Objective To study the application value of endoscopic purse-string sutures with titanium clips and endoloops for the gastric wall defect during endoscopic full-thickness resection (EFTR). Methods Data of iffteen hospitalized patients with gastric submucosal tumor (SMT) undergone EFTR was reviewed. The patients were all applied with endoscopic purse-string sutures with titanium clips and endoloops, which was performed after the EFTR when the gastric walls were perforated artiifcially. Results The gastric tumors were complete successfully resected in the iffteen patients through endoscopic surgery, applied the purse-string sutures with titanium clips and endoloops after the EFTR when the gastric walls were perforated artiifcially. Approximately, ifve clips were utilized on average. Postoperative surgical wound healing was followed up for 6 months, no tumors recurred. Conclusion It is safe, minimally invasive treatment method for rapid rehabilitation in endoscopic full-thickness resection utilized purse-string sutures with titanium clips and endoloops.

A 70-year-old female patient with motor neuron disease was given an IV infusion of ciprofloxacin 0.4 g once daily because of acute exacerbation of chronic bronchitis. On day 10,she developed hypokalemia(blood potassium 2.7 mmol/L)and potassium supplement was given. On day 11,the patient experienced loss of consciousness and cardiac arrest. The patient was given chest compression instantly and regained consciousness in three minutes. Electrocardiogram showed torsades de pointes ventricular tachycardia. Her QT corrected by heart rate(QTc)was 546 ms and blood potassium was 3.4 mmol/L.Potassium supplement was given again. On day 13,the patient′s QTc was 561 ms and blood potassium was 3.2 mmol/L. Ciprofloxacin induced QT interval prolongation was considered. On day 6 of ciprofloxacin withdrawal,the patient′s QTc was 460 ms and blood potassium was 3.9 mmol/L.

A 70-year-old female patient with motor neuron disease was given an IV infusion of ciprofloxacin 0.4 g once daily because of acute exacerbation of chronic bronchitis. On day 10,she developed hypokalemia(blood potassium 2.7 mmol/L)and potassium supplement was given. On day 11,the patient experienced loss of consciousness and cardiac arrest. The patient was given chest compression instantly and regained consciousness in three minutes. Electrocardiogram showed torsades de pointes ventricular tachycardia. Her QT corrected by heart rate(QTc)was 546 ms and blood potassium was 3.4 mmol/L.Potassium supplement was given again. On day 13,the patient′s QTc was 561 ms and blood potassium was 3.2 mmol/L. Ciprofloxacin induced QT interval prolongation was considered. On day 6 of ciprofloxacin withdrawal,the patient′s QTc was 460 ms and blood potassium was 3.9 mmol/L.