Objective To explore the potential categories of psychosocial adaptation in psoriasis patients and their differences in social alienation.Methods Using a cross-sectional survey design,convenience sam-pling was used to select 376 psoriasis patients from multiple hospitals in Shandong Province from September to December 2022.Participants completed the general information questionnaire,Psychosocial Adaptation to Illness Scale(PAIS-SR),Acceptance and Action Questionnaire-Ⅱ(AAQ-2),and General Alienation Scale(GAS).Latent profile analysis was performed using Mplus8.0 software to identify psychosocial adaptation patterns of psoriasis patients,and SPSS25.0 was used to compare social alienation differences among different adaptation groups.Results Psoriasis patients could be divided into two latent profiles:moderate psychosocial adaptation group(31.38％)and low psychosocial adaptation group(68.62％).Medical payment method,dis-ease recurrence,psoriasis subtype,disease duration,family history,skin lesion exposure,and AAQ-2 scores were identified as main influencing factors(P＜0.05).Significant differences in total GAS scores were found between the two groups(P＜0.05).Conclusion The psychosocial adaptation of psoriasis patients shows het-erogeneity and could be classified into two latent profiles.Targeted interventions should be implemented to improve psychosocial adaptation levels.

Objective By means of telephone follow-up care intervention, we aimed to explore the effect of clinical efficacy and the ability to cope with adverse reaction among uterine adenomyoma postoperative patients after receiving GnRH-a treatment.Methods From January 2009 to December 2011, 115 patients who underwent uterine adenomyoma surgery combined with GnRH-a treatment were divided into two groups.The research group of 55 patients received positive guidance of food, rest, activities, life, spirit and so on through telephone, also a continuous psychological intervention of subsequent visit reminding and the solutions to adverse reactions.Then the 60 cases in the control group only received the conventional outpatient follow-up at regular intervals according to their competent doctor, without any telephone follow-up of nursing intervention.Results In the research group, the dysmenorrhea of 53 patients ( 96.36%) was relieved or disappeared, 52 patients (94.54%) did not relapse after surgery.The menstrual blood volume was decreased and the period of the menstrual was reduced within 52 patients (94.54%).Those values of the control group were 49(89.09%), 51(92.72%) and 50(90.90%).There was no significant difference between groups (χ2 =1.21, 0.00, 0.13, respectively;P >0.05).After the treatment of GnRH-a, the adverse reactions such as hot flashes, night sweats, skin rash as well as acne, and the compliance were significantly improved (χ2 =6.15, 6.15, 4.45, 5.04, 4.25, 4.25, respectively; P<0.05).There were also significant differences in keeping medication, regular examine, changing bad habits and the compliance of coping with the adverse reaction (χ2 =5.49, 7.31, 14.31, 10.45, respectively;P<0.05).Conclusions Telephone follow-up care intervention can improve the compliance of uterine adenomyoma postoperative patients receiving GnRH-a treatment, reduce the adverse reaction and help patients cope with adverse reactions effectively in the right way, and lead to better relationship between nurses and patients.