No abstract available.
Exercise* ; Humans

Ethanolamine ; Head ; Hemangioma ; Laser Therapy ; Neck ; Oleic Acid ; Oleic Acids ; Sclerotherapy ; Vascular Malformations

BACKGROUND: To evaluate the clinical characteristics of lung cancer patients in Korea, where there is a higher number of smokers than in Western countries. METHODS: A retrospective study was performed on 1655 lung cancer patients, who were diagnosed at a university hospital between September 1996 and August 2005. Age, gender, cell types and clinical stage were analysed. Of 941 patients, who responded to a questionnaire at the time of diagnosis, the smoking habits, occupational history, family history of lung cancer in the first-degree relatives, coexisting diseases (diabetes mellitus and cardiovascular disease), body weight loss, ECOG performance status and presenting symptoms, were examined prospectively. In addition, coexisting diseases including chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis and active pulmonary tuberculosis were evaluated. RESULTS: Of the 1655 patients, the male to females ratio was 3.6. Squamous cell carcinoma was the most common cancer whereas adenocarcinoma was more common in lifetime nonsmokers or women. 19.9% of the patients were non smokers and 80.1% ever smokers. Since 2000, there was an increase in the incidence of adenocarcinoma with a corresponding decrease in the incidence of squamous cell carcinoma. 6.2% of patients were asymptomatic. A coincident diagnosis of chronic obstructive pulmonary disease, cardiovascular disease, diabetes mellitus, active pulmonary tuberculosis, and idiopathic pulmonary fibrosis was made in: 44.1%, 22.2%, 10.7%, 3.9%, and 1.6% of patients, respectively. A positive family history of lung cancer in the first-degree relatives was identified in 4.4% of patients. An occupational history relevant to lung cancer was identified in 12.2% of patients. CONCLUSION: There is a high proportion of cigarette smokers in Korean lung cancer patients. The most common cell type was squamous cell carcinoma. However, a more detailed, prospective study of the clinical characteristics will be needed to better characterize lung cancer in Korea.
Adenocarcinoma ; Body Weight ; Carcinoma, Squamous Cell ; Cardiovascular Diseases ; Diabetes Mellitus ; Diagnosis ; Female ; Humans ; Idiopathic Pulmonary Fibrosis ; Incidence ; Korea ; Lung Neoplasms* ; Lung* ; Male ; Prospective Studies ; Pulmonary Disease, Chronic Obstructive ; Surveys and Questionnaires ; Retrospective Studies ; Smoke ; Smoking ; Tertiary Care Centers* ; Tobacco Products ; Tuberculosis, Pulmonary

OBJECTIVE: To discover the etiology of birth defects and low birth weight, it is necessary to establish epidemiological birth defects monitoring system in Korea. Our aim was to develop new practical model in Incheon to establish birth defects monitoring system to evaluate the incidence rate and patterns of birth defects in Korea. METHODS: Public health center and private hospitals and clinics participated in this monitoring system. Web based reporting system have been built. Trained nurses actively collected the records obtained from delivery units in the participating hospitals during 2 years (first year: December 1st, 1998-November. 31, 1999; second year: January 1 st, 2000-December 31 th, 2000). RESULTS: Through this monitoring system at 1 st year and 2 nd year, we observed 25 birth defect cases from 2482 births, 28 birth defect cases from 3490 births including live births and stillbirths. The incidence of birth defect per thousand person was 10.1, 8.0 respectively. At 1st year, the highest proportion of birth defects was 28.0% in musculoskeletal system. The proportion of birth defects in gastrointestinal system, cardiovascular system and cleft lip & cleft palate were 20.0%, 12.0%. 12.0%. At 2 nd year, the highest proportion of birth defects was 21.4% in gastrointestinal system The proportion of birth defects in cardiovascular system and musculoskeletal system were 17.9% and 14.3%. CONCLUION: In conclusion, we could build population-based monitoring system for birth defects successfully in Yonsu gu, Incheon. To establish population-based monitoring system for birth defects in Korea, it is necessary to organize the reporters of public health center and private hospitals and clinics, to build an available reporting system, and to extend participating centers for birth defects monitoring systems.
Cardiovascular System ; Cleft Lip ; Cleft Palate ; Congenital Abnormalities* ; Environmental Exposure ; Hospitals, Private ; Humans ; Incheon* ; Incidence ; Infant, Low Birth Weight ; Infant, Newborn ; Korea ; Live Birth ; Musculoskeletal System ; Parturition* ; Public Health ; Stillbirth

Problems of birth defects and low birth weight are important issues of public health because most infant mortality are caused by these two. To discover the etiology of birth defects and low birth weight, it is necessary to establish epidemiological birth defects monitoring system in Korea. With the rapid growing of internet usage in korea, the computer network has become the popular means of communicating and sharing of information. Our aim was to develop web-based reporting and database management system in Incheon to establish birth defects monitoring system to evaluate the incidence rate and patterns of birth defects in Korea. Public health center and private hospitals and clinics participated in this monitoring system. Web based reporting system have been built and operated during 2 years (first year: December 1st, 1998-November. 31, 1999; second year: January 1st, 2000 - December 31th, 2000). Trained nurses actively collected the records obtained from delivery units in the participating hospitals. During first and second year, the incidence rate of birth defect per thousand person was 10.0 and 8.0 respectively. In conclusion, we could build web-based monitoring system for birth defects successfully in Yonsu gu, Incheon. It could be a model of national standard for population-based monitoring system for birth defects in Korea.
Congenital Abnormalities* ; Database Management Systems ; Hospitals, Private ; Humans ; Incheon* ; Incidence ; Infant ; Infant Mortality ; Infant, Low Birth Weight ; Infant, Newborn ; Internet ; Korea ; Parturition* ; Public Health

