1.Evaluating the Longitudinal Efficacy of Suicide CARE (a Korean Standard Gatekeeper Training Program) in a General Community Sample: A Randomized Controlled Trial
Jinmi SEOL ; Hwa-Young LEE ; Sang Min LEE ; Seon Wan KI ; Sung Joon CHO ; Kang Seob OH ; Jong-Woo PAIK
Psychiatry Investigation 2024;21(12):1329-1337
Objective:
Suicide poses a significant public health concern with increasing prevalence in the general population, emphasizing the need for effective gatekeeper suicide prevention education. This study assesses the longitudinal effectiveness of the “Suicide CARE” gatekeeper training program within a general community sample. Suicide CARE is representative gatekeeper program in Korea. A total of 5 million individuals completed the training program of Suicide CARE in Korea to date.
Methods:
Participants were recruited through the Korea Suicide Prevention Association website, randomly assigned to the experimental (n=49) or control group (n=53). Pre- and post-training surveys, along with a 3-month follow-up, measured perceived knowledge, gatekeeper efficacy, preparedness, and attitudes toward suicide. Longitudinal effects were analyzed using repeated measures analysis of variance.
Results:
The experimental group showed significant improvement in perceived knowledge, gatekeeper efficacy, perceived preparedness, and some aspects of attitude towards suicide compared to the control group, with effects declining over time but remaining statistically significant at the 3-month follow-up test.
Conclusion
This study is the first to evaluate the longitudinal effectiveness of Suicide CARE in a community population. Strategic integration of evidence-based gatekeeper training programs like Suicide CARE can contribute to community suicide prevention initiatives.
2.The Moderating Effect of Resilience on the Relationship Between the Relevance to Victims With Post-Trauma Psychiatric Symptoms of Community Residents After Seoul Halloween Crowd Crush
Se Youl KIM ; Sra JUNG ; Mi Yeon LEE ; Kang-Seob OH ; Young-Chul SHIN ; Dong-Won SHIN ; Junhyung KIM ; Eun Soo KIM ; Sun Wook JUNG ; Kwang-yeol LEE ; Nahyun OH ; Sung Joon CHO ; Sang-Won JEON
Psychiatry Investigation 2024;21(11):1183-1192
Objective:
This study aimed to examine the psychiatric impact of the Seoul Halloween crowd crush on individuals related to the victims compared to the general population. It also explores the moderating effect of resilience on the relationship between trauma exposure and psychiatric symptoms.
Methods:
In total, 2,220 participants completed various post-incident questionnaires (Patient Health Questionnaire-9, Generalized Anxiety Disorder-7, Hwa-byung symptom scale, post-traumatic stress disorder checklist for DSM-5, and Brief Resilience Scale) 30 days after the incident. Moderation analyses were conducted using the PROCESS macro in the statistical package for the social sciences.
Results:
Individuals related to the victims exhibited higher symptom severity and a greater risk for clinically significant levels of depression, anxiety, anger, and post-traumatic stress disorder (PTSD) (odds ratio=3.28, 3.33, 1.51, and 4.39 respectively). The impact of relevance to victims on anxiety and PTSD symptoms was moderated by resilience, with a stronger effect observed for individuals with low resilience (β=3.51, 95% confidence interval [CI] 2.78–4.24 for anxiety and β=14.53, 95% CI 12.43–16.63 for PTSD) than for those with high resilience (β=1.69, 95% CI 0.72–2.65 for anxiety and β=8.33, 95% CI 5.56–11.09 for PTSD).
Conclusion
When related to the victims, it was found that not only PTSD, but also depression, anxiety, and anger could intensify. Resilience emerged as a potential buffer against these adverse effects, emphasizing its significance in mitigating the psychiatric impact of community trauma.
3.Clinical Burden of Aripiprazole Once-Monthly in Patients With Schizophrenia Receiving Antipsychotic Polypharmacy
Jiwan MOON ; Hyeryun YANG ; Sra JUNG ; Soo Bong JUNG ; Jhin-Goo CHANG ; Won-Hyoung KIM ; Sang Min LEE ; Jangrae KIM ; Minji BANG ; Min-Kyoung KIM ; Eun Soo KIM ; Dong-Won SHIN ; Kang Seob OH ; Sang Won JEON ; Junhyung KIM ; Young Chul SHIN ; Sung Joon CHO
Journal of the Korean Society of Biological Psychiatry 2024;31(2):34-39
Objectives:
This study aimed to assess the clinical burden, a critical determinant of medication adherence in patients with schizophrenia, after the administration of Aripiprazole once-monthly (AOM).
