Objective To investigate the impact of gaseous pollutants (SO2,NO2,CO,O3) on hospital admissions,hospitalization costs,and length of stay for cardiovascular diseases in seven cities of Guangdong Province. Methods A total of 2,010,905 patients with cardiovascular diseases from seven cities in Guangdong Province between January 2017 and December 2019 were included. Demographic characteristics and hospitalization data for cardiovascular disease inpatients were obtained from the Guangdong Province Electronic Healthcare Information System. Daily exposure concentrations of SO2,NO2,CO and O3 were extracted from the China High-Air-Pollution Dataset. The impact of air pollutants on cardiovascular diseases in the seven cities of Guangdong Province was estimated using a multi-step time-series analysis. Results SO2,NO2,and CO concentrations on the day of admission (lag0) were positively associated with the risk of cardiovascular admissions,hospitalization costs,and length of stay,with NO2 exhibiting the strongest effect. Additionally,there was a lagged negative impact of NO2 and CO,while O3 concentrations were inversely correlated with the number of cardiovascular admissions,hospitalization costs,and length of stay over the lag0-7 period. Conclusions Short-term exposures to SO2,NO2,and CO are likely positively associated with the disease burden in CVD patients. Furthermore,given the more substantial adverse effects of NO2,enhanced monitoring of NO2 remains essential. However,as this study is retrospective,additional research is warranted.

Objective To assess the relationship between environmental pollution and mortality,along with the mediating function of socioeconomic status(SES).Methods Data sourced from the UK Biobank were utilized,encompassing 318,974 participants.SES was evaluated through the Townsend Deprivation Index(TDI).Cox regression models were employed to explore the associations between environmental pollution and all-cause mortality,as well as cause-specific mortality.Linear regression analysis was conducted to analyze the mediating role of TDI levels in the relationship between pollution and mortality risk.Results During the follow-up period,24 909 deaths were recorded,with the participants having an average age of 61.5 years.Except for PM10,all pollutants were found to be associated with all-cause mortality,and PM2.5 was linked to cause-specific mortality.Higher pollution scores were correlated with elevated all-cause mortality hazard ratios(HRs),reaching 1.13(95%CI:1.09～1.18)in the highest quintile.Greater socioeconomic deprivation was also associated with higher all-cause mortality HRs,specifically 1.36(95%CI:1.24～1.49)for the most deprived group.Conclusions Environmental pollution constitutes a risk factor for mortality,with SES playing a mediating role.Besides public health interventions and personal behavioral guidance,innovative social policies and financial support mechanisms are requisite to improve the overall environment in impoverished regions.

Objective To investigate the impact of gaseous pollutants (SO2,NO2,CO,O3) on hospital admissions,hospitalization costs,and length of stay for cardiovascular diseases in seven cities of Guangdong Province. Methods A total of 2,010,905 patients with cardiovascular diseases from seven cities in Guangdong Province between January 2017 and December 2019 were included. Demographic characteristics and hospitalization data for cardiovascular disease inpatients were obtained from the Guangdong Province Electronic Healthcare Information System. Daily exposure concentrations of SO2,NO2,CO and O3 were extracted from the China High-Air-Pollution Dataset. The impact of air pollutants on cardiovascular diseases in the seven cities of Guangdong Province was estimated using a multi-step time-series analysis. Results SO2,NO2,and CO concentrations on the day of admission (lag0) were positively associated with the risk of cardiovascular admissions,hospitalization costs,and length of stay,with NO2 exhibiting the strongest effect. Additionally,there was a lagged negative impact of NO2 and CO,while O3 concentrations were inversely correlated with the number of cardiovascular admissions,hospitalization costs,and length of stay over the lag0-7 period. Conclusions Short-term exposures to SO2,NO2,and CO are likely positively associated with the disease burden in CVD patients. Furthermore,given the more substantial adverse effects of NO2,enhanced monitoring of NO2 remains essential. However,as this study is retrospective,additional research is warranted.

Objective To assess the relationship between environmental pollution and mortality,along with the mediating function of socioeconomic status(SES).Methods Data sourced from the UK Biobank were utilized,encompassing 318,974 participants.SES was evaluated through the Townsend Deprivation Index(TDI).Cox regression models were employed to explore the associations between environmental pollution and all-cause mortality,as well as cause-specific mortality.Linear regression analysis was conducted to analyze the mediating role of TDI levels in the relationship between pollution and mortality risk.Results During the follow-up period,24 909 deaths were recorded,with the participants having an average age of 61.5 years.Except for PM10,all pollutants were found to be associated with all-cause mortality,and PM2.5 was linked to cause-specific mortality.Higher pollution scores were correlated with elevated all-cause mortality hazard ratios(HRs),reaching 1.13(95%CI:1.09～1.18)in the highest quintile.Greater socioeconomic deprivation was also associated with higher all-cause mortality HRs,specifically 1.36(95%CI:1.24～1.49)for the most deprived group.Conclusions Environmental pollution constitutes a risk factor for mortality,with SES playing a mediating role.Besides public health interventions and personal behavioral guidance,innovative social policies and financial support mechanisms are requisite to improve the overall environment in impoverished regions.

Infantile colic is a common self-limiting condition that causes significant distress to parents and caregivers. There is no clear cause, gold standard remedy or preventative action. The role of the family physician is to rule out sinister causes while providing counselling and reassurance for parents. The mainstay of management is parental support and reassurance while looking out for red flags in the baby such as fever, lethargy, distended abdomen and failure to thrive. This article provides a framework to approaching infantile colic and practical pointers to share with parents.
Caregivers ; Colic ; diagnosis ; therapy ; Crying ; Evidence-Based Medicine ; Humans ; Infant ; Infant Formula ; Infant, Newborn ; Muscle Hypertonia ; diagnosis ; Parenting ; Parents ; Pediatrics ; methods ; Physicians, Family ; Primary Health Care ; methods ; Professional-Patient Relations