1.The impact of the laboratory quality management program on colorectal cancer screening using immunochemical fecal occult blood tests in Korea
Hye Ryun LEE ; Sollip KIM ; Hyeongsu KIM ; Yeo-Min YUN ; Ho Jin JEONG ; Minje HAN ; Myeong Hee KIM ; Tae-Hyun UM ; You Kyoung LEE ; Byung Ryul JEON ; Kunsei LEE ; Sail CHUN
Journal of the Korean Medical Association 2025;68(5):338-347
Purpose:
Immunochemical fecal occult blood tests (iFOBT) have been utilized as the primary method for colorectal cancer screening within Korea's National Cancer Screening Program. This study aimed to evaluate the impact of the accreditation program for clinical laboratories and external quality assessment (EQA) programs on colorectal cancer screening.
Methods:
We analyzed the false-positive rates of iFOBT in colorectal cancer screening from 2016 to 2020 according to participation and performance in the Outstanding Laboratory Accreditation Program (OLAP) conducted by the Laboratory Medicine Foundation, and the External Quality Assessment programs run by the Korean Association of External Quality Assessment Service.
Results:
False-positive rates of iFOBT were lower among institutions accredited by OLAP (2.35%) compared with non-accredited (3.04%) and non-participating institutions (5.60%). Similarly, institutions participating in the EQA program exhibited lower false-positive rates (3.79%) compared to non-participants (7.04%). Within the iFOBT-specific EQA program, institutions that passed demonstrated the lowest false-positive rate (3.37%), while failing institutions showed the highest rate (9.07%), surpassing even non-participating institutions (6.44%).
Conclusion
Participation in quality management programs such as OLAP and EQA was associated with lower false-positive rates in iFOBT for colorectal cancer screening. These findings suggest that quality management initiatives can increase the accuracy of iFOBT, potentially improving the effectiveness of colorectal cancer screening programs, and reducing unnecessary follow-up procedures and associated healthcare costs.
2.The impact of the laboratory quality management program on colorectal cancer screening using immunochemical fecal occult blood tests in Korea
Hye Ryun LEE ; Sollip KIM ; Hyeongsu KIM ; Yeo-Min YUN ; Ho Jin JEONG ; Minje HAN ; Myeong Hee KIM ; Tae-Hyun UM ; You Kyoung LEE ; Byung Ryul JEON ; Kunsei LEE ; Sail CHUN
Journal of the Korean Medical Association 2025;68(5):338-347
Purpose:
Immunochemical fecal occult blood tests (iFOBT) have been utilized as the primary method for colorectal cancer screening within Korea's National Cancer Screening Program. This study aimed to evaluate the impact of the accreditation program for clinical laboratories and external quality assessment (EQA) programs on colorectal cancer screening.
Methods:
We analyzed the false-positive rates of iFOBT in colorectal cancer screening from 2016 to 2020 according to participation and performance in the Outstanding Laboratory Accreditation Program (OLAP) conducted by the Laboratory Medicine Foundation, and the External Quality Assessment programs run by the Korean Association of External Quality Assessment Service.
Results:
False-positive rates of iFOBT were lower among institutions accredited by OLAP (2.35%) compared with non-accredited (3.04%) and non-participating institutions (5.60%). Similarly, institutions participating in the EQA program exhibited lower false-positive rates (3.79%) compared to non-participants (7.04%). Within the iFOBT-specific EQA program, institutions that passed demonstrated the lowest false-positive rate (3.37%), while failing institutions showed the highest rate (9.07%), surpassing even non-participating institutions (6.44%).
Conclusion
Participation in quality management programs such as OLAP and EQA was associated with lower false-positive rates in iFOBT for colorectal cancer screening. These findings suggest that quality management initiatives can increase the accuracy of iFOBT, potentially improving the effectiveness of colorectal cancer screening programs, and reducing unnecessary follow-up procedures and associated healthcare costs.
3.The impact of the laboratory quality management program on colorectal cancer screening using immunochemical fecal occult blood tests in Korea
Hye Ryun LEE ; Sollip KIM ; Hyeongsu KIM ; Yeo-Min YUN ; Ho Jin JEONG ; Minje HAN ; Myeong Hee KIM ; Tae-Hyun UM ; You Kyoung LEE ; Byung Ryul JEON ; Kunsei LEE ; Sail CHUN
Journal of the Korean Medical Association 2025;68(5):338-347
Purpose:
Immunochemical fecal occult blood tests (iFOBT) have been utilized as the primary method for colorectal cancer screening within Korea's National Cancer Screening Program. This study aimed to evaluate the impact of the accreditation program for clinical laboratories and external quality assessment (EQA) programs on colorectal cancer screening.