Methods:
This study was a retrospective, non-interventional, multicenter, naturalistic observational study conducted through the analysis of participants’ electronic medical records. Study participants were recruited from eight sites. Data were collected at baseline, defined as the time of AOM administration, and at 1, 3, 6, 9, and 12 months thereafter. The primary outcome measure was the change in the Clinical Global Impression-Clinical Benefit (CGI-CB) score over 12 months, and the secondary outcome measure was the change in the Clinical Global Impression-Improvement (CGI-I) score.
Results:
The data of 139 participants were analyzed, revealing a statistically significant decrease of 26.8% in CGI-CB scores and 13.4% in CGI-I scores over 12 months. Upon comparison between adjacent visit intervals, significant reductions were observed for both measures between month 3 and month 6.
Conclusions
This study is the first multicenter investigation to simultaneously evaluate the clinical efficacy and tolerability of transitioning to AOM in the context of polypharmacy. The study suggested that AOM may contribute to reducing the clinical burden, thereby improving the quality of life for patients with schizophrenia.
4.Evaluating the Longitudinal Efficacy of Suicide CARE (a Korean Standard Gatekeeper Training Program) in a General Community Sample: A Randomized Controlled Trial
Jinmi SEOL ; Hwa-Young LEE ; Sang Min LEE ; Seon Wan KI ; Sung Joon CHO ; Kang Seob OH ; Jong-Woo PAIK
Psychiatry Investigation 2024;21(12):1329-1337
Objective:
Suicide poses a significant public health concern with increasing prevalence in the general population, emphasizing the need for effective gatekeeper suicide prevention education. This study assesses the longitudinal effectiveness of the “Suicide CARE” gatekeeper training program within a general community sample. Suicide CARE is representative gatekeeper program in Korea. A total of 5 million individuals completed the training program of Suicide CARE in Korea to date.
Methods:
Participants were recruited through the Korea Suicide Prevention Association website, randomly assigned to the experimental (n=49) or control group (n=53). Pre- and post-training surveys, along with a 3-month follow-up, measured perceived knowledge, gatekeeper efficacy, preparedness, and attitudes toward suicide. Longitudinal effects were analyzed using repeated measures analysis of variance.
Results:
The experimental group showed significant improvement in perceived knowledge, gatekeeper efficacy, perceived preparedness, and some aspects of attitude towards suicide compared to the control group, with effects declining over time but remaining statistically significant at the 3-month follow-up test.
Conclusion
This study is the first to evaluate the longitudinal effectiveness of Suicide CARE in a community population. Strategic integration of evidence-based gatekeeper training programs like Suicide CARE can contribute to community suicide prevention initiatives.
5.The Moderating Effect of Resilience on the Relationship Between the Relevance to Victims With Post-Trauma Psychiatric Symptoms of Community Residents After Seoul Halloween Crowd Crush
Se Youl KIM ; Sra JUNG ; Mi Yeon LEE ; Kang-Seob OH ; Young-Chul SHIN ; Dong-Won SHIN ; Junhyung KIM ; Eun Soo KIM ; Sun Wook JUNG ; Kwang-yeol LEE ; Nahyun OH ; Sung Joon CHO ; Sang-Won JEON
Psychiatry Investigation 2024;21(11):1183-1192
Objective:
This study aimed to examine the psychiatric impact of the Seoul Halloween crowd crush on individuals related to the victims compared to the general population. It also explores the moderating effect of resilience on the relationship between trauma exposure and psychiatric symptoms.
Methods:
In total, 2,220 participants completed various post-incident questionnaires (Patient Health Questionnaire-9, Generalized Anxiety Disorder-7, Hwa-byung symptom scale, post-traumatic stress disorder checklist for DSM-5, and Brief Resilience Scale) 30 days after the incident. Moderation analyses were conducted using the PROCESS macro in the statistical package for the social sciences.
Results:
Individuals related to the victims exhibited higher symptom severity and a greater risk for clinically significant levels of depression, anxiety, anger, and post-traumatic stress disorder (PTSD) (odds ratio=3.28, 3.33, 1.51, and 4.39 respectively). The impact of relevance to victims on anxiety and PTSD symptoms was moderated by resilience, with a stronger effect observed for individuals with low resilience (β=3.51, 95% confidence interval [CI] 2.78–4.24 for anxiety and β=14.53, 95% CI 12.43–16.63 for PTSD) than for those with high resilience (β=1.69, 95% CI 0.72–2.65 for anxiety and β=8.33, 95% CI 5.56–11.09 for PTSD).
