Objective:The SF-36 Scale was utilized to compare the differences in the dimensions of survival quality between subway microwave contact personnel and administrative personnel to provide a scientific basis for improving the quality of life of microwave contact personnel.Methods:In October 2023, 264 occupational personnel exposed to microwaves were selected as the microwave exposure group, and 104 administrative personnel not exposed to microwaves in a railroad enterprise were selected as the administrative control group. The self-administered basic data questionnaire and SF-36 Scale were applied to investigate the basic conditions, daily behaviors and survival quality of the research objects. And the microwave exposure doses of each post were measured. The differences in basic conditions, daily behaviors and survival quality of the microwave exposure group and the administrative control group were analyzed. And logistic regression was used to analyze the influencing factors of survival quality in the microwave exposure group.Results:There were significant differences in gender, age, marital status, smoking status and sleep status between the microwave exposure group and the administrative control group ( P<0.05) . The microwave exposure group had lower scores than the administrative control group in the six dimensions of role physical, body pain, general health, vitality, social function, mental health and SF-36 average total score, and had higher score in reported health transition ( P<0.05) . The logistic regression analysis showed that the probability of low total SF-36 score in microwave exposure group with bachelor's degree or above was 0.46 times that of junior college degree (95% CI: 0.24-0.90, P=0.023) . The probability of low total SF-36 score in microwave exposure group with exercised 4 or more times per week was 4.27 times that of those who never or occasionally exercised (95% CI: 1.41-13.00, P=0.010) . The probabilities of low total SF-36 score in microwave exposure group with sleep light and dream, wake up in the middle night and hard to fall asleep were 11.04 and 7.38 times higher than those without sleep disturbance (95% CI: 3.35-36.32, P<0.001; 95% CI: 1.42-38.50, P=0.018) . The probability of low total SF-36 score in microwave exposure group with daily dose of 1.74 μW·h/cm 2 was 1.75 times that of the daily dose of 1.02 μW·h/cm 2 (95% CI: 1.08-3.82, P=0.008) . Conclusion:The education level, physical exercise, sleep status and microwave exposure dose are important factors affecting the survival quality of microwave exposed personnel. Occupational health education and behavioral life intervention should be strengthened to improve their survival quality.

Objective:The SF-36 Scale was utilized to compare the differences in the dimensions of survival quality between subway microwave contact personnel and administrative personnel to provide a scientific basis for improving the quality of life of microwave contact personnel.Methods:In October 2023, 264 occupational personnel exposed to microwaves were selected as the microwave exposure group, and 104 administrative personnel not exposed to microwaves in a railroad enterprise were selected as the administrative control group. The self-administered basic data questionnaire and SF-36 Scale were applied to investigate the basic conditions, daily behaviors and survival quality of the research objects. And the microwave exposure doses of each post were measured. The differences in basic conditions, daily behaviors and survival quality of the microwave exposure group and the administrative control group were analyzed. And logistic regression was used to analyze the influencing factors of survival quality in the microwave exposure group.Results:There were significant differences in gender, age, marital status, smoking status and sleep status between the microwave exposure group and the administrative control group ( P<0.05) . The microwave exposure group had lower scores than the administrative control group in the six dimensions of role physical, body pain, general health, vitality, social function, mental health and SF-36 average total score, and had higher score in reported health transition ( P<0.05) . The logistic regression analysis showed that the probability of low total SF-36 score in microwave exposure group with bachelor's degree or above was 0.46 times that of junior college degree (95% CI: 0.24-0.90, P=0.023) . The probability of low total SF-36 score in microwave exposure group with exercised 4 or more times per week was 4.27 times that of those who never or occasionally exercised (95% CI: 1.41-13.00, P=0.010) . The probabilities of low total SF-36 score in microwave exposure group with sleep light and dream, wake up in the middle night and hard to fall asleep were 11.04 and 7.38 times higher than those without sleep disturbance (95% CI: 3.35-36.32, P<0.001; 95% CI: 1.42-38.50, P=0.018) . The probability of low total SF-36 score in microwave exposure group with daily dose of 1.74 μW·h/cm 2 was 1.75 times that of the daily dose of 1.02 μW·h/cm 2 (95% CI: 1.08-3.82, P=0.008) . Conclusion:The education level, physical exercise, sleep status and microwave exposure dose are important factors affecting the survival quality of microwave exposed personnel. Occupational health education and behavioral life intervention should be strengthened to improve their survival quality.

Objective To investigate the relationship between forkhead/winged helix transcription factor (Foxp) 3 gene polymorphisms and susceptibility and phenotype of Crohn's disease (CD) in Han nationality in Zhejiang province.Methods From January 2007 to December 2015,268 diagnosed CD patients and 490 healthy controls were enrolled.The four single nucleotide polymorphism (SNP) of Foxp3 rs3761547,rs2232365,rs2294021 and rs3761548 were examined by a SNaPshot technique,and their relation with the efficacy of infliximab was evaluated.The linkage disequilibrium (LD) and haplotype were also analyzed.Unconditional Logistic regression analysis was performed for statistical analysis.Results There was no significant difference in the four mutant alleles and genotype frequencies between 31 patients with effective infliximab treatment and 19 patients with ineffective treatment (all P＞0.05).The results of LD analysis indicated that the above four SNP were in a tight linkage.The frequency of haplotype GCGC of male CD group was 29.20％ (40/137),which was higher than that of male healthy control group (19.37％,43/222),and the difference was statistically significant (odd ratio (OR)=1.717,95％ confidence interval (CI) 1.045 to 2.820,P=0.032).The frequency of haplotype ACGA of female CD group was 13.36％ (35/262),which was lower than that of female healthy control group (19.03％,102/536),and the difference was statistically significant (OR=0.656,95％CI 0.433 to 0.995,P=0.046).The frequency of haplotype ATAC of male colon (L2) type was 25.93％ (7/27),which was lower than that of ileocecal colon (L3) type (75.38％,49/65),and the difference was statistically significant (OR=0.114,95％CI 0.041 to 0.320,P＜0.01).The frequency of haplotype GCGC of male L2 type was 51.85％ (14/27),which was higher than that of L3 type (9.23％,6/65),and the difference was statistically significant (OR=10.590,95％CI 3.423 to 32.758,P＜0.01).The frequency of haplotype ATAC of male stenotic (B2) type was 73.21％ (41/56),which was higher than that of nonstenotic and nonpenetrated (B1) type (47.30％,35/74),and the difference was statistically significant (OR=0.328,95％CI 0.156 to 0.693,P=0.003).The frequency of haplotype GCGC of male B2 type was 17.86％ (10/56) which was lower than that of nonstenotic and nonpenetrated (B1) type (39.19％,29/74),and the difference was statistically significant (OR=2.946,95％CI 1.295 to 6.784,P=0.009).The frequency of haplotype ACGA of male penetrated (B3) type was 71.43％ (5/7),which was higher than that of nonstenotic and nonpenetrated (B1) type (12.16％,9/74),and the difference was statistically significant (OR =0.055,95％ CI 0.009 to 0.329,P ＜ 0.01).Conclusion Foxp3 (rs3761547,rs2232365,rs2294021,rs3761548) gene polymorphisms are associated with the susceptibility and phenotype of CD in Chinese Han patients,but not related with the efficacy of infliximab.