1.Validation of the OMRON automated oscillometric blood pressure monitoring device HEM 7156 using the association for the advancement of medical instrumentation/european society of hypertension/international organization for standardization (AAMI/ESH/ISO) universal standard (ISO 81060-2:2018).
Benjamin A. BALMORES JR. ; Raymond V. OLIVA ; Deborah Ignacia DAVID-ONA ; Dolores D. BONZON ; Alejandro Bimbo F. DIAZ ; Arnold Benjamin C. MINA ; Marlon T. CO ; Erick S. MENDOZA ; Alberto A. ATILANO ; Leilani B. MERCADO-ASIS ; Adriel E. GUERRERO ; Lourdes Ella G. SANTOS
Philippine Journal of Cardiology 2025;53(2):52-57
BACKGROUND
Blood pressure (BP) is a vital sign that is essential in the management of hypertension, thus, there is a need for accurate measurement of BP. This will allow for proper diagnosis and management of hypertension preventing cardiovascular morbidity and mortality among Filipino patients.
METHODOLOGYThis validation study utilized the US Association for the Advancement of Medical Instrumentation/European Society of Hypertension/International Organization for Standardization (AAMI/ESH/ISO) protocol for BP monitors. A total of eighty-five (85) participants had their BP measured using both the HEM 7156 and a validated aneroid sphygmomanometer. The same-sequential BP measurement was recommended to be used and a total of nine readings were collected per individual. The mean average of BP and standard deviation were extracted from the measurements. The AAMI/ESH/ISO recommends the use of certain criteria for individual BP readings (criterion 1) and individual participants (criterion 2). Appropriate statistical analysis was used for other demographic data.
RESULTSThe participants had an average age of 34 years, more than half were females, and not diagnosed with hypertension. Individuals who were diagnosed with hypertension had no other comorbidities and were on single pill only. The average arm circumference was 26.9 cm. Blood Pressure (BP) readings were adequate based on the protocol. Validity results showed that for criterion 1, systolic blood pressure (SBP) difference was 3.4 ± 7.4 mmHg, while diastolic blood pressure (DBP) was 2.0 ± 8.0 mmHg. The results for criterion 2 showed for SBP was 3.3 ± 5.3 mmHg, while DBP was 1.9 ± 6.6 mmHg. The results satisfied a passing grade on the validation protocol set by the AAMI/ESH/ISO.
CONCLUSIONThis study showed that OMRON HEM 7156 is validated as a BP apparatus and may be recommended for Philippine use.
Human ; Hypertension
2.Hypertension in women: From reproductive to postmenopausal phase.
Philippine Journal of Cardiology 2025;53(2):107-120
Globally, an estimated 1.28 billion adults aged 30–79 years have hypertension (HTN), most of them (two-thirds) living in low- and middle-income countries (WHO 2023 report). The demographic of blood pressure (BP) in both genders differs with aging. In peopleyounger than 65 years of age, BP levels in men are higher compared to those of women. Conversely, at age 65 years and older, more women have been found to have elevated BP. Likewise, the cumulative incidence of increased adverse cardiovascular (CV) events in women has been reported as they age. Aside from aging, the influence of bio-social factors among women has been implicated in the development of HTN, such as health status—use of oral contraceptive pills (OCP), menopausal stage, obesity and having polycystic ovarian syndrome (PCOS) disease and socioeconomic condition—educational background, employment status and nuclear family setting. This paper will discuss how these factors affect the development of HTN and the approach of management among affected women from the reproductive to postmenopausal stage of life.
Human ; Female ; Hypertension
3.Systemic Hormonal Unloading (SHU) in secondary hypertension: Addressing the long-term adverse cardiovascular outcomes
Leilani B. B. Mercado-Asis ; Felisse Carmen Gomez-Tuazon ; Florence Rochelle Gan ; Chandy Lou Malong-Calanoc
Journal of Medicine University of Santo Tomas 2024;8(1):1390-1397
Excess hormone production from adrenal tumors caused by primary hyperaldosteronism or pheochromocytoma are common etiologies for secondary hypertension. Studies have shown that sustained long-term circulating hormones in excess affect the blood vessels and cardiac structures. Inflammation of cardiomyocytes leads to fibrosis and eventual cardiomyopathy and is clinically presented as arrhythmia, nonfatal myocardial infarction, heart failure, or even death. The tissue changes and/or impaired cardiac function are reversible if early diagnosis and removal of the adrenal tumor by unilateral adrenalectomy is done. However, the condition becomes challenging if the adrenal lesions are bilateral. This article introduces the concept of systemic hormonal unloading and will discuss the philosophy of quality of life in managing bilateral adrenal disease.
