1.Impact of Korean Military Service on the Prevalence of Steatotic Liver Disease: A Longitudinal Study of Pre-enlistment and InService Health Check-Ups
Jaejun LEE ; Jae Hyeop JUNG ; Sung Jun CHOI ; Beomman HA ; Hyun YANG ; Pil Soo SUNG ; Si Hyun BAE ; Jeong-A YU
Gut and Liver 2024;18(5):888-896
Background/Aims:
Young Korean men are obligated to serve in the military for 18 to 21 months. We investigated the effects of military service on steatotic liver disease (SLD) and other metabolic parameters.
Methods:
Pre-enlistment health check-up performed from 2019 to 2022 and in-service health check-up performed from 2020 to 2022 were merged as paired data. SLD was defined as a hepatic steatosis index of 36 or higher. Hypertension (HTN) and hypertriglyceridemia were also included in the analysis.
Results:
A total of 503,136 paired cases were included in the analysis. Comparing pre-enlistment and in-service health check-ups, the prevalence of SLD (22.2% vs 17.6%, p<0.001), HTN (7.6% vs 4.3%, p<0.001), and hypertriglyceridemia (8.1% vs 2.9%, p<0.001) decreased during military service. In terms of body mass index, the proportion of underweight (8.2% vs 1.4%, p<0.001) and severely obese (6.1% vs 4.9%, p<0.001) individuals decreased over time. Regarding fac-tors associated with SLD development and resolution, age was positively associated with SLD development (odds ratio, 1.146; p<0.001) and a health check-up interval of <450 days was a protective factor for SLD development (odds ratio, 0.746; p<0.001). Those serving in the marines were less likely to develop SLD, whereas those serving in the navy were more likely to develop SLD. Serving in the army or the navy was negatively associated with SLD resolution, whereas serving in the air force was positively associated with SLD resolution.
Conclusions
The prevalence of SLD, HTN, and hypertriglyceridemia decreased substantially during Korean military service.
2.Analysis of the cardiopulmonary resuscitation-related complications based on computed tomography
Journal of the Korean Society of Emergency Medicine 2020;31(5):431-439
Objective:
High-quality cardiopulmonary resuscitation (CPR) needs to be provided to cardiac arrest victims. The chest compression at a 5-6 cm depth and 100-120 beats per minute are recommended according to the 2015 CPR guidelines. The physical forces to the patient’s chest wall cause inevitable complications. This study analyzed the CPR-related complications based on computed tomography (CT).
Methods:
This was a retrospective, single-center study. The study period was from 2009 to 2019. The cardiac arrest victims received the CPR in or out-of-hospital. After the return of spontaneous circulation, CTs were performed on some survivors. The complications detected on CTs were reviewed, and the types and frequencies of complications, age, sex, arrest location, CPR duration, the survival discharge were investigated.
Results:
Among 1,357 cardiac arrest patients during the study period, 368 patients were enrolled. The average age was 64.2, and 66.3% were male. The average CPR duration was 24.6 minutes. The most frequent complication was rib fracture (73.6%). Lung contusion (41.3%), hemothorax (22.0%), sternal fracture (19.3%), and retrosternal hemorrhage (13.6%) were also detected. Those with rib fractures, sternal fractures, and retrosternal hemorrhage were older (P<0.001). Those with rib fractures, lung contusion, hemothorax received longer CPR (P=0.032, P=0.003, and P=0.041). Low survival discharge rates were observed in patients with rib fractures, sternal fractures, and pneumothorax (P=0.002, P=0.014, and P=0.016).
Conclusion
The rib fracture, sternal fracture, and retrosternal hemorrhage were frequent in older patients. Those with rib fractures, lung contusion, or hemothorax received the longer CPR. The survival discharge rates were low in the rib fracture, sternal fracture, pneumothorax patients.
3.Analysis of the cardiopulmonary resuscitation-related complications based on computed tomography
Journal of the Korean Society of Emergency Medicine 2020;31(5):431-439
Objective:
High-quality cardiopulmonary resuscitation (CPR) needs to be provided to cardiac arrest victims. The chest compression at a 5-6 cm depth and 100-120 beats per minute are recommended according to the 2015 CPR guidelines. The physical forces to the patient’s chest wall cause inevitable complications. This study analyzed the CPR-related complications based on computed tomography (CT).
Methods:
This was a retrospective, single-center study. The study period was from 2009 to 2019. The cardiac arrest victims received the CPR in or out-of-hospital. After the return of spontaneous circulation, CTs were performed on some survivors. The complications detected on CTs were reviewed, and the types and frequencies of complications, age, sex, arrest location, CPR duration, the survival discharge were investigated.
