Pan-vascular diseases are a group of diseases involving the systemic vascular system， with vascular lesions （especially atherosclerosis） as a common pathological feature. Pan-vascular diseases have attracted widespread attention due to the high healthcare burden that accompanies high morbidity. Inflammation is the core pathogenesis of pan-vascular diseases. Targeted anti-inflammatory strategies have achieved certain success in basic research. However， due to the increased risk of infection， their clinical application has been hindered. Simiao Yong'an Tang （SMYAT）， which has the effects of nourishing Yin， detoxifying， and activating blood， demonstrates unique therapeutic advantages. Clinical evidence indicates that SMYAT alone or in combination with conventional Western Medicine/other compound formulas/non-drug therapies can effectively alleviate the clinical symptoms and traditional Chinese medicine （TCM） syndromes of pan-vascular diseases. At the same time， it can reduce the serum levels of inflammatory factors and the risk of infection， improve glucose and lipid metabolism and blood viscosity， and promote wound healing， thereby enhancing the quality of life. The research on the pharmacological material basis indicates that when SMYAT enters the bloodstream， it can be converted into various active components such as harpagide， harpagoside， and chlorogenic acid. Basic research suggests that SMYAT can exert anti-inflammatory effects through multiple pathways and targets， such as interfering with immune cell adhesion and aggregation， macrophage polarization， foam cell autophagy， neovascularization in the outer membrane and plaque， lipid metabolism and cholesterol reverse transport. The current research lacks comprehensive discussion on vascular diseases. In-depth studies on the effects and mechanisms of SMYAT can provide new therapeutic approaches for pan-vascular diseases. Moreover， they help to gain an overall understanding of the disease progression， demonstrating the superiority of the TCM concept of treating different diseases with the same method. This paper provides a systematic overview of the TCM and Western Medicine understanding of pan-vascular diseases， the theoretical framework and material basis of SMYAT， and the progress of clinical and basic research on SMYAT treatment of pan-vascular diseases. The ultimate goal is to provide theoretical evidence and guidance for the development and application of SMYAT in the field of pan-vascular diseases. In the future， further research should be conducted to standardize the compound formula and explore the mechanism of treatment with integrated TCM and Western Medicine.

Pan-vascular diseases are a group of diseases involving the systemic vascular system， with vascular lesions （especially atherosclerosis） as a common pathological feature. Pan-vascular diseases have attracted widespread attention due to the high healthcare burden that accompanies high morbidity. Inflammation is the core pathogenesis of pan-vascular diseases. Targeted anti-inflammatory strategies have achieved certain success in basic research. However， due to the increased risk of infection， their clinical application has been hindered. Simiao Yong'an Tang （SMYAT）， which has the effects of nourishing Yin， detoxifying， and activating blood， demonstrates unique therapeutic advantages. Clinical evidence indicates that SMYAT alone or in combination with conventional Western Medicine/other compound formulas/non-drug therapies can effectively alleviate the clinical symptoms and traditional Chinese medicine （TCM） syndromes of pan-vascular diseases. At the same time， it can reduce the serum levels of inflammatory factors and the risk of infection， improve glucose and lipid metabolism and blood viscosity， and promote wound healing， thereby enhancing the quality of life. The research on the pharmacological material basis indicates that when SMYAT enters the bloodstream， it can be converted into various active components such as harpagide， harpagoside， and chlorogenic acid. Basic research suggests that SMYAT can exert anti-inflammatory effects through multiple pathways and targets， such as interfering with immune cell adhesion and aggregation， macrophage polarization， foam cell autophagy， neovascularization in the outer membrane and plaque， lipid metabolism and cholesterol reverse transport. The current research lacks comprehensive discussion on vascular diseases. In-depth studies on the effects and mechanisms of SMYAT can provide new therapeutic approaches for pan-vascular diseases. Moreover， they help to gain an overall understanding of the disease progression， demonstrating the superiority of the TCM concept of treating different diseases with the same method. This paper provides a systematic overview of the TCM and Western Medicine understanding of pan-vascular diseases， the theoretical framework and material basis of SMYAT， and the progress of clinical and basic research on SMYAT treatment of pan-vascular diseases. The ultimate goal is to provide theoretical evidence and guidance for the development and application of SMYAT in the field of pan-vascular diseases. In the future， further research should be conducted to standardize the compound formula and explore the mechanism of treatment with integrated TCM and Western Medicine.

This paper analyzed the traditional Chinese medicine （TCM） and western medical understanding of coronary microvascular disease （CMVD） from the three dimensions of "disease-syndrome-symptom". In western medicine， by summarizing the suspected diagnosis and understanding of CMVD， it is believed that inflammatory responses and vascular endothelial damage are the key mechanisms of the pathogenesis. From the perspective of TCM， the disease location is at blood， vessels and heart， and the fundamental cause is spleen and kidney depletion， closely realted to phlegm， stasis， toxin， wind and qi. Integrating the understanding of both TCM and western medicine， clinical treatment advocates taking the CMVD pathology as the base， and the TCM understanding of pathogenesis as the main focus. The properties of Chinese herbal medicinals is used as the guidance for medication， and the pharmacological understanding as the assisstance of treatment， with the medical history and the severity of the condition are additionally considered. It is finally proposed that during the acute phase， the methods of nourishing yin and resolving toxins， softening hardness and dissipating masses， dispelling wind and unblocking collaterals should be applied to alleviate the emergency. In the subacute phase， the focus should be on raising and lifting qi promote its movement， with flexible use of medicinals that can unblock yang. In the remission phase， the method of tonifying spleen and fortifying kidney should be used to maintain the stability of the condition.