1.The relationship between fat attenuation index of pericoronary adipose tissue and coro-nary slow flow
Aixia LIANG ; Jingwu WANG ; Min XU ; Qian WANG ; Kelu SUN
Chinese Journal of Arteriosclerosis 2025;33(10):864-869
Aim To investigate the relationship between fat attenuation index(FAI)of pericoronary adipose tis-sue and coronary slow flow(CSF).Methods The clinical data of 135 hospitalized patients who underwent coronary angiography(CAG)due to chest tightness,chest pain and other similar symptoms from November 2023 to July 2024 were retrospectively collected.According to the blood flow grading criteria,the patients were divided into CSF group(n=61)and normal blood flow group(n=74).The basic information of the patients,the laboratory test results on the day of ad-mission and the data of coronary CT angiography(CCTA)were also collected.Multivariate Logistic regression was used to analyze the risk factors for CSF.The receiver operating characteristic(ROC)curve was used to evaluate the efficacy of FAI in predicting CSF.Results The white blood cell count(WBC),fasting blood glucose(FBG),high-sensitivity C-reactive protein(hs-CRP),interleukin-6(IL-6)and right coronary artery(RCA)FAI in the CSF group were 1.23,1.10,1.33 1.53 and 1.13 times that of those in the normal blood flow group,respectively(P<0.05).The left ventricu-lar ejection fraction(LVEF)in the CSF group was 94.78%of the normal blood flow group(P<0.05).Multivariate Lo-gistic regression analysis showed that elevated WBC(OR=1.891),elevated FBG(OR=1.774),decreased LVEF(OR=0.094),elevated hs-CRP increased(OR=1.124),increased RCA-FAI(OR=1.077)were independent risk factors for CSF(P<0.05).The results of ROC curve analysis showed that the area under the curve(AUC)of RCA-FAI in predic-ting CSF was 0.715(95%CI:0.627~0.802),the optimal cut-off value was-81.5 HU,the sensitivity was 0.803,and the specificity was 0.581.Conclusion Elevated WBC,elevated FBG,decreased LVEF,increased hs-CRP,and in-creased RCA-FAI are risk factors for CSF.Among them,RCA-FAI has a good efficacy in predicting the occurrence of CSF,which can be used to identify high-risk CSF patients as early as possible and reduce the incidence of CSF.
2.The relationship between fat attenuation index of pericoronary adipose tissue and coro-nary slow flow
Aixia LIANG ; Jingwu WANG ; Min XU ; Qian WANG ; Kelu SUN
Chinese Journal of Arteriosclerosis 2025;33(10):864-869
Aim To investigate the relationship between fat attenuation index(FAI)of pericoronary adipose tis-sue and coronary slow flow(CSF).Methods The clinical data of 135 hospitalized patients who underwent coronary angiography(CAG)due to chest tightness,chest pain and other similar symptoms from November 2023 to July 2024 were retrospectively collected.According to the blood flow grading criteria,the patients were divided into CSF group(n=61)and normal blood flow group(n=74).The basic information of the patients,the laboratory test results on the day of ad-mission and the data of coronary CT angiography(CCTA)were also collected.Multivariate Logistic regression was used to analyze the risk factors for CSF.The receiver operating characteristic(ROC)curve was used to evaluate the efficacy of FAI in predicting CSF.Results The white blood cell count(WBC),fasting blood glucose(FBG),high-sensitivity C-reactive protein(hs-CRP),interleukin-6(IL-6)and right coronary artery(RCA)FAI in the CSF group were 1.23,1.10,1.33 1.53 and 1.13 times that of those in the normal blood flow group,respectively(P<0.05).The left ventricu-lar ejection fraction(LVEF)in the CSF group was 94.78%of the normal blood flow group(P<0.05).Multivariate Lo-gistic regression analysis showed that elevated WBC(OR=1.891),elevated FBG(OR=1.774),decreased LVEF(OR=0.094),elevated hs-CRP increased(OR=1.124),increased RCA-FAI(OR=1.077)were independent risk factors for CSF(P<0.05).The results of ROC curve analysis showed that the area under the curve(AUC)of RCA-FAI in predic-ting CSF was 0.715(95%CI:0.627~0.802),the optimal cut-off value was-81.5 HU,the sensitivity was 0.803,and the specificity was 0.581.Conclusion Elevated WBC,elevated FBG,decreased LVEF,increased hs-CRP,and in-creased RCA-FAI are risk factors for CSF.Among them,RCA-FAI has a good efficacy in predicting the occurrence of CSF,which can be used to identify high-risk CSF patients as early as possible and reduce the incidence of CSF.
3.Analysis of chronic heart failure of coronary heart disease and ventricular arrhythmia
Kelu SUN ; Aixia LIAN ; Min XU ; Jingwu WANG ; Binbin LI
Chinese Journal of Primary Medicine and Pharmacy 2015;(5):699-701
Objective To analyze the treatment and pathogenetic condition of chronic heart failure of coro -nary heart disease(CHD) and ventricular arrhythmia (VA).Methods 100 patients with chronic heart failure were collected to observe the treatment of chronic heart failure and pathogenetic condition of VA .Results 44 cases occured VA and 56 cases without VA in 100 patients.NT-proBNP(3 110.00 ±522.00)pg/mL of VA group was sig-nificantly higher than that (2 200.00 ±486.00)pg/mL of non-VA group(t=8.996,P<0.05).LVEF(0.25 ± 0.08) of VA group was lower than that of non -VA group(0.41 ±0.98) (t=11.625,P<0.05).The occurrence (100.00%) of premature ventricular contraction ( PVC) of ≥70mm group in left ventricular internal diameter (LVID) was higher than that of 60 -69mm group (60.87%),50 -59mm group (37.04%),40 -49mm group
(15.38%) with statistically significant(χ2 =5.853,12.532,27.375,all P<0.05).The amount(44.20 ±12.90)mg of use βreceptor blockers of amiodarone group was significantly lower than that of non -amiodarone group(44.20 ± 12.90)mg (t=5.284,P<0.05).Conclusion NT-proBNP of CHEF of CHD and VA patients will improve and amiodarone can reduce the amount of use anti -heart failure drug .
4.Influence of right ventricular inlet septum pacing on heart function
Baoming ZOU ; Jingwu WANG ; Min XU ; Kelu SUN ; Li WANG
Chinese Journal of Postgraduates of Medicine 2010;33(1):27-29
Objective To investigate the changes of heart function after pacing in right ventricular inlet septum(RVIS) and right ventricular apex(RVA). Methods VVI pacing was performed in 64 patients who were randomly divided into two groups: RVIS group (33 patients) and RVA group (31 patients). The changes of serum brain natriuretic peptide (BNP),pacing parameters and QRS interval were assessed in 24 hours, 3 months and 1 year after the ventricle was paced effectively. Results When the ventricle was paced effectively,the pacing parameters,including voltage threshold and electrode impedance were similar in different stages between the two groups. In 24 hours, 3 months and 1 year after the ventricle was paced effectively,the QRS interval in RVIS group were obviously narrower than those in RVA group [( 128.0±28.6 ) ms vs ( 150.0 ± 37.1 ) ms, ( 131.0±21.5 ) ms vs ( 153.0 ±28.5 ) ms, ( 130.0 ±19.7 ) ms vs ( 155.0±20.2) ms, P < 0.05 ]. After treatment, the level of serum BNP increased significantly in two groups. The BNP level in R VIS group was significantly lower than that in RVA group (P < 0.05). Conclusion The R VIS pacing is not only as safe and effective as RVA pacing, but also is more consistent with the physiological ventricular activation sequence.

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