Hyperaldosteronism
;
Pheochromocytoma
;
Quality of Life
4.Educating and promoting health - A community-based prevention and control program for soil-transmitted helminth infections in a community in Rodriguez, Rizal
Diana Leah Mendoza ; Leilani B. Mercado-Asis
Journal of Medicine University of Santo Tomas 2023;7(1):1161-1168
The impact of soil-transmitted helminthiases on the overall health of an individual may lead to significant morbidity related to the number of worms harbored by the person. Light intensity infections usually present no significant effect on the individual except in times of more massive infections, in which complications may lead to impaired growth and physical development. With this, international and local health programs aim to increase the proportion of community households aware of proper helminthiases prevention and control strategies. Access to potable water, and drainage and disposal or reuse of household water, to safe and sanitary facilities, safe human excreta disposal, and proper management of solid waste appropriate information on prevention and treatment of soil-transmitted helminthiases (STH), and dissemination of key messages to promote safe water storage, hand washing, bathing practices, safe food handling, latrine use and wearing of shoes and regular deworming practices are recommended points of intervention to reduce the prevalence of helminthiases in children and other high-risk population groups. Guided with the principles of health promotion and education and the health program framework of the Department of Health (DOH) and World Health Organization (WHO), community health may be achieved equitably by leveraging accurate information, community mobilization, and sustainable health partnerships.
Health Promotion
;
Health Education
;
Communicable Diseases
;
Public Health
5.Evidence-Based Teaching (EBT) in medical education: Addressing the challenges of bridging didactic knowledge to clinical application
Leilani B. Mercado-Asis ; Melvin R. Marcial
Journal of Medicine University of Santo Tomas 2023;7(1):1205-1214
Although evidence-based teaching has been adopted in various learning disciplines, its adoption in medical education remains challenging. To graduate a full-fledged well-rounded physician equipped to face the real-world challenges of diagnosis and treating diseases is the ultimate goal of every medical institution. Medical students’ clinical competence is anchored on the approach of facilitators’ acquired teaching expertise and how they apply learned techniques to connect basic knowledge to clinical skill enhancement. Are these approaches within the realm of evidence-based teaching? The subsequent discussion will elaborate on proven effective strategies [Problem-Based Learning (PBL), Outcome-Based Education (OBE)] and how a strategic teaching and learning tool [Target-Oriented Clinical Skill Enhancement (TOCSE)] has proven to address the issue.
Education, Medical
;
6.Geriatric medicine in the medical curriculum: A MUST in the globally aging world
Leilani B Mercado-Asis ; Ma. Lourdes Domingo-Maglinao
Journal of Medicine University of Santo Tomas 2022;6(2):944-951
Geriatrics is a branch of medicine concerned with diagnosing, treating, and preventing diseases in
older people and problems specific to aging. The World Health Organization (WHO) has reported that the number of people aged 65 or older is projected to grow from an estimated 524 million in 2010 to nearly 1.5 billion in 2050. The burden of diseases in the aging population will dramatically impact healthcare expenses in low- and middle-income countries and even developed ones. A preventive approach is essential. The role of medical institutions and inclusion of geriatrics in the medical curriculum have become important. However, incorporating geriatrics into the medical curriculum is associated with various issues and challenges: compact preexisting curriculum, attitudes of teachers and students, and shortage of teaching geriatricians. An individualized institutional approach to curricular integration guided by the American Geriatrics Society’s minimum required competencies for the undergraduate will circumvent these challenges.
CURRICULUM
;
EDUCATION
7.Giving insulin is not a guessing game: Insulin replacement therapy in type 2 diabetes mellitus.
