1.Observation of pulmonary arterial pressure index of military personnel stationed on plateau
Mei XU ; Kechun YAO ; Xiaoyan FAN ; Xuemei WANG ; Lamu PUBU ; Xi LIU
Chinese Journal of Aerospace Medicine 2021;32(4):226-229
Objective:To provide the reference for aeromedical support to long-distance delivery to plateau by comparing the changes of pulmonary artery pressure and right heart correlation parameters of military personnel between the states of pre-entering and different time periods on plateau.Methods:The correlation indexes on pulmonary artery pressure of 23 healthy military personnel were measured before and after entering plateau, including blood flow acceleration time (ACT) of pulmonary artery, right ventricular ejection time (RVET) and right ventricular pre-ejection period (RVPEP). The systolic pulmonary artery pressure (SPAP) and mean pulmonary artery pressure (MPAP) were calculated. The right ventricular outflow tract (RVOT), main pulmonary artery diameter (MPAD), right ventricular diameter (RVD) and right atrium diameter (RAD) were measured. According to the different stationed time, the military personnel were divided into 3 groups: 10 cases for 2 months, 7 cases for 3 months and 6 cases for 8 months. The changes of pulmonary artery pressure of military personnel were compared among the different time periods, as well as before and after stationed on plateau for each group that distinguished the states on plain and plateau.Results:After entering plateau, ACT of subjects was significantly reduced ( F=3.25, P<0.01), RVPEP was increased, the difference was significant ( F=4.51, P<0.05), SPAP and MPAP were significantly increased, and the differences were statistically significant ( F=4.19, 2.69, P<0.01). Two months after entering plateau, ROVT and RVD of subjects were significantly increased ( t=1.442, 2.643, P<0.05), but the MPAD and RAD were not different as compared those before entering plateau (P>0.05). Conclusions:① The hypoxic and low-pressure in plateau areas cause the significantly higher pulmonary artery pressure of military personnel than that in plain areas, and the right ventricular structure is also changed accordingly. ② The pulmonary artery pressure shows insignificant difference with the progresses of body adaptation and the time stationed on plateau. ③ Pulmonary hypertension occurs in the early stage of stationing on plateau. So preventing or alleviating the occurrence of pulmonary hypertension at the early stage of plateau stationing is important for the military personnel assigned via air delivery.
2.Observation of pulmonary arterial pressure index of military personnel stationed on plateau
Mei XU ; Kechun YAO ; Xiaoyan FAN ; Xuemei WANG ; Lamu PUBU ; Xi LIU
Chinese Journal of Aerospace Medicine 2021;32(4):226-229
Objective:To provide the reference for aeromedical support to long-distance delivery to plateau by comparing the changes of pulmonary artery pressure and right heart correlation parameters of military personnel between the states of pre-entering and different time periods on plateau.Methods:The correlation indexes on pulmonary artery pressure of 23 healthy military personnel were measured before and after entering plateau, including blood flow acceleration time (ACT) of pulmonary artery, right ventricular ejection time (RVET) and right ventricular pre-ejection period (RVPEP). The systolic pulmonary artery pressure (SPAP) and mean pulmonary artery pressure (MPAP) were calculated. The right ventricular outflow tract (RVOT), main pulmonary artery diameter (MPAD), right ventricular diameter (RVD) and right atrium diameter (RAD) were measured. According to the different stationed time, the military personnel were divided into 3 groups: 10 cases for 2 months, 7 cases for 3 months and 6 cases for 8 months. The changes of pulmonary artery pressure of military personnel were compared among the different time periods, as well as before and after stationed on plateau for each group that distinguished the states on plain and plateau.Results:After entering plateau, ACT of subjects was significantly reduced ( F=3.25, P<0.01), RVPEP was increased, the difference was significant ( F=4.51, P<0.05), SPAP and MPAP were significantly increased, and the differences were statistically significant ( F=4.19, 2.69, P<0.01). Two months after entering plateau, ROVT and RVD of subjects were significantly increased ( t=1.442, 2.643, P<0.05), but the MPAD and RAD were not different as compared those before entering plateau (P>0.05). Conclusions:① The hypoxic and low-pressure in plateau areas cause the significantly higher pulmonary artery pressure of military personnel than that in plain areas, and the right ventricular structure is also changed accordingly. ② The pulmonary artery pressure shows insignificant difference with the progresses of body adaptation and the time stationed on plateau. ③ Pulmonary hypertension occurs in the early stage of stationing on plateau. So preventing or alleviating the occurrence of pulmonary hypertension at the early stage of plateau stationing is important for the military personnel assigned via air delivery.
3.A long term follow-up study on the nonsurgical therapy of abdominal aortic aneurysm in senile patients
Longfang ZHANG ; Kechun YAO ; Xiaohong WANG
Medical Journal of Chinese People's Liberation Army 2001;0(12):-
Objective To study the course of development of aneurysm of abdominal aorta (AAA) with nonsurgical treatment in senile patients. Methods 37 subjects were included in the study, and they were divided into 3 groups according to the size of aneurysm observed at the first visit. The diameter of aneurysm was measured, and the measurement was repeated at periodic follow up. The yearly increase of the diameter was calculated and analyzed. Results For the 37 patients, the AAA mean diameter was 4.68cm at the first visit. The period of follow-up was 0.5 to 11 years, with a mean of 6.1 years. The average yearly increase in tumor diameter was 0.47cm/year. 14 patients with aneurysm diameter of 6.0cm had an average increase of 0.67cm/year. 5 patients died during the follow-up period, 2 of them died of rupture of the aneurysm, the diameter of which was 8.35cm and 8.91cm, respectively. Endoaneurysmorrhaphy with stent was performed in 7 patients. Conclusion The size of AAA in the senile patients increased slowly if the aneurysm diameter is 6.0 cm, the tumor size might increase quickly, and active intervention is recommended.
4.The relationships between Ultrasonographic Features and the Expression of estrogen receptor and progesterone receptor in Postmenopausal Women with Infiltrating Ductal Carcinoma of Breast
Longfang ZHANG ; Kechun YAO ; Na WANG
Medical Journal of Chinese People's Liberation Army 1981;0(06):-
Objective To investigate the relationships between of 2-dimensional (2D) and color Doppler ultrasonographic features and the expressions of both estrogen receptor (ER) and progesterone receptor (PR) in postmenopausal women with infiltrating ductal carcinoma (IDC) in breast, and to evaluate the feasibility of predicting the expressions of ER and PR in IDC by means of ultrasonographic features. Methods The clinical data of 96 patients with breast infiltrating ductal carcinoma diagnosed by pathology during Jun. 2002 to Jun. 2007 were retrospectively analyzed. The correlation between ultrasonographic features and both ER and PR expressions in the mastectomy specimens determined by immunohistochemical technique was statistically analyzed. Results Of the 96 cases, the positive expression rates of ER and PR were 54.17% and 50%, respectively, the bi-positive and bi-negative expression rates of ER and PR were 41.67% and 37.5%, respectively. Among the breast carcinoma, the positive expression rate of ER was higher in tumor with ultrasonographic spicule sign (P

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