1.Exploring the etiology,pathogenesis,prevention and treatment of cardiac remodeling in microgravity based on the trinity view of"Physique-Qi-Spirit"
Sitong YAN ; Luyang LIU ; Jiarou WANG ; Kailong ZHOU ; Peng TIAN ; Qian NAN ; Huiyuan SUN
Space Medicine & Medical Engineering 2025;36(5):458-463
Cardiac remodeling in microgravity exerts effects on astronauts'health and space mission efficiency.This paper analyzes the etiology,pathogenesis,prevention,and treatment of cardiac remodeling in microgravity based on the Trinity View of"Physique-Qi-Spirit"of traditional Chinese medicine.The microgravity environment disrupts the heaven-earth qi interaction law described in"Suwen Yin Yang Ying Xiang Da Lun":"Earth qi ascends to form clouds through heavenly evaporation,while heaven qi descends as rain".This disruption causes upward reversal of human qi and cephalad fluid shift,consequently influencing the dynamic balance of the physique-qi-spirit system and inducing cardiac remodeling.The core pathogenesis initiates with qi upward reversal at the initial stage,advances through spiritual disturbance during progression,and culminates in physical impairment at the terminal stage.We therefore propose a holistic"physique-qi-spirit"co-regulation strategy implemented via three therapeutic principles:regulating qi,stabilizing spirit,and restoring physique.This approach aims to restore the dynamic balance of the"physique-qi-spirit"system in microgravity,apply the concept of"preventive treatment of diseases",holistically prevent or delay cardiac remodeling,and provide Traditional Chinese Medicine solutions for safeguarding astronauts'cardiovascular health.
2.Effects of Zhuang Medicine Jib on Spastic Hemiplegia after Stroke
Kailong WANG ; Jun PANG ; Jinming HUANG ; Hongliang TANG ; Longming LEI ; Binbin ZHOU ; Chong ZHANG ; Zhenbao GAN
Chinese Journal of Rehabilitation Theory and Practice 2017;23(1):89-91
Objective To observe the effect of Zhuang Medicine Jib on spasm in hemiplegics after stroke. Methods From January, 2014 to December, 2015, 55 patients with spastic hemiplegia after stroke were divided randomly into treatment group (n=27) and control group (n=28). Both groups accepted routine rehabilitation and acupuncture, while the treatment group accepted Zhuang Medicine Jib in addition. They were assessed with modified Ashworth Scale (MAS), Barthel index (BI), Simpling Fugl-Meyer Assessment (FMA) before and four weeks after treatment. The side-effects within three months after treatment were recorded. Results The scores of MAS, BI and FMA improved in both groups after treatment (t>3.32, P<0.01), and improved more in the treatment group than in the control group (t>2.286, P<0.05). No side-effect was found in the follow-up. Conclusion Zhuang Medicine Jib can further relieve spasm after stroke, and improve the motor function and activities of daily living.
3.Ensemble Partial Least Squares Algorithm Based on Variable Clustering for Quantitative Infrared Spectrometric Analysis
Yiming BI ; Guohai CHU ; Jizhong WU ; Kailong YUAN ; Jian WU ; Fu LIAO ; Jun XIA ; Guangxin ZHANG ; Guojun ZHOU
Chinese Journal of Analytical Chemistry 2015;(7):1086-1091
Due to the ability of overcoming both the dimensionality and the collinear problems of the spectral data, partial least squares ( PLS ) is in ever increasingly used for quantitative spectrometric analysis, especially for near-infrared spectrum, mid-infrared spectrum and Raman spectrum. In this work, an improved PLS algorithm is proposed for efficient information extraction and noise reduction. The spectral variables are clustering to several subsets, and several sub-models are built for each subset. Then, the sub-models are re-weighted and ensemble to the final model. Experiments on two near-infrared datasets ( octane number prediction in gasoline and nicotine prediction in tobacco leafs ) demonstrate that the new method provides superior prediction performance and outperformed the conventional PLS algorithm, and the root mean square error of prediction ( RMSEP) is reduced by 32% and 22%, respectively.
4.Effect of Massage at Head-neck Acupoints on Dysphagia post Stroke
Kailong WANG ; Yong HUANG ; Binbin ZHOU ; Dongyu WU
Chinese Journal of Rehabilitation Theory and Practice 2014;(3):269-271
Objective To observe the effect of massage at acupoints on head, neck and face on dysphagia after stroke. Methods 60 stroke patients with dysphagia were randomly divided into treatment group (n=30) and control group (n=30). The control group received conventional rehabilitation, including acupuncture and swallowing training, and the treatment group received acupoint massage on head,neck and face in addition. They were assessed with Standardized Swallowing Assessment (SSA) before and 4 weeks after treatment. Results The score of SSA improved in both groups (P<0.001), and improved more in the treatment group than in the control group (P<0.001) after treatment. Conclusion Conventional rehabilitation with acupoint massage is more effective on dysphagia after stroke.


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