Conclusion
When related to the victims, it was found that not only PTSD, but also depression, anxiety, and anger could intensify. Resilience emerged as a potential buffer against these adverse effects, emphasizing its significance in mitigating the psychiatric impact of community trauma.
6.Evaluating the Longitudinal Efficacy of Suicide CARE (a Korean Standard Gatekeeper Training Program) in a General Community Sample: A Randomized Controlled Trial
Jinmi SEOL ; Hwa-Young LEE ; Sang Min LEE ; Seon Wan KI ; Sung Joon CHO ; Kang Seob OH ; Jong-Woo PAIK
Psychiatry Investigation 2024;21(12):1329-1337
Objective:
Suicide poses a significant public health concern with increasing prevalence in the general population, emphasizing the need for effective gatekeeper suicide prevention education. This study assesses the longitudinal effectiveness of the “Suicide CARE” gatekeeper training program within a general community sample. Suicide CARE is representative gatekeeper program in Korea. A total of 5 million individuals completed the training program of Suicide CARE in Korea to date.
Methods:
Participants were recruited through the Korea Suicide Prevention Association website, randomly assigned to the experimental (n=49) or control group (n=53). Pre- and post-training surveys, along with a 3-month follow-up, measured perceived knowledge, gatekeeper efficacy, preparedness, and attitudes toward suicide. Longitudinal effects were analyzed using repeated measures analysis of variance.
Results:
The experimental group showed significant improvement in perceived knowledge, gatekeeper efficacy, perceived preparedness, and some aspects of attitude towards suicide compared to the control group, with effects declining over time but remaining statistically significant at the 3-month follow-up test.
Conclusion
This study is the first to evaluate the longitudinal effectiveness of Suicide CARE in a community population. Strategic integration of evidence-based gatekeeper training programs like Suicide CARE can contribute to community suicide prevention initiatives.
7.The Moderating Effect of Resilience on the Relationship Between the Relevance to Victims With Post-Trauma Psychiatric Symptoms of Community Residents After Seoul Halloween Crowd Crush
Se Youl KIM ; Sra JUNG ; Mi Yeon LEE ; Kang-Seob OH ; Young-Chul SHIN ; Dong-Won SHIN ; Junhyung KIM ; Eun Soo KIM ; Sun Wook JUNG ; Kwang-yeol LEE ; Nahyun OH ; Sung Joon CHO ; Sang-Won JEON
Psychiatry Investigation 2024;21(11):1183-1192
Objective:
This study aimed to examine the psychiatric impact of the Seoul Halloween crowd crush on individuals related to the victims compared to the general population. It also explores the moderating effect of resilience on the relationship between trauma exposure and psychiatric symptoms.
Methods:
In total, 2,220 participants completed various post-incident questionnaires (Patient Health Questionnaire-9, Generalized Anxiety Disorder-7, Hwa-byung symptom scale, post-traumatic stress disorder checklist for DSM-5, and Brief Resilience Scale) 30 days after the incident. Moderation analyses were conducted using the PROCESS macro in the statistical package for the social sciences.
Results:
Individuals related to the victims exhibited higher symptom severity and a greater risk for clinically significant levels of depression, anxiety, anger, and post-traumatic stress disorder (PTSD) (odds ratio=3.28, 3.33, 1.51, and 4.39 respectively). The impact of relevance to victims on anxiety and PTSD symptoms was moderated by resilience, with a stronger effect observed for individuals with low resilience (β=3.51, 95% confidence interval [CI] 2.78–4.24 for anxiety and β=14.53, 95% CI 12.43–16.63 for PTSD) than for those with high resilience (β=1.69, 95% CI 0.72–2.65 for anxiety and β=8.33, 95% CI 5.56–11.09 for PTSD).
Conclusion
When related to the victims, it was found that not only PTSD, but also depression, anxiety, and anger could intensify. Resilience emerged as a potential buffer against these adverse effects, emphasizing its significance in mitigating the psychiatric impact of community trauma.
8.Clinical Burden of Aripiprazole Once-Monthly in Patients With Schizophrenia Receiving Antipsychotic Polypharmacy
Jiwan MOON ; Hyeryun YANG ; Sra JUNG ; Soo Bong JUNG ; Jhin-Goo CHANG ; Won-Hyoung KIM ; Sang Min LEE ; Jangrae KIM ; Minji BANG ; Min-Kyoung KIM ; Eun Soo KIM ; Dong-Won SHIN ; Kang Seob OH ; Sang Won JEON ; Junhyung KIM ; Young Chul SHIN ; Sung Joon CHO
Journal of the Korean Society of Biological Psychiatry 2024;31(2):34-39
Objectives:
This study aimed to assess the clinical burden, a critical determinant of medication adherence in patients with schizophrenia, after the administration of Aripiprazole once-monthly (AOM).
