Objective:To explore the effects of mHealth-based home exercise rehabilitation on lower limb muscle strength and quality of life in liver cancer surgery patients after discharge from the hospital.Method:One hundred cases of hepatocellular carcinoma patients who underwent surgery in two tertiary hospi-tals from June 2022 to August 2023 were selected,including 50 cases in the control group and 50 cases in the intervention group.The patients were instructed to carry out home exercise for 3 weeks respectively.The control group was given a home rehabilitation exercise manual,while the intervention group developed mHealth-based exercise rehabilitation based on this exercise prescription.The muscle strength and quality of life levels of the two groups were compared after the intervention.Result:Patients with mHealth-based exercise rehabilitation had significantly higher lower limb muscle strength than the control group after 3 weeks of intervention(P<0.05).The fatigue and nausea,and vomiting symp-toms in the quality of life domains were significantly improved compared with the control group(P<0.05).Conclusion:Home-based exercise rehabilitation based on mHealth can effectively improve lower limb muscle strength,fatigue,and nausea and vomiting symptoms in patients discharged from the hospital after surgery for hepatocellular carcinoma.It is an effective way to improve the rehabilitation of patients discharged from the hospital for hepatocellular carcinoma.

Objective:To construct a management program for postoperative home exercise rehabilitation in patients undergoing liver cancer surgery, and to provide guidance for improving home exercise capacity after liver cancer surgery.Methods:A mixed study design was used to summarize the best evidence for a postoperative home exercise rehabilitation program for patients with liver cancer based on a literature review from January to June 2022, and the first draft of a postoperative home exercise rehabilitation program for liver cancer patients was formed after discussion in the research team, and discussed in an expert validation meeting, and the first draft of the program was revised and improved according to the expert′s opinion in combination with clinical practice.Results:This study included 14 articles, including 4 clinical guidelines, 3 systematic evaluations, 2 randomized controlled studies, 3 class experimental research and 2 expert consensuses. And 22 pieces of evidence were included in the summary of evidence, including the principle of exercise, supervision of exercise, type of exercise, time and frequency of exercise, and intensity of exercise. A total of 10 experts participated in the expert validation meeting, with 6 males and 4 females, aged (53.31 ± 10.23) years, with an expert authority coefficient of 0.944, and the final home exercise rehabilitation program for postoperative patients with liver cancer was formed to include six aspects, including pre-exercise assessment, warm-up exercise, whole-body exercise, stretching exercise, organizing exercise, and exercise detection and follow-up.Conclusions:The home exercise rehabilitation program for postoperative liver cancer surgery patients is scientific, practical and feasible, and it is a systematic, standardized and safe exercise management model, which can be used for home guidance of postoperative exercise rehabilitation for liver cancer patients.

Objective:To explore the effects of mHealth-based home exercise rehabilitation on lower limb muscle strength and quality of life in liver cancer surgery patients after discharge from the hospital.Method:One hundred cases of hepatocellular carcinoma patients who underwent surgery in two tertiary hospi-tals from June 2022 to August 2023 were selected,including 50 cases in the control group and 50 cases in the intervention group.The patients were instructed to carry out home exercise for 3 weeks respectively.The control group was given a home rehabilitation exercise manual,while the intervention group developed mHealth-based exercise rehabilitation based on this exercise prescription.The muscle strength and quality of life levels of the two groups were compared after the intervention.Result:Patients with mHealth-based exercise rehabilitation had significantly higher lower limb muscle strength than the control group after 3 weeks of intervention(P<0.05).The fatigue and nausea,and vomiting symp-toms in the quality of life domains were significantly improved compared with the control group(P<0.05).Conclusion:Home-based exercise rehabilitation based on mHealth can effectively improve lower limb muscle strength,fatigue,and nausea and vomiting symptoms in patients discharged from the hospital after surgery for hepatocellular carcinoma.It is an effective way to improve the rehabilitation of patients discharged from the hospital for hepatocellular carcinoma.

Objective:To construct a management program for postoperative home exercise rehabilitation in patients undergoing liver cancer surgery, and to provide guidance for improving home exercise capacity after liver cancer surgery.Methods:A mixed study design was used to summarize the best evidence for a postoperative home exercise rehabilitation program for patients with liver cancer based on a literature review from January to June 2022, and the first draft of a postoperative home exercise rehabilitation program for liver cancer patients was formed after discussion in the research team, and discussed in an expert validation meeting, and the first draft of the program was revised and improved according to the expert′s opinion in combination with clinical practice.Results:This study included 14 articles, including 4 clinical guidelines, 3 systematic evaluations, 2 randomized controlled studies, 3 class experimental research and 2 expert consensuses. And 22 pieces of evidence were included in the summary of evidence, including the principle of exercise, supervision of exercise, type of exercise, time and frequency of exercise, and intensity of exercise. A total of 10 experts participated in the expert validation meeting, with 6 males and 4 females, aged (53.31 ± 10.23) years, with an expert authority coefficient of 0.944, and the final home exercise rehabilitation program for postoperative patients with liver cancer was formed to include six aspects, including pre-exercise assessment, warm-up exercise, whole-body exercise, stretching exercise, organizing exercise, and exercise detection and follow-up.Conclusions:The home exercise rehabilitation program for postoperative liver cancer surgery patients is scientific, practical and feasible, and it is a systematic, standardized and safe exercise management model, which can be used for home guidance of postoperative exercise rehabilitation for liver cancer patients.

Pingyangmycin gelatin microspheres(PYM-GMS) was prepared by optimal double-phase emulsified condensation polymerization for the interventional Chemoembolization with carotid artery therapy, and its release characteristics were studied in vivo and in vitro. The results of three ways of administration(vein drop, artery perfusion and artery embolization) were compared. The experiment indicates that the diameter of PYM-GMS is more appropriate for the application in external carotid artery embolization with PYM-GMS, which significantly reduces the circulating drug level and the dosage, prolongs the time period of higher drug concentration, achieves the purpose of sustained release and targeted tumor therapy.
Animals ; Antineoplastic Agents ; administration & dosage ; pharmacokinetics ; Bleomycin ; administration & dosage ; analogs & derivatives ; pharmacokinetics ; Chemotherapy, Cancer, Regional Perfusion ; Drug Compounding ; methods ; Female ; Gelatin ; In Vitro Techniques ; Infusions, Intravenous ; Male ; Microspheres ; Particle Size ; Rabbits