Seventy-five patients with moyamoya disease were admitted at Kyung Hee University Hospital from 1978 to 1993. Of these, we followed up fourty-five cases who had been treated conservatively for the study of the natural history of moyamoya disease. Seven operated cases and six dead patients during admission were excluded in this study and sixteen cases were lost to follow-up. There were 16 males and 29 females. The hemorrhagic group was twenty-three cases and the non-hemorrhagic group was twenty-two cases. On angiographic findings, the typical type was twenty-eight cases and the atypical type was seventeen cases. Twenty-one cases(91%) of the hemorrhagic group were over twenty years old and sixteen cases(73%) of the non-hemorrhagic group were under twenty years old. The mean follow-up period was 66 months(range 6 months to 15 year 4 months). Nineteen cases had reattack, but most of them had good result except only two cases who died due to huge intracerebral hematoma. Of the sixteen cases, who were under twenty years old and manifested as transient ischemic attack, fifteen cases were improved only with conservative management. The good result of fourty-one cases out of fourty-five with conservative management. suggests that spontaneous collateral circulation had developed well to restore the function of ischemic brain in the natural course of moyamoya disease. Moyamoya disease seems to be not so worse in natural course than expected and further study about natural history will be necessary.
Brain ; Collateral Circulation ; Female ; Follow-Up Studies ; Hematoma ; Humans ; Ischemic Attack, Transient ; Lost to Follow-Up ; Male ; Moyamoya Disease* ; Natural History*

The authors report 4 cases of epidermoid tumor in the cerebello-pontine angle that caused trigeminal neuralgia. Trigeminal neuralgia is mainly caused by vascular compression at the trigeminal root entry zone. In some patients however, the trigeminal nerve can be affected by multiple sclerosis and compressed by a mass within the cerebello-pontine angle(e.g., meningioma, acoustic neurinoma, epidermoid cyst), giant aneurysm, and arteriovenous malformation(AVM). Such benign cerebello-pontine angle tumors may be found in as many as 5 to 8 percent of patients who present with tic nervous system and the initial symptoms caused by this tumor is manifested as facial pain without any other neurological symptoms.
Aneurysm ; Facial Pain ; Humans ; Meningioma ; Microvascular Decompression Surgery ; Multiple Sclerosis ; Nervous System ; Neuroma, Acoustic ; Tics ; Trigeminal Nerve ; Trigeminal Neuralgia*

The choroids plexus papillomas are rare neoplasms of central nervous system, constituting about 0.5% of intracranial tumors. They are most common in children, especially in the first two year of life. In adult, they usually occur within posterior fossa, but cerebellopontine(CP) angle choroids plexus tumor is extremely rare. The authors report two cases of 4th ventricle and CP angle choroids plexus papilloma in adult.
Adult* ; Central Nervous System ; Cerebellopontine Angle* ; Child ; Choroid Plexus* ; Choroid* ; Humans ; Papilloma ; Papilloma, Choroid Plexus*

High doses of corticosteroids have been found to have beneficial effects in various shock states. It has been well recognized that ischemia is one of the important factors in shock states. This prompted us to investigate the effect of high dose methylprednisolone on tourniquet induced ischemia. The results were as follows: 1) The heart rate did not change significantly after tourniquet release in both group. 2) The mean arterial pressure decreased ignificantly at 1 minute after tourniquet release in both group. 3) The PaO2,PaCO2 and HCO-(3) did not change significantly after tourniquet release in both group. 4) The pH decreased significantly at l minute and 5 minutes after tourniquet release in control group and did not change in methylprednisolone group. 5) Base excess increased significantly at 1 minute and 5 munutes after tourniquet release in control group and did not change significantly in methylprednisolone group. In conclusion, the results of this study indicate that methylprednisolone provides a beneficial effect during tourniquet ischemia.
Adrenal Cortex Hormones ; Arterial Pressure ; Heart Rate ; Hydrogen-Ion Concentration ; Ischemia* ; Methylprednisolone* ; Shock ; Tourniquets*

With 4 channel Nicolet-CA 1000 clinical averager and 133 Xenon inhalation method, somatosensory evoked potentials (SSEP), brainstem auditory evoked potentials (BAEP) and regional cerebral blood flow (r-CBF) were studied in 30 patients with ruptured cerebral aneurysms. 8 out of 30 patients had abnormal SSEP, 11 out of 30 patients had abnormal BAEP and 4 out of 14 patients had decreased r-CBF. The SSEP was abnormal in 6 out of 10 patients with severe vasospasm but in only 2 out of 20 patients without vasospasm or with mild and moderate spasm. The BAEP was abnormal in 5 out of 10 patients with severe vasospasm but 6 out of 20 patients without spasm or with mild and moderate spasm. Regional CBF was decreased in 3 out of 4 patients with severe vasospasm but only 1 out of 10 patients without spasm or with mild and moderate spasm. Abnormal SSEP, BAEP & decreased r-CBF in patients with severe vasospasm indicated a poor prognosis. We got the results as follows ; 1) Abnormal SSEP, BAEP and decreased r-CBF are correlated with severity of vasospasm in SAH patients. 2) Abnormal SSEP and BAEP correlated with the clinical status. 3) Brain stem transmission time (BTT) is less sensitive than central conduction time (CCT) as indicator of vasospasm.
Brain Stem ; Evoked Potentials* ; Evoked Potentials, Auditory, Brain Stem ; Evoked Potentials, Somatosensory ; Humans ; Inhalation ; Intracranial Aneurysm ; Prognosis ; Spasm ; Xenon