Peripheral neuropathic pain(PNP)is a chronic pain condition caused by the primary damage or the dysfunction of the peripheral nervous system.The incidence of PNP is relatively high and increases with age,and PNP has significant impact on patients'quality of life.Common syndromes associated with PNP include postherpetic neuralgia,painful diabetic peripheral neuropathy,trigeminal neuralgia,and painful radiculopathy.Buyang Huanwu Decoction,originating from Wang Qingren's Yi Lin Gai Cuo(Corrections on the Errors of Medical Works during)the Qing Dynasty and mainly having the actions of replenishing qi and promoting blood circulation,removing stasis and unblocking collaterals,is primarily known as a representative formula for treating stroke due to qi deficiency and blood stasis.Nowadays,modern practitioners have extended its application in treating various multi-system diseases in internal medicine.This paper systematically reviewed clinical studies and pharmacological mechanisms of Buyang Huanwu Decoction in treating PNP over the past 20 years.The results indicated that the combination of herbs in Buyang Huanwu Decoction has multi-component,multi-target,and multi-pathway effects on repairing nerve damage,nourishing nerves,promoting nerve regeneration,and alleviating neuropathic pain.Buyang Huanwu Decoction shows significant efficacy in treating PNP syndromes caused by neuropathic damage resulting from various etiological factors.This article reviewed both clinical observation and basic research on Buyang Huanwu Decoction in treating PNP,aiming to provide references for the clinical treatment of PNP and to expand the clinical applications of Buyang Huanwu Decoction.

Objective To explore the effect of transcranial direct current stimulation(tDCS)on re-sponse inhibition using behavioral and electroencephalographic(EEG)measures.Methods Twenty-eight healthy university students majoring in physical education were recruited and randomly assigned to ei-ther a verum tDCS group or a sham tDCS group.The study employed a Go/No-go task paradigm,with tDCS serving as the intervention.Event-related potentials(ERPs)were utilized to compare and analyze the changes in response inhibition performance between the two groups before and after the in-tervention.Results 1)After tDCS intervention,Go reaction time of the verum tDCS group was signifi-cantly shorter compared to baseline(P<0.05),while no significant differences were found in Go accu-racy or No-go accuracy.However,no significant changes were found in the above measurements of the sham group.2)As to EEG,during the Go task,the verum tDCS group exhibited significantly larger P3 amplitudes and significantly shorter P3 latencies over the central-parietal region after interven-tion(P<0.05),while the sham group showed no significant differences.In the No-go task,the former group showed significantly shorter P3 latencies after intervention(P<0.05),with no significant changes observed in the sham group.Inter-group comparisons revealed no significant differences in any base-line measures.However,after the intervention,the verum tDCS group demonstrated significantly short-er P3 latencies in the Go task than the sham group(P<0.05),with no significant differences in P3 amplitude during the Go task,or in P3 amplitude and latencies during the No-go task.Conclusion The tDCS intervention leads to faster response speed,enhances inhibitory control,improves processing efficiency,and recruits more attentional resources,indicating a moderate improvement in response inhi-bition performance.

Objective To explore the effect of transcranial direct current stimulation(tDCS)on re-sponse inhibition using behavioral and electroencephalographic(EEG)measures.Methods Twenty-eight healthy university students majoring in physical education were recruited and randomly assigned to ei-ther a verum tDCS group or a sham tDCS group.The study employed a Go/No-go task paradigm,with tDCS serving as the intervention.Event-related potentials(ERPs)were utilized to compare and analyze the changes in response inhibition performance between the two groups before and after the in-tervention.Results 1)After tDCS intervention,Go reaction time of the verum tDCS group was signifi-cantly shorter compared to baseline(P<0.05),while no significant differences were found in Go accu-racy or No-go accuracy.However,no significant changes were found in the above measurements of the sham group.2)As to EEG,during the Go task,the verum tDCS group exhibited significantly larger P3 amplitudes and significantly shorter P3 latencies over the central-parietal region after interven-tion(P<0.05),while the sham group showed no significant differences.In the No-go task,the former group showed significantly shorter P3 latencies after intervention(P<0.05),with no significant changes observed in the sham group.Inter-group comparisons revealed no significant differences in any base-line measures.However,after the intervention,the verum tDCS group demonstrated significantly short-er P3 latencies in the Go task than the sham group(P<0.05),with no significant differences in P3 amplitude during the Go task,or in P3 amplitude and latencies during the No-go task.Conclusion The tDCS intervention leads to faster response speed,enhances inhibitory control,improves processing efficiency,and recruits more attentional resources,indicating a moderate improvement in response inhi-bition performance.

Objective: To examine the prevalence and associated factors of seeking casual male sexual partners among men who have sex with men (MSM) students in Guangzhou, and to provide a reference for health education and intervention. Methods: A cross-sectional study was conducted to recruit 189 MSM students aged 18 and 28 via voluntary counseling and testing (VCT) clinics, Lingnan partners and Zhitong charity from May 2017 to April 2018. An anonymous electronic questionnaire was administrated to collect information on sociodemographic and sexual behavior characteristics. Chi-square test and non-conditional Logistic regression analysis were performed to explore the associated factors of casual homosexual behavior among MSM students. Results: In the past 6 months, 63.49% (120/189) of them reported casual male partners, and the rate of consistent condom use was 61.67%(74/120). Multivariate Logistic regression analysis showed that participants who had multiple sex partners in the past 6 months were more likely to seek male casual partners(aOR=9.13, 95%CI=4.27-19.53). Individuals who used recreational drugs before sex were at a higher risk of having casual sex behaviors(aOR=3.06, 95%CI=1.08-8.62). MSM students who had steady homosexual partners had a lower risk to seek casual sex(aOR=0.43, 95%CI=0.19-0.98). Conclusion The proportion of seeking casual male sexual partners among MSM students in Guangzhou was relatively high. The publicity and education should be strengthened among those who had multiple sex partners, with no steady homosexual partners and used recreational drugs before sex, to reduce the casual sex behaviors.