1.Quality of life in lymphoma patients treated by different regimens under unaccompanied nursing care mode
Xiao ZHANG ; Rui ZOU ; Shenyan GU ; Nana PING ; Qian ZHU ; Junhong LI ; Zhengming JIN ; Changju QU
Journal of Leukemia & Lymphoma 2024;33(12):734-739
Objective:To investigate the quality of life of lymphoma patients receiving different treatment methods under unaccompanied nursing care mode.Methods:A cross sectional study was conducted. A total of 374 lymphoma patients who received chemotherapy, hematopoietic stem cell transplantation, chimeric antigen receptor T (CAR-T) cell therapy, or other targeted immunotherapy under unaccompanied nursing care mode in the First Affiliated Hospital of Soochow University from January 2023 to December 2023 were selected. The basic information of patients was collected through a questionnaire, and the Cancer Rehabilitation Evaluation System-Short Form (CARES-SF) was used to score the quality of life of patients from physiological, psychosocial, the relationship with healthcare professionals, marital relations, sexual function, and the overall health aspects. The higher score indicated the worse quality of life. The differences in quality of life among patients stratified by the different treatment methods and high-intensity treatment (CAR-T cell therapy or transplantation) and low-intensity treatment (other treatment methods) under unaccompanied care mode were compared.Results:Among the 374 patients, 62 received autologous hematopoietic stem cell transplantation, 13 received allogeneic hematopoietic stem cell transplantation, and 36 received CAR-T cell therapy. There were no statistically significant differences in the dimensions of CARES-SF and the overall health aspects scores between the transplantation treatment group and the non-transplantation treatment group (all P > 0.05). For non-transplant patients, there were no statistically significant differences in the dimensions of CARES-SF and overall health aspects scores between the CAR-T cell treatment group and the non-CAR-T cell treatment group (all P > 0.05); for transplant patients, the physiological dimension score [ M ( IQR)] of CARES-SF in the allogeneic hematopoietic stem cell transplantation group was higher than that in the autologous hematopoietic stem cell transplantation group [16 points (9 points) vs. 8 points (9 points)], and the difference was statistically significant ( Z = -2.30, P = 0.021), but there were no statistically significant differences in the scores of other dimensions and overall health aspects (all P > 0.05). There were no statistically significant differences in the dimensions of CARES-SF and overall health aspects scores in the high-intensity treatment group and the low-intensity treatment group (all P > 0.05). Conclusions:There is no significant difference in the quality of life of lymphoma patients receiving different treatment methods under the unaccompanied care mode, while lymphoma patients receiving high-intensity treatment and low-intensity treatment have similar life quality. Lymphoma patients receiving high-intensity treatment may benefit more from the unaccompanied care mode.
2.Development of Pressure Injury Prevention Behavior Assessment Scale (Patient Version) and its reliability and validity test
Rong HU ; Ning NING ; Jiali CHEN ; Lei LEI ; Zhongmin FU ; Peifang LI ; Junhong QU
Chinese Journal of Modern Nursing 2023;29(17):2300-2304
Objective:To compile Pressure Injury Prevention Behavior Assessment Scale (Patient Version) and conduct reliability and validity test.Methods:Guided by the theory of "patient participation in patient safety" , an item pool was initially constructed through literature review and patient interview, and Delphi expert consultation method was used to evaluate and screen items. From October to November 2021, the convenient sampling method was adopted to select 160 inpatients of Orthopedics Department of West China Hospital of Sichuan University as research objects for questionnaire survey, project analysis, reliability and validity test.Results:The formed Pressure Injury Prevention Behavior Assessment Scale (Patient Version) contained 21 items in 3 dimensions. The Cronbach 's α coefficient was 0.947, and the broken half reliability coefficient was 0.873. The content validity index at scale level was 0.958, and the content validity index at item level was 0.909-1.000. Exploratory factor analysis showed that the cumulative variance contribution rate of the three common factors was 61.931%. Conclusions:It is preliminarily verified that Pressure Injury Prevention Behavior Assessment Scale (Patient Version) has good reliability and validity, which can be used to evaluate the current situation of orthopaedic patients participating in the prevention of stress injury behavior and provide a basis for the corresponding intervention measures.
3.Investigation on the current situation and influencing factors of mood disorders in patients with thoracic and lumbar osteoporotic fractures
Lei LEI ; Ning NING ; Jiali CHEN ; Peifang LI ; Mei YAO ; Ye LI ; Liqun WANG ; Lingli LI ; Junhong QU
Chinese Journal of Practical Nursing 2022;38(22):1690-1695
Objective:To understand the current situation of mood disorders in patients with thoracic and lumbar osteoporotic fractures and to preliminarily explore its influencing factors.Methods:A cross-sectional survey method was used to select 212 patients with thoracic and lumbar osteoporotic fractures from Department of Orthopedics, West China Hospital, Sichuan University, from January 2018 to September 2020 as the research subjects. The general information questionnaire, Huaxi Emotional-distress Index, Pittsburgh Sleep Quality Index (PSQI) and pain Visual Analogue Scale (VAS) were used to investigate them.Results:The incidence of mood disorders in patients with thoracic and lumbar osteoporotic fractures was 10.38% (22/212). The results of multivariate regression analysis showed that age, days of injury, PSQI score and pain VAS score were the influencing factors of emotional disturbance in patients with thoracic and lumbar osteoporotic fractures ( t values were -3.72-7.66, all P<0.05). Conclusions:Patients with thoracic and lumbar osteoporotic fractures have mood disorders. Age, injury days, PSQI score and VAS score are related to the occurrence of mood disorders in patients with thoracic and lumbar osteoporotic fractures. More attention should be payed to the influencing factors of mood disorders in patients,and timely measures should be taken for individualized intervention.
4.Application effectiveness of fast track surgery concept in terrible triad of the elbow
Xiaoyan LIU ; Lin ZHANG ; Junhong QU ; Yi LUO ; Xiaoling HOU
Chinese Journal of Modern Nursing 2017;23(32):4122-4125
Objective To explore the application effect of fast track surgery concept in terrible triad of the elbow to improve the nursing quality and promote the rehabilitation of patients.Methods Patients with terrible triad of the elbow in Orthopedics Department were selected using convenient sampling method. The control group included 26 cases who adopted traditional recovery treatment in 2014;the experimental group contained 30 cases who received fast track surgery in 2015. The Mayo elbow-performance score and patients′ satisfaction were compared between two groups.Results After the implementation of fast track surgery mode,the Mayo elbow-performance score was (86.15±8.16) in the experimental group and (72.67±12.51) in the control group;the difference was statistically significant (t=4.697,P<0.01). The patients′ satisfaction was 96.7% in the experimental group and 92.3% in the control group,with statistically significant difference between two groups (χ2=6.897,P<0.01).Conclusions Fast track surgery concept,which can help the function recovery of patients with terrible triad of the elbow and improve patients′ satisfaction,is an important innovation and perfection of traditional recovery concept.

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