1.Integrating traditional Chinese medicine into disease management in Singapore.
Hui Ping NG ; Linda Ld ZHONG ; William Wei Liang PEH ; Wai Ching LAM ; Kenneth MAK ; Shih-Hui LIM
Annals of the Academy of Medicine, Singapore 2025;54(8):491-497
INTRODUCTION:
While traditional Chinese medicine (TCM) has a long history and continues to be widely practised, its overall clinical efficacy according to conventional scientific standards remains the topic of ongoing research and exploration. This review focuses on the potential use of acupuncture and Chinese herbal medicine (CHM) in combination with Western medicine in Singapore, based on recently published data on the clinical effectiveness and cost-effectiveness of these TCM treatments.
METHOD:
We collated and summarised 71 research papers published in the past decade, focusing on randomised controlled trials, systematic reviews and population-based cohort studies that had a total sample size (treatment and control arms) exceeding 60. English-language articles published between 2015 and 2025 were identified by searching PubMed/MEDLINE, the Cochrane Library and the China National Knowledge Infrastructure. The search strategy included intervention terms like "acupuncture", "Chinese medicine", "TCM", "traditional Chinese medicine", "RCT" and "randomized controlled trial"; economic evaluation terms like "cost" and "cost-effectiveness"; and disease conditions of concern. We narrowed our research to the clinical effectiveness and cost-effectiveness of CHM in which either the individual ingredients or the products were listed as Chinese Proprietary Medicines (CPMs).
RESULTS:
The summary tables demonstrate that the integration of acupuncture and/or CPMs with conventional Western medicine can enhance treatment outcomes across various chronic and non-chronic diseases. Their affordability and preventive focus can contribute to long-term healthcare cost savings, benefiting both patients and the healthcare system as a whole.
CONCLUSION
With a robust regulatory framework, scientific validation and government support, acupunc-ture and CPMs have an important role in the management of various diseases, especially chronic ones, in Singapore.
Humans
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Singapore
;
Medicine, Chinese Traditional/methods*
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Acupuncture Therapy/methods*
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Drugs, Chinese Herbal/economics*
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Cost-Benefit Analysis
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Disease Management
2.Changing models of care for emergency surgical and trauma patients in Singapore.
Sachin MATHUR ; Tiong Thye GOO ; T'zu Jen TAN ; Kok Yang TAN ; Kenneth Seck Wai MAK
Singapore medical journal 2016;57(6):282-286
The last 15 years have seen changing patterns of injury in emergency surgery and trauma patients. The ability to diagnose, treat and manage these patients nonoperatively has led to a decline in interest in trauma surgery as a career. In addition, healthcare systems face multiple challenges, including limited resources, an ageing population and increasing subspecialisation of medical care, while maintaining government-directed standards and managing public expectations. In the West, these challenges have led to the emergence of a new subspecialty, 'acute care surgery', with some models of care providing dedicated acute surgical units or separating acute and elective streams with the existing manpower resources. The outcomes for emergency surgery patients and efficiency gains are promising. In Singapore, Khoo Teck Puat Hospital has implemented its first dedicated acute surgical unit. This article outlines the evolution of acute care surgery and its relevance to Asia.
Critical Care
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trends
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Emergency Medicine
;
trends
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Health Plan Implementation
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Health Services Research
;
Hospitals
;
Humans
;
Models, Organizational
;
Outcome Assessment (Health Care)
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Patient Admission
;
Physicians
;
Singapore
;
Trauma Centers
;
organization & administration
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Wounds and Injuries
;
surgery
4.Successful nutritional therapy for superior mesenteric artery syndrome.
Dedrick Kok Hong CHAN ; Kenneth Seck Wai MAK ; Yee Lee CHEAH
Singapore medical journal 2012;53(11):e233-6
Superior mesenteric artery (SMA) syndrome is an uncommon cause of duodenal outlet obstruction. Symptoms and signs suggestive of this condition are nonspecific, and a high index of suspicion coupled with appropriate imaging studies are necessary for diagnosis. We present the case of a 70-year-old man who developed SMA syndrome following prolonged hospitalisation for a surgically treated bleeding duodenal ulcer. His SMA syndrome resolved after successful nonoperative management based on accepted guidelines for nutritional therapy, thus avoiding the need for reoperation and its attendant risks in a malnourished patient.
Aged
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Duodenal Obstruction
;
drug therapy
;
Duodenal Ulcer
;
complications
;
surgery
;
Endoscopy
;
Hospitalization
;
Humans
;
Male
;
Malnutrition
;
Nutrition Therapy
;
methods
;
Refeeding Syndrome
;
diagnosis
;
Superior Mesenteric Artery Syndrome
;
diet therapy
;
Treatment Outcome
5.Expanding the donor pool for liver transplantation in the setting of an "opt-out" scheme: 3 years after new legislation.
Victor T W LEE ; Chan Chung YIP ; Iyer Shridhar GANPATHI ; Stephen CHANG ; Kenneth S W MAK ; K PRABHAKARAN ; Krishnakumar MADHAVAN
Annals of the Academy of Medicine, Singapore 2009;38(4):315-317
INTRODUCTIONThe revised Human Organ Transplant Act (HOTA) was implemented in Singapore in July 2004. We aim to evaluate expanding the potential donor pool for liver transplant in Singapore with the inclusion of marginal donors.
MATERIALS AND METHODSAll donor referrals between July 2004 and June 2007 were studied. All potential deceased liver donors were heart-beating. After being reviewed by the transplant coordinator, potential donors were assessed by a transplant hepatologist and a transplant surgeon for suitability of organ donation strictly based on the programme's donor assessment protocol. Reasons for rejection as potential donors were documented. The clinical characteristics of all donor referrals were retrospectively reviewed, and an independent decision was made as to whether liver retrieval in each rejected case might have been possible.
RESULTSAmong the 128 potential donor referrals, 20 donors (15.6%) underwent liver retrieval. Of the 20 livers retrieved, 16 were implanted and 4 were not implanted (3 unfit recipients, and 1 donor liver with 40% steatosis). Another 10 donor livers were assessed intraoperatively and were rejected because of varying levels of steatosis. Of these livers assessed, 5 donor livers had steatosis <40% and 5 had steatosis >40%. Of the remaining potential donors, 45 were deemed not possible because of prolonged hypotension (9), on-going or unresolved sepsis (13), high-risk behaviour (4), non-actualisation (8), or pre-existing medical conditions (11). Another 53 donors may potentially have been suitable donors but were rejected because of possible sepsis (13), no suitable recipients (12), transient hypotension (10), transient abnormal liver function test (6), history of alcohol ingestion (5), non-actualisation because of consent (4) and other reasons (3). Overall, it was deemed that 61 donors (47.7%) might potentially have been suitable liver donors.
CONCLUSIONSDespite new legislation (HOTA) in Singapore, the utilisation of cadaveric donor livers showed no increase in the last 3 years. By expanding our donor criteria to include marginal donors, we could potentially increase the availability of deceased donor livers to meet our waiting list demands.
Adult ; Female ; Humans ; Liver Transplantation ; Living Donors ; legislation & jurisprudence ; supply & distribution ; Male ; Middle Aged ; Referral and Consultation ; organization & administration ; Retrospective Studies ; Singapore ; Tissue and Organ Procurement ; legislation & jurisprudence ; Waiting Lists

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