Methods:
This study was a retrospective, non-interventional, multicenter, naturalistic observational study conducted through the analysis of participants’ electronic medical records. Study participants were recruited from eight sites. Data were collected at baseline, defined as the time of AOM administration, and at 1, 3, 6, 9, and 12 months thereafter. The primary outcome measure was the change in the Clinical Global Impression-Clinical Benefit (CGI-CB) score over 12 months, and the secondary outcome measure was the change in the Clinical Global Impression-Improvement (CGI-I) score.
Results:
The data of 139 participants were analyzed, revealing a statistically significant decrease of 26.8% in CGI-CB scores and 13.4% in CGI-I scores over 12 months. Upon comparison between adjacent visit intervals, significant reductions were observed for both measures between month 3 and month 6.
Conclusions
This study is the first multicenter investigation to simultaneously evaluate the clinical efficacy and tolerability of transitioning to AOM in the context of polypharmacy. The study suggested that AOM may contribute to reducing the clinical burden, thereby improving the quality of life for patients with schizophrenia.
9.Validation of the Korean Version of Geriatric Suicide Ideation Scale-Screen
Sihwang KIM ; Seonyoung PARK ; Jungae LEE ; Kang-Seob OH
Journal of Korean Geriatric Psychiatry 2024;28(2):25-32
Objective:
This study aims to validate the Korean version of Geriatric Suicide Ideation Scale-Screen (K-GSIS-Screen) and evaluate its clinical utility for screening suicidal ideation and risk among older adults across clinical and community settings.
Methods:
GSIS-Screen was translated into Korean and administered to 50 community-residing older adults and 49 elderly patients attending a depression clinic in the psychiatric department of a hospital. Reliability and validity were assessed by Cron-bach’s α and exploratory factor analysis. Then, clinical utility was further examined through receiver operating characteristic(ROC) curve analysis.
Results:
Exploratory factor analysis confirmed a single-factor structure. Overall findings demonstrated moderate to strong in-ternal consistency, convergent validity, and discriminant validity across community and clinical settings. Additionally, K-GSISScreen differentiated between older adults with and without suicidal ideation, with those in the former group scoring higher.ROC analysis confirmed an area under curve of 0.81.
Conclusion
The K-GSIS-Screen appears to be a useful primary screening tool for detecting suicidal ideation among older adults. It has the potential to facilitate rapid identification of suicidal ideation in clinical and community settings, thereby sup-porting early and appropriate interventions.
10.Gender Difference of Moderated Mediating Effect of Grit Between Occupational Stress and Suicidal Ideation in Korean Workers
Sra JUNG ; Hyejeong JEON ; Mi Yeon LEE ; Eunsoo KIM ; Dong-Won SHIN ; Young-Chul SHIN ; Kang-Seob OH ; Min-Kyoung KIM ; Sang-Won JEON ; Sung Joon CHO
Journal of Korean Medical Science 2024;39(50):e308-
Background:
This study examined gender differences in occupational stress, depressive symptoms, and suicidal ideation by considering the potential moderating effect of grit on Korean employees.
Methods:
A total of 11,369 participants (7,735 men and 3,634 women) aged 19–65 years, employed across 18 private companies and local government organizations in Korea, completed questionnaires including the Short Grit Scale, Korean Occupational Stress Scale, and Center for Epidemiologic Studies Depression Scale between April 2020 and March 2022.Suicidal ideation was assessed based on its presence or absence. Mediation and moderation analyses were performed using the Statistical Package for the Social Sciences PROCESS macro.
Results:
Depressive symptoms partially mediated the relationship between occupational stress and suicidal ideation in male employees, whereas depressive symptoms fully mediated the relationship in female employees. Grit moderated the relationship between depressive symptoms and suicidal ideation in male employees but not in female employees.Furthermore, the moderated mediating effect of grit in male employees on the relationship between occupational stress and suicidal ideation provided less protection in cases of severe depression. The cross-sectional design does not allow for causal inferences.
Conclusion
These findings contribute to understanding of the gender differences in the impact of depressive symptoms on the relationship between occupational stress and suicidal ideation, as well as the protective effect of grit. These findings highlight the need for genderspecific approaches to prevent suicidal ideation among employees.

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