Results:
Among 1,357 cardiac arrest patients during the study period, 368 patients were enrolled. The average age was 64.2, and 66.3% were male. The average CPR duration was 24.6 minutes. The most frequent complication was rib fracture (73.6%). Lung contusion (41.3%), hemothorax (22.0%), sternal fracture (19.3%), and retrosternal hemorrhage (13.6%) were also detected. Those with rib fractures, sternal fractures, and retrosternal hemorrhage were older (P<0.001). Those with rib fractures, lung contusion, hemothorax received longer CPR (P=0.032, P=0.003, and P=0.041). Low survival discharge rates were observed in patients with rib fractures, sternal fractures, and pneumothorax (P=0.002, P=0.014, and P=0.016).
Conclusion
The rib fracture, sternal fracture, and retrosternal hemorrhage were frequent in older patients. Those with rib fractures, lung contusion, or hemothorax received the longer CPR. The survival discharge rates were low in the rib fracture, sternal fracture, pneumothorax patients.
4.The Incidence and Predictors of Postoperative Atrial Fibrillation After Noncardiothoracic Surgery.
Gwan Hyeop SOHN ; Dae Hee SHIN ; Kyung Min BYUN ; Hye Jin HAN ; Soo Jin CHO ; Young Bin SONG ; Jun Hyung KIM ; Young Keun ON ; June Soo KIM
Korean Circulation Journal 2009;39(3):100-104
BACKGROUND AND OBJECTIVES: The incidence of postoperative atrial fibrillation after noncardiothoracic surgery is known to be very rare; there have been few prior studies on this topic. We evaluated the incidence, predictors, and prognosis of atrial fibrillation after noncardiothoracic surgery. SUBJECTS AND METHODS: Patients who underwent noncardiothoracic surgery at our medical center under general anesthesia were enrolled. We reviewed medical records retrospectively and evaluated whether the atrial fibrillation developed postoperatively or was pre-existing. Patients who had a previous history of atrial fibrillation or atrial fibrillation on the pre-operative electrocardiogram were excluded. RESULTS: Between January 2005 and December 2006, 7,756 patients (mean age: 69 years, male: 46%) underwent noncardiothoracic surgery in Samsung Medical Center and 30 patients (0.39%) were diagnosed with newly-developed atrial fibrillation. Patients who developed atrial fibrillation were significantly older and had significantly lower body mass indexes. Newly-developed atrial fibrillation was detected in 0.53% of the male patients and 0.26% of the female patients. The incidence of postoperative atrial fibrillation after an emergency operation was more frequent than that of elective operations (p<0.001). According to the multivariate analysis, age and emergency operations were independent predictors for new onset atrial fibrillation after noncardiothoracic surgery. Postoperative atrial fibrillation developed after a median of 2 days after the noncardiothoracic surgery and was associated with a longer hospitalization and increased in-hospital mortality. Four (13.3%) patients died and the causes of death were non-cardiovascular events such as pneumonia or hemorrhage. CONCLUSION: Postoperative atrial fibrillation after noncardiothoracic surgery is a rare complication and is associated with older age and emergency operations. Patients who develop atrial fibrillation have longer hospitalizations and higher in-hospital mortality rates.
Anesthesia, General
;
Atrial Fibrillation
;
Body Mass Index
;
Cause of Death
;
Electrocardiography
;
Emergencies
;
Female
;
Hemorrhage
;
Hospital Mortality
;
Hospitalization
;
Humans
;
Incidence
;
Male
;
Medical Records
;
Multivariate Analysis
;
Pneumonia
;
Postoperative Complications
;
Prognosis
;
Retrospective Studies
5.Degeneration of Acetabular Articular Cartilage to Bipolar Hemiarthroplasty.
