Background: Nipple eczema (NE) manifests as pruritic or painful erythema, often accompanied by oozing, erosion, and lichenification. NE is observed in 6%–23% of patients with atopic dermatitis (AD); its prevalence is higher among adolescent and young adult women. Objective: To determine the prevalence and clinical correlates of NE in patients with AD. Methods: We conducted a retrospective cross-sectional study from July to December 2023, enrolling patients diagnosed with AD. Participants completed a questionnaire regarding their symptoms of AD and NE, as well as the impact of NE on their daily lives. Results: Of the 200 patients, 55 (27.5%) reported of having experienced NE. The mean age at NE onset was 22.75±9.77 years. The proportion of females with NE (70.9%) was significantly higher relative to those without NE (38.6%) (p<0.001). Factors significantly associated with the presence of NE in AD patients included female sex (odds ratio [OR], 4.90; 95% confidence interval [CI], 1.99–12.07; p=0.001), increased AD itch numerical rating scale (NRS) score (OR, 1.46; 95% CI, 1.11–1.91; p=0.007), increased AD pain NRS score (OR, 1.20; 95% CI, 1.01–1.44; p=0.041) and higher Investigator Global Assessment score (OR, 5.38; 95% CI, 2.07–13.99; p=0.001). Regarding nipple-specific health-related quality of life (HRQoL), 35.8% of patients reported severe impairment in HRQoL due to NE, and 45.3% experienced severe emotional distress. Conclusion Although the area affected by NE is small, dermatologists should be aware of its association with severe AD characteristics, and its significant impact on patient HRQoL.

Eczema herpeticum is a widespread herpes simplex infection that favors eczema-damaged skin, including skin involved with atopic dermatitis. Here we report a case of a 27-year-old woman who presented with febrile, painful, punched-out, erosive, macular eruptions and crusts on her face, upper trunk, and antecubital fossae. Polymerase chain reaction analyses of the blood and skin lesions were positive for type 1 herpes simplex virus, and blood cultures established on admission showed methicillin-sensitive Staphylococcus aureus. She was diagnosed with bacteremia superimposed on eczema herpeticum. True bacteremia rather than contaminated blood cultures was suspected because her fever did not improve after 2 days despite the administration of antivirals. Repeated scratches to the lesional skin most likely aggravated the epidermal barrier damage, enabling the penetration of the dermal vessels by colonized S. aureus.

Background: Scabies is a parasitic infection caused by the Sarcoptes scabiei var. hominis mite. Its incidence has been increasing in recent years; however, no study has evaluated the clinical aspects of scabies in children and adolescents in Korea. Objective: To evaluate the clinical characteristics and epidemiological features of scabies among children and adolescents and to investigate the clinical efficacy of topical therapies for the treatment of scabies. Methods: We retrospectively reviewed the medical records of 62 patients under 18 years of age with scabies during a 10-year-period. Results: Sixty-two patients with 62 scabies were investigated. These patients showed scabies mites or eggs under microscopic examination or showed clinical improvement after treatment. There were 36 boys (58.1%) and 26 girls (41.9%). The mean age of the boys was 9.3 years and that of the girls was 8.2 years. The most common primary lesions were erythematous papules (93.5%), and the commonest sites of the skin lesions were the hand (64.5%) and the trunk (61.3%). The most common suspected mode of transmission was through contact among families living together. The mean time to complete treatment was 46.1 days using 1% gamma benzene hexachloride lotion, 37.1 days using 10% crotamiton ointment, and 22.8 days using 5% permethrin cream. Conclusion We confirmed the epidemiological features and clinical characteristics of scabies in children and adolescents, including contact sources and treatment. This study could provide useful data for the prevention and management of scabies in children and adolescents.

Eczema herpeticum is a widespread herpes simplex infection that favors eczema-damaged skin, including skin involved with atopic dermatitis. Here we report a case of a 27-year-old woman who presented with febrile, painful, punched-out, erosive, macular eruptions and crusts on her face, upper trunk, and antecubital fossae. Polymerase chain reaction analyses of the blood and skin lesions were positive for type 1 herpes simplex virus, and blood cultures established on admission showed methicillin-sensitive Staphylococcus aureus. She was diagnosed with bacteremia superimposed on eczema herpeticum. True bacteremia rather than contaminated blood cultures was suspected because her fever did not improve after 2 days despite the administration of antivirals. Repeated scratches to the lesional skin most likely aggravated the epidermal barrier damage, enabling the penetration of the dermal vessels by colonized S. aureus.