1.Pathogenesis and Treatment of Cancer Therapy Induced Thrombocytopenia based on the Theory of 'Spleen Governing the Containment of Blood'
Fuwei XING ; Kaixin JI ; MIMAGONGLA ; Dongyu WANG ; Jiakun LI ; Yubo QI ; Yayue ZHANG
Journal of Traditional Chinese Medicine 2026;67(17):1835-1839
Based on the theory of 'spleen governing the containment of blood' in The Classic of Difficult Issues (《难经》), it is proposed that medication toxicity damaging the middle jiao (焦) and failure of the spleen to contain blood constitute the core pathogenesis of cancer therapy induced thrombocytopenia (CTIT). It is believed that the anti-tumor drug toxicity directly hits middle jiao, leading to spleen qi depletion, impairment of transportation and transformation, and insufficiency of the source of blood production. Consequently, the vessels and collaterals are deprived of nourishment and become structurally damaged. Blood fails to be contained and stored within the vessels, resulting in extravasation beyond the vascular system. Persistent retention of drug toxicity may further cause stasis due to blood deviating from its normal pathway and gradually consume the essence. In view of this root deficiency with branch excess, it is proposed that the treatment should focus on fortifying spleen, boosting qi and containing blood, with the aim of restoring spleen and stomach transportation functions, repairing vascular damage, and recovering the spleen's blood-containing function. According to individual syndrome patterns, prescriptions may be supplemented with herbs that stabilize vessels and consolidate collaterals, remove stasis and promote regeneration, and replenish essence and nourish marrow, providing new perspectives for the prevention and treatment of CTIT with traditional Chinese medicine.
2.Clinical observation of neck Gongfa exercise intervening people at high risk for cervical spondylosis
Ji MA ; Yu ZHANG ; Fei GU ; Yumin LIU ; Junliang WANG ; Cheng WANG ; Yazhou LI ; Kaixin SUN ; Jun ZHANG ; Jue HONG
Journal of Acupuncture and Tuina Science 2024;22(6):489-496
Objective:To observe the clinical efficacy of neck Gongfa exercise in intervening people at high risk for cervical spondylosis. Methods:A total of 212 participants from 8 companies at high risk for cervical spondylosis were divided into two groups using the random number table method,with 105 participants in the control group receiving health education and 107 participants in the trial group receiving an additional neck Gongfa exercise.After successive 3-month interventions,the two groups were compared in terms of cervical soft tissue tension and neck disability index(NDI)score.The incidence of cervical spondylosis was observed 3 months later. Results:During the process,10 cases dropped out in the trial group,and the control group had 9 dropout cases.After the intervention,the cervical soft tissue tension value and NDI score improved in both groups(P<0.05)and showed significant differences between the two groups(P<0.05).At the 3-month follow-up,the trial group had a lower incidence rate of cervical spondylosis than the control group(P<0.05). Conclusion:For people at high risk for cervical spondylosis,neck Gongfa exercise can effectively improve cervical soft tissue tension and motor dysfunction and lower the incidence of cervical spondylosis in the short run.

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