Kyoung Ho MOON ; Jun Soon KANG ; Tong Joo LEE ; Sang Hyeop LEE ; Sung Wook CHOI ; Man Hee WON
Yonsei Medical Journal 2008;49(5):719-724
PURPOSE: This study examined the rate of degeneration of acetabular cartilage by the bipolar head according to time, and also which clinical factors are related to the degeneration of acetabular cartilage. MATERIALS AND METHODS: Among 192 patients (226 hip joints) who received bipolar hemiarthroplasty from August 1996 to August 2002, 61 patients (65 hip joints) were enrolled in this study, who were followed up for more than 2 years and showed no signs of dislocation, infection, or functional problems. A modified form of a computer assisted vector wear analysis program was used to measure the rate of degeneration of the acetabular cartilage. The factors that appeared to affect the rate of acetabular degeneration in the two groups was evaluated. RESULTS: The average linear degenerative change in the acetabular cartilage and the volumetric degenerative change were 0.23 +/- 0.107mm/year and 114 +/- 47.2mm3/year, respectively. The result showed significant differences in activity and HHS between the 2 groups. The HHS showed a reverse relationship with the linear degeneration and volumetric degeneration, and the activity showed a correlation with the linear and volumetric degeneration. CONCLUSION: The acetabular cartilage degenerates faster as the patient' activity increases, and slower with a higher HHS. When surgeons perform hip joint arthroplasty, it is strongly recommended that the life expectancy and the level of activity should be considered when deciding between a hemiarthroplasty and total hip arthroplasty.
Aged
;
Arthroplasty, Replacement, Hip/*adverse effects
;
Cartilage, Articular/*radiography
;
Follow-Up Studies
;
Humans
;
Middle Aged
;
Treatment Outcome
6.A Case of Thyroid MALT Lymphoma without Autoimmune Thyroiditis.
Ok Nyu KONG ; Sang Hyen JOO ; Sun Hye SHIN ; Min Ah NA ; Jun Hyeop AN ; Yang Ho KANG ; Do Youn PARK ; Seok Man SON ; In Ju KIM ; Yong Ki KIM
Journal of Korean Society of Endocrinology 2005;20(3):268-272
A primary thyroid lymphoma is rare among all types of thyroid malignancy. Usually, a thyroid lymphoma is associated with underlying chronic autoimmune thyroiditis. Recently, we experienced a primary thyroid mucosa-associated lymphoid tissue(MALT) lymphoma, with an incidental micropapillary thyroid carcinoma, but lacking evidence of autoimmune thyroiditis. A female patient visited our hospital for further evaluation of a rapidly enlarging, painless thyroid mass which had been stable for 8 years. Lymphocytic thyroiditis or a lymphoma was suspected from fine needle aspiration performed at another hospital. The thyroid function test and other routine laboratory tests were normal. The histopathological findings after a total thyroidectomy revealed a MALT lymphoma with a micropapillary thyroid carcinoma. There was no evidence of chronic autoimmune thyroiditis. This is, to the best of our knowledge, the first case report of a MALT lymphoma arising from the thyroid gland without evidence of chronic autoimmune thyroiditis in Korea
Biopsy, Fine-Needle
;
Female
;
Humans
;
Korea
;
Lymphoma
;
Lymphoma, B-Cell, Marginal Zone*
;
Thyroid Function Tests
;
Thyroid Gland*
;
Thyroid Neoplasms
;
Thyroidectomy
;
Thyroiditis, Autoimmune*
7.A Case of Thyroid MALT Lymphoma without Autoimmune Thyroiditis.
Ok Nyu KONG ; Sang Hyen JOO ; Sun Hye SHIN ; Min Ah NA ; Jun Hyeop AN ; Yang Ho KANG ; Do Youn PARK ; Seok Man SON ; In Ju KIM ; Yong Ki KIM
Journal of Korean Society of Endocrinology 2005;20(3):268-272
A primary thyroid lymphoma is rare among all types of thyroid malignancy. Usually, a thyroid lymphoma is associated with underlying chronic autoimmune thyroiditis. Recently, we experienced a primary thyroid mucosa-associated lymphoid tissue(MALT) lymphoma, with an incidental micropapillary thyroid carcinoma, but lacking evidence of autoimmune thyroiditis. A female patient visited our hospital for further evaluation of a rapidly enlarging, painless thyroid mass which had been stable for 8 years. Lymphocytic thyroiditis or a lymphoma was suspected from fine needle aspiration performed at another hospital. The thyroid function test and other routine laboratory tests were normal. The histopathological findings after a total thyroidectomy revealed a MALT lymphoma with a micropapillary thyroid carcinoma. There was no evidence of chronic autoimmune thyroiditis. This is, to the best of our knowledge, the first case report of a MALT lymphoma arising from the thyroid gland without evidence of chronic autoimmune thyroiditis in Korea
Biopsy, Fine-Needle
;
Female
;
Humans
;
Korea
;
Lymphoma
;
Lymphoma, B-Cell, Marginal Zone*
;
Thyroid Function Tests
;
Thyroid Gland*
;
Thyroid Neoplasms
;
Thyroidectomy
;
Thyroiditis, Autoimmune*
8.A Case of Ectopic ACTH Syndrome Associated with Bronchial Carcinoid.
