Intravenous thrombolysis before endovascular thrombectomy has become the standard treatment for acute ischemic stroke caused by anterior circulation large vessel occlusion.However,there is still controversy about direct endovascular thrombectomy or bridging intravenous thrombolysis.This article elaborates on this.

With the widespread use of statins, they significantly reduce the risk of ischemic stroke, and are even expected to improve functional outcomes in patients with ischemic stroke. However, there are many problems to be clarified in the treatment and prevention of ischemic stroke with statins in clinical practice. This article discusses this.

Duetothepatientswithintracerebralhemorrhageusualypresenttheriskfactorsfor ischemic stroke, the survivors after intracerebral hemorrhage are usualy facing a high risk of recurrent intracerebral hemorrhage or ischemic stroke at the same time. There is alw ays controversy about w hether these patients should be treated w ith antiplatelet therapy. This article introduces the different point of view s of researchers.

Thisarticleintroducesthedifferentperspectivesonwhetherusingcarotidendarterectomy or intensifying the optimal medical therapy alone in recurrent stroke prevention practice in patients w ith symptomatic carotid stenosis.

Traditionally,delayed cerebral ischemia after subarachnoid hemorrhage is caused by cerebral vasospasm.A large number of studies have been conducted for the prevention and treatment of cerebral vasospasm in order to try to improve the clinical outcomes after subarachnoid hemorrhage.However,for the treatment of cerebral vasospasm does not fundamentally reduce disability and mortality after subarachnoid hemorrhage.While researchers suspect whether the delayed cerebral ischemia is associated with cerebral vasospasm,they begin to question whether prevention of cerebral vasospasm can improve clinical outcomes after subarachnoid hemorrhage.This article analyzes this.

Intracranial aneurysm rupture can result in life-threatening subarachnoid hemorrhage.There is no doubt about the treatment of patients with symptomatic intracranial arterial aneurysms,but whether the patients with asymptomatic intracranial aneurysms ＜ 7 mm in diameter should be treated with conservative treatment,implementation of clipping or endovascular coil embolization remain controversy.This article discusses about this.

The efficacy of statins in the prevention of ischemic stroke has been confirmed,but whether it will increase the risk of intracerebral hemorrhage has not been determined.For patients receiving long-term statin therapy should continue or discontinue statin therapy after suffering from intracerebral hemorrhage remains controversy.This article discusses about it.

There are many controversies for how to treat the occurrence of ischemic stroke on the basis of infective endocarditis would be more reasonable,especially there is no consensus on whether to treat with anticoagulants.The article discusses about this.

Statin therapy has become a standard method for the prevention of ischemic stroke,and is becoming a treatment option for acute ischemic stroke.The pleiotropic effects of statins which are independent of cholesterol are the main basis of using them in the treatment of ischemic stroke.It is regarded that these pleiotropic effects may have neuroprotective effects,thus improving the neurological functional outcome of patients.At the same time,studies have shown that the therapeutic effect of statins has dose-dependent manner; therefore,we advocate using high-dose statin therapy.However,about whether high-dose statins should be used in patients with ischemic stroke of the different mechanisms remain controversial.

With the continuous improvement of drag for stroke prevention, ipsilateral stroke risk in patients with asymptomatic carotid stenosis has been equal to or lower than that in the revascularization group in randomized controlled trials. Under this condition, is the asymptomatic severe carotid stenosis an indication for revascularization? This article introduces the views of different researchers.