Methods:
We analyzed the false-positive rates of iFOBT in colorectal cancer screening from 2016 to 2020 according to participation and performance in the Outstanding Laboratory Accreditation Program (OLAP) conducted by the Laboratory Medicine Foundation, and the External Quality Assessment programs run by the Korean Association of External Quality Assessment Service.
Results:
False-positive rates of iFOBT were lower among institutions accredited by OLAP (2.35%) compared with non-accredited (3.04%) and non-participating institutions (5.60%). Similarly, institutions participating in the EQA program exhibited lower false-positive rates (3.79%) compared to non-participants (7.04%). Within the iFOBT-specific EQA program, institutions that passed demonstrated the lowest false-positive rate (3.37%), while failing institutions showed the highest rate (9.07%), surpassing even non-participating institutions (6.44%).
Conclusion
Participation in quality management programs such as OLAP and EQA was associated with lower false-positive rates in iFOBT for colorectal cancer screening. These findings suggest that quality management initiatives can increase the accuracy of iFOBT, potentially improving the effectiveness of colorectal cancer screening programs, and reducing unnecessary follow-up procedures and associated healthcare costs.
4.Risk of cancer, cardiovascular disease, thromboembolism, and mortality in patients with rheumatoid arthritis receiving Janus kinase inhibitors: a real-world retrospective observational study using Korean health insurance data
Hong Ki MIN ; Hyeongsu KIM ; Ho Jin JEONG ; Se Hee KIM ; Hae-Rim KIM ; Sang-Heon LEE ; KunSei LEE ; Soon-Ae SHIN ; Jong Heon PARK
Epidemiology and Health 2023;45(1):e2023045-
OBJECTIVES:
This study investigated whether Janus kinase inhibitors (JAKis) raise the risk of cardiovascular disease (CVD), venous thromboembolism (VTE), and cancer in patients with rheumatoid arthritis (RA).
METHODS:
We conducted a real-world retrospective observational study using data obtained from the Korean National Health Insurance Service database. Two data sets were analyzed: tumor necrosis factor inhibitor (TNFi)/JAKi-naive RA patients (set 1) and all RA patients who used TNFis or JAKis (set 2). The incidence rate ratios (IRRs) and hazard ratios (HRs) for acute myocardial infarction (AMI), stroke, cardiovascular (CV)-related mortality, major adverse cardiovascular events (MACE), VTE, arterial thromboembolism (ATE), cancer, and all-cause mortality were compared between the JAKi and TNFi groups.
RESULTS:
Set 1 included 1,596 RA patients (JAKi group: 645; TNFi group: 951), and set 2 included 11,765 RA patients (JAKi group: 2,498; TNFi group: 9,267). No adverse events (AEs) showed significantly higher IRRs in the JAKi groups than in the TNFi groups of sets 1 and 2. The HRs for MACE in the JAKi groups of sets 1 and 2 were 0.59 (95% confidence [CI], 0.35 to 0.99) and 0.80 (95% CI, 0.67 to 0.97), respectively. The JAKi group of set 2 showed a significantly higher risk of all-cause mortality (HR, 1.71; 95% CI, 1.32 to 2.20), but the other AEs did not demonstrate increased risks in the JAKi groups.
CONCLUSIONS
In this study, JAKis did not increase the risk of AMI, stroke, CV-related mortality, MACE, VTE, ATE, or cancer in Korean RA patients relative to TNFis.