Young Jin CHOI ; Sang hyen JOO ; Sun Hye SHIN ; Ok Nyu KONG ; Jun Hyeop AN ; Young Dae KIM ; Seok Man SON ; In Joo KIM ; Yong Ki KIM
Journal of Korean Society of Endocrinology 2004;19(1):76-81
Fifteen percent of patients with Cushing's syndrome could be accompanied with nonpituitary tumors that secrets ACTH-the ectopic ACTH syndrome. Among them, bronchial carcinoid is one of the rare causes of the ectopic ACTH syndrome. We experienced a 60-year-old woman who showed conditions of weight gain, generalized edema, hypokalemia, diabetes mellitus, and right middle lung mass. Histologically, the tumor was diagnosed with bronchial carcinoid and was confirmed as an ectopic ACTH syndrome through immunohistochemical staining of ACTH. After resection of the lung mass, blood sugar, electrolytes, generalized weakness, and blood pressure improved.
ACTH Syndrome, Ectopic*
;
Adrenocorticotropic Hormone
;
Blood Glucose
;
Blood Pressure
;
Carcinoid Tumor*
;
Cushing Syndrome
;
Diabetes Mellitus
;
Edema
;
Electrolytes
;
Female
;
Humans
;
Hypokalemia
;
Lung
;
Middle Aged
;
Weight Gain
9.A Case of Pheochromocytoma with Ganglioneuronal Differentiation Producing Vasoactive Intestinal Peptide.
Min Ah NA ; Sang Soo KIM ; Dong Uk KIM ; Jae Hoon CHOI ; Tae Kun LEE ; Ok Nyu KONG ; Jun Hyeop AN ; Jee Yeon KIM ; Han Dong SUNG ; Chul Ho JOUNG ; Seok Man SON ; In Joo KIM ; Yong Ki KIM
Journal of Korean Society of Endocrinology 2003;18(2):227-231
Vasoactive intestinal peptide(VIP) is a 28-amino acid peptide, which may cause secretory diarrhea by stimulating the production of adenylate cyclase. Neuroendocrine tumors, secreting vasoactive intestinal peptide (VIP), are almost always of a pancreatic in origin. However, a pheochromocytoma may produce several neuropeptides, containing VIP, as they are considered to be neuroendocrine tumors. A 57-year-old woman, who presented with chronic watery diarrhea, hypokalemia, weight loss and a left adrenal mass, is described. Histologically, the tumor was diagnosed as a pheoch-romocytoma, with ganglioneuronal differentiation, and was histochemically confirmed to produce a vasoactive intestinal polypeptide. A left adrenal VIP-producing pheochromocytoma was successfully resected. After surgery, her diarrhea subsided and the electrolytes, affected neuroendocrine hormone levels, blood pressure and blood sugar level were normalized.
Adenylyl Cyclases
;
Blood Glucose
;
Blood Pressure
;
Diarrhea
;
Electrolytes
;
Female
;
Humans
;
Hypokalemia
;
Middle Aged
;
Neuroendocrine Tumors
;
Neuropeptides
;
Pheochromocytoma*
;
Vasoactive Intestinal Peptide*
;
Weight Loss
10.A case of thrombotic thrombocytopenic purpura in systemic lupus erythematosus.
Bo Suk KIM ; Jun Hyeop AN ; Woo Hyung BAE ; Sam Suk PARK ; Ho Jin SHIN ; Sung Il KIM ; Im Su KWAK ; Ha Yeon RHA
Korean Journal of Medicine 2001;60(6):593-596
Thrombotic thrombocytopenic purpura (TTP) rarely may be seen in association with autoimmune processes such as scleroderma, rheumatoid arthritis, polyarteritis nodosa, Sj gren's syndrome, and systemic lupus erythematosusus (SLE). The diagnosis of TTP as a syndrome distinct from SLE may be challenging, because both processes may present with some or all elements of the classic pentad considered pathognomonic of the former: microangiopathic hemolytic anemia, fever, thrombocytopenia, neurological deficits, and renal abnormalities. We describe a patient with synchronous TTP and SLE, and review the literature.
Anemia, Hemolytic
;
Arthritis, Rheumatoid
;
Diagnosis
;
Fever
;
Humans
;
Lupus Erythematosus, Systemic*
;
Polyarteritis Nodosa
;
Purpura, Thrombotic Thrombocytopenic*
;
Thrombocytopenia

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