas BOZDEMIR ; Demet AKBIYIK ; Ghania DAAR ; Sabriye KORKUT ; Levent KORKMAZ ; Osman BAŞTUĞ
Asia Pacific Allergy 2015;5(2):128-131
Hydatid cyst, a common disease in the world, is usually transmitted to humans through dog feces. Hydatid cyst is caused by Echinococcus granulosus. Diagnostic interventions for hydatid cyst include physical examination and chest x-ray tomography. Although the treatment options of hydatid cyst vary according to the clinical findings of the patients, the primary treatment may be considered as surgery. We herein reported the case of a child hospitalized due to pneumonia who developed anaphylaxis as a result of the rupture of a pulmonary hydatid cyst.
Adolescent
;
Anaphylaxis
;
Animals
;
Child
;
Dogs
;
Echinococcosis
;
Echinococcosis, Pulmonary
;
Echinococcus granulosus
;
Eosinophils
;
Feces
;
Humans
;
Male
;
Physical Examination
;
Pneumonia
;
Rupture
;
Thorax
;
Tomography, X-Ray

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