5.Requirements for Cerebrovascular Surgery in Comprehensive Stroke Centers in South Korea
Tackeun KIM ; Chang Wan OH ; Hyeon Seon PARK ; Kunsei LEE ; Won Kyung LEE ; Heeyoung LEE
Journal of Korean Neurosurgical Society 2018;61(4):478-484
OBJECTIVE: Cerebrovascular disease (CVD) was the third most common cause of death in South Korea in 2014. Evidence from abroad suggests that comprehensive stroke centers play an important role in improving the mortality rate of stroke. However, surgical treatment for CVD is currently slightly neglected by national policy, and there is still regional imbalance in this regard. For this reason, we conducted a survey on the necessity of, and the requirements for, establishing regional comprehensive cerebrovascular surgery centers (CCVSCs).METHODS: This investigation was performed using the questionnaire survey method. The questionnaire was consisted with two sections. The first concerned the respondent’s opinion regarding the current status of demand and the regional imbalance of cerebrovascular surgery in South Korea. The second section asked about the requirements for establishing regional CCVSCs. We sent the questionnaire to 100 board members of the Korean Society of Cerebrovascular Surgeons.RESULTS: Most experts agreed that cerebrovascular surgery patients were concentrated in large hospitals in the capital area, and 83.6% of respondents agreed that it was necessary to alleviate the regional imbalance of cerebrovascular surgery. With regards to personnel, over 90% of respondents answered that at least two neuro-vascular surgeons and two neuro-interventionists are necessary to establish a CCVSC. Regarding facilities, almost all respondents stated that each CCVSC would require a neuro-intensive care unit and hybrid operating room. The survey asked the respondents about 13 specific neurovascular surgical procedures and whether they were necessary for a regional CCVSC. In the questions about the necessity of cerebrovascular surgical equipment, all seven pieces of equipment were considered essential by all respondents. A further five pieces of equipment were considered necessary on site: computed tomographic angiography, magnetic resonance angiography, conventional angiography, surgical microscope, and surgical navigation. Our results may provide a basis for future policy regarding treatment of cerebrovascular disease, including surgery.CONCLUSION: Raising the comprehensiveness of treatment at a regional level would lower the national disease burden. Policies should be drafted regarding comprehensive treatment including surgery for cerebrovascular disease, and related support plans should be implemented.
Angiography
;
Cause of Death
;
Cerebrovascular Disorders
;
Health Resources
;
Humans
;
Korea
;
Magnetic Resonance Angiography
;
Mortality
;
Operating Rooms
;
Patient Transfer
;
Stroke
;
Surgeons
;
Surgical Equipment
;
Surveys and Questionnaires
6.Latent Class Analysis of Gambling Activities among Korean Adolescents.
Kyonghwa KANG ; Hyeongsu KIM ; Ae Ran PARK ; Hee Young KIM ; Kunsei LEE
Journal of Korean Academy of Nursing 2018;48(2):232-240
PURPOSE: The aim of this study is to identify the types of gambling among adolescents and provide basic prevention information regarding adolescents' gambling problems. METHODS: Secondary data from representative national survey on 2015 Youth Gambling Problems of Korea Center on Gambling Problems were used. Using latent class analysis (LCA), 13 gambling types such as offline and online games of 14,011 adolescents were classified, and gambling experiences and characteristics were analyzed. RESULTS: The subgroups of adolescent gambling were identified as four latent classes: a rare group (84.5% of the sample), a risk group (1.0%), an offline group (11.9%), and an expanded group (2.6%). The types and characteristics of gambling among the latent classes differed. In the risk group, adolescents participated in online illegal sports betting and internet casino, and gambling time, gambling expenses, and the number of gambling types were higher than other groups. CONCLUSION: Gambling frequently occur among adolescent, and the subtypes of gambling did not reveal homogeneous characteristics. In order to prevent adolescent gambling problems, it is a necessary to develop tailored prevention intervention in the nursing field, which is appropriate to the characteristics of adolescent gambling group and can help with early identification.
Adolescent*
;
Gambling*
;
Humans
;
Internet
;
Korea
;
Nursing
;
Primary Prevention
;
Secondary Prevention
;
Sports
7.Health care perspectives on community care
Journal of the Korean Medical Association 2018;61(10):586-589
The Ministry of Health and Welfare announced a plan for community care in March 2018. Community care is a concept of social services that includes residential, welfare, and health care services, as well as direct care. It is a policy to actively prepare for an aged society. Various services must be developed for comprehensive community care. It is especially necessary to ensure that adequate resources are provided for home care and visiting care. To achieve this goal, the benefit policies of health insurance and long-term care insurance must be changed. Community service providers and infrastructure must be expanded, and a diverse professional workforce should be trained. Doctors need training and experience as team leaders, as they will be able to work with nurses, nutritionists, and social workers. It will be particularly important to operate clinics as group practices rather than as solo practices. Change is also needed in community hospitals, which must receive orientations regarding early patient discharge plans and community-centered collaboration. Hospitals should serve as health care safety nets, including short-term stays and same-day care. Regional governance is important for community care. Doctors must work with a variety of institutions, including community health centers, welfare centers, and elderly facilities. Medical professionals should prepare for and lead future social changes.