Nenuel Angelo B. LUNA ; Leilani B. MERCADO-ASIS
Journal of Medicine University of Santo Tomas 2022;6(1):868-880
In 2021, 537 million adults were living with diabetes. Being a progressive disease, there would eventually be failure of oral hypoglycemic agents (OHA) to maintain good glycemic control and a majority will require insulin. However, optimal glycemic control has not been satisfactory in a significant proportion of patients who were on insulin therapy. Patient factors (eg, awareness, compliance, socioeconomic) have been identified but physician-related factors are as important. These include incorrect choice and inappropriate combination of insulin therapy which could be corrected by making the treatment physiologic. The purpose of this article is to improve management decisions in type 2 diabetes by reviewing its pathophysiology and identifying the optimum insulin regimen that could mimic such. Since eventual beta cell failure is central to its pathophysiology, it is but reasonable to replace insulin by mimicking its physiologic secretion. Hence, the term Insulin Replacement Therapy (IRT) should be utilized. This could be provided by the combination of premix insulin (ie, NPH + regular insulin) and rapid-acting insulin which has been reported to provide an initial 17.5% HbA1c reduction and even 18% reduction on 5-year follow-up providing sustainable control. A stepwise approach is an effective tool for insulin intensification. Hypoglycemia in insulin therapy could be prevented with an appropriate dietary regimen through automatic snacking.
Diabetes Mellitus, Type 2
8.Safe, Nourishing, Accessible Community Kitchen (S.N.A.C.K.): A community kitchen manual for public health emergencies.
Kathleen N. CRUZADA ; Leilani B. MERCADO-ASIS ; Julie T. LI-YU ; Roland PANALIGAN
Journal of Medicine University of Santo Tomas 2022;6(1):898-905
Objective: The project aims to develop a community kitchen manual for public health emergencies.
Participants: The officers and members of the Samahan ng Nagkakaisang Kababaihan ng BASECO served as community respondents for this project. These eight women were in charge of the community kitchen operations, particularly the feeding program during the COVID-19 pandemic.
Implementation: The whole project comes in three phases. The design stage was executed in phase one of this project. The phase one also focused on the development of manual content based on available literatures and considered the interviews conducted with respondents.
Discussion: The manual contains guidelines on food safety and meal preparations. Based on the interview, the proponents identified specific contents that must be included in the guidelines, as compared with the need to improve current operations of the group's community kitchen. Looking at the activities of the community, the proponents indicated the food flow guidelines to ensure a safe, nourishing and accessible community kitchen (S.N.A.C.K).
Conclusion: The designed community kitchen manual may be of use to lay groups putting up community kitchens, since there is no existing manual in the Philippines. However, phases two and three must be conducted to validate its usefulness and accuracy in the field.
Food Security ; Food Safety
9.Improving systems to promote research integrity.
Leilani B. MERCADO-ASIS ; Ma. Lourdes P. DOMINGO-MAGLINAO
Journal of Medicine University of Santo Tomas 2022;6(S1):32-38
Research integrity is manifested thru the use of honest and verifiable research methods with adherence to accepted professional codes. Recently, trustworthiness in research has been challenged by various forms of research misconduct, such as analytical flexibility, data dredging, HARKing (hypothesis after research knowledge), plagiarism, and selective and distorted reporting. Drivers of research misconduct have been identified as institutional--publication incentives to pursue a career, researcher--metric of success is publication volume, and the journal-- more likely to accept papers with positive. The open-access mode propelling the proliferation of predatory journals is causing a dilemma to sound research reporting. Measures were established to curtail research integrity challenges, such as study registration, open data, common reporting standards, a team of rivals, and blind analysis. This report will elaborate and provide insight into what influenced research misconduct, how it can be mitigated, and how to maintain a credible research environment.
Scientific Misconduct
;
Predatory Journals As Topic
10.Target-Oriented Clinical Skill Enhancement (TOCSE) builds up confidence of fourth-year medical students during first-time patient encounter: An effective bridging tool after online didactic undergraduate classes during the COVID-19 pandemic
Maria Faye Anne S GOMEZ ; Leonid D ZAMORA ; Paul John ABLAZA ; Melvin Remulla MARCIAL ; Leilani B MERCADO-ASIS
Journal of Medicine University of Santo Tomas 2022;6(S1):114-125
Clinical Competence


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