Aged
;
Community Health Centers
;
Community Health Services
;
Cooperative Behavior
;
Delivery of Health Care
;
Group Practice
;
Health Services for the Aged
;
Home Care Services
;
Hospitals, Community
;
Humans
;
Insurance, Health
;
Insurance, Long-Term Care
;
Nutritionists
;
Patient Discharge
;
Private Practice
;
Social Change
;
Social Welfare
;
Social Work
;
Social Workers
8.Trends in the of epidemiological perspectives on the causality of occupational diseases
Jun Pyo MYONG ; Hyeongsu KIM ; Kunsei LEE ; Soung Hoon CHANG
Journal of the Korean Medical Association 2018;61(8):466-473
The main role of industrial accident compensation insurance is to protect injured workers and their families by providing various benefits. If a certain disease occurs due to work, the worker must prove the causal relationship between the work and the disease, although it is not easy for injured workers to do so. The epidemiological approach to causality is based on a comparison of the incidence rate in exposed and non-exposed groups. Recently, some arguments have been made regarding the application of epidemiological causality in litigation related to tobacco and some environmental-related diseases. The 3 main points of dispute are as follows: 1) the distinction between specific and non-specific diseases and causal inference, 2) the relative risk and the attributable fraction of the causative factor for the related disease, and 3) the application of population-level epidemiological study results to individual causation. Until now, the main approach to the causality of occupational diseases has been proximate causal relationships because of the practical difficulties in applying epidemiological causality to all events. As coverage under the Industrial Accident Compensation Insurance Act expands, the application of epidemiological causality must be considered, as well as the expansion of applicable occupational diseases. Moreover, doing that could provide enough evidence for managers and workers to take steps to prevent occupational disease. The safety net provided by industrial accident compensation insurance for protecting injured workers needs to be implemented on the basis of scientific evidence.
Accidents, Occupational
;
Compensation and Redress
;
Dissent and Disputes
;
Epidemiologic Studies
;
Epidemiology
;
Humans
;
Incidence
;
Insurance
;
Jurisprudence
;
Occupational Diseases
;
Tobacco
9.Trends in the of epidemiological perspectives on the causality of occupational diseases
Jun Pyo MYONG ; Hyeongsu KIM ; Kunsei LEE ; Soung Hoon CHANG
Journal of the Korean Medical Association 2018;61(8):466-473
The main role of industrial accident compensation insurance is to protect injured workers and their families by providing various benefits. If a certain disease occurs due to work, the worker must prove the causal relationship between the work and the disease, although it is not easy for injured workers to do so. The epidemiological approach to causality is based on a comparison of the incidence rate in exposed and non-exposed groups. Recently, some arguments have been made regarding the application of epidemiological causality in litigation related to tobacco and some environmental-related diseases. The 3 main points of dispute are as follows: 1) the distinction between specific and non-specific diseases and causal inference, 2) the relative risk and the attributable fraction of the causative factor for the related disease, and 3) the application of population-level epidemiological study results to individual causation. Until now, the main approach to the causality of occupational diseases has been proximate causal relationships because of the practical difficulties in applying epidemiological causality to all events. As coverage under the Industrial Accident Compensation Insurance Act expands, the application of epidemiological causality must be considered, as well as the expansion of applicable occupational diseases. Moreover, doing that could provide enough evidence for managers and workers to take steps to prevent occupational disease. The safety net provided by industrial accident compensation insurance for protecting injured workers needs to be implemented on the basis of scientific evidence.
10.Health care perspectives on community care
Journal of the Korean Medical Association 2018;61(10):586-589
The Ministry of Health and Welfare announced a plan for community care in March 2018. Community care is a concept of social services that includes residential, welfare, and health care services, as well as direct care. It is a policy to actively prepare for an aged society. Various services must be developed for comprehensive community care. It is especially necessary to ensure that adequate resources are provided for home care and visiting care. To achieve this goal, the benefit policies of health insurance and long-term care insurance must be changed. Community service providers and infrastructure must be expanded, and a diverse professional workforce should be trained. Doctors need training and experience as team leaders, as they will be able to work with nurses, nutritionists, and social workers. It will be particularly important to operate clinics as group practices rather than as solo practices. Change is also needed in community hospitals, which must receive orientations regarding early patient discharge plans and community-centered collaboration. Hospitals should serve as health care safety nets, including short-term stays and same-day care. Regional governance is important for community care. Doctors must work with a variety of institutions, including community health centers, welfare centers, and elderly facilities. Medical professionals should prepare for and lead future social changes.

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