Objective:To explore the effect and application of interventional measures with concept of risk management in adverse events of medical devices,and assess their effectiveness in reducing the incidence of adverse events and in enhancing patients'safety.Methods:The intervention measures with concept of risk management was adopted to carry out risk assessment and hierarchical management for medical devices,and the operating status of medical devices was monitored in real time,and the standard operating procedures of using medical device were formulated for conducting risk management for medical devices.A total of 2,222 conventional medical devices in clinical use at Qingpu Branch of Zhongshan Hospital Affiliated to Fudan University from January 2022 to March 2024 were selected.Among them,1,064 devices(with random values≤0.48)were managed using conventional methods by stratified random sampling without proportional allocation.Another 1,158 devices(random value>0.48)applied the risk intervention management method.A comparative analysis was conducted on the incidence of adverse events of medical devices,the qualified rate of medical device cleaning and the wet package rate of the two management methods,as well as the score of medical device knowledge level of nursing staff.Results:Among the 1,158 medical devices that adopted the risk intervention management method,the incidences of adverse events in non-surgical departments,surgical departments and diagnosis-related departments were 0.69%(8/1,158),1.90%(22/1,158)and 3.11%(36/1,158),respectively.All were lower than 3.85%(41/1,064),4.98%(53/1,064),and 8.93%(95/1,064)of 1,064 medical devices under the conventional management method,respectively.The differences were statistically significant(x2=25.716,16.143,33.852,P<0.05).The incidence of adverse events at different risk levels of medical devices was lower than that of conventional management method,and the difference was statistically significant(x2=7.625,P<0.05).The qualified rate of cleaning medical device was higher than that of the conventional management method,while the rate of wetting package was lower than that of the conventional management method,and the differences were statistically significant(x2=9.091,17.540,P<0.05).The knowledge levels and total scores of nursing staffs for the composition of medical devices,usage norms,cleaning and sterilization,defect examination,maintenance and precautions of management method with risk intervention were all higher than those of conventional management method,and the differences were statistically significant(t=2.158,2.422,2.544,2.391,2.152,4.528,P<0.05).Conclusion:The intervention measure with the concept of risk management can significantly reduce the incidence of adverse events of medical device,and improve the qualified rate of cleaning medical device,and improve the knowledge level of nursing staffs for medical device.

Objective:To explore the effect and application of interventional measures with concept of risk management in adverse events of medical devices,and assess their effectiveness in reducing the incidence of adverse events and in enhancing patients'safety.Methods:The intervention measures with concept of risk management was adopted to carry out risk assessment and hierarchical management for medical devices,and the operating status of medical devices was monitored in real time,and the standard operating procedures of using medical device were formulated for conducting risk management for medical devices.A total of 2,222 conventional medical devices in clinical use at Qingpu Branch of Zhongshan Hospital Affiliated to Fudan University from January 2022 to March 2024 were selected.Among them,1,064 devices(with random values≤0.48)were managed using conventional methods by stratified random sampling without proportional allocation.Another 1,158 devices(random value>0.48)applied the risk intervention management method.A comparative analysis was conducted on the incidence of adverse events of medical devices,the qualified rate of medical device cleaning and the wet package rate of the two management methods,as well as the score of medical device knowledge level of nursing staff.Results:Among the 1,158 medical devices that adopted the risk intervention management method,the incidences of adverse events in non-surgical departments,surgical departments and diagnosis-related departments were 0.69%(8/1,158),1.90%(22/1,158)and 3.11%(36/1,158),respectively.All were lower than 3.85%(41/1,064),4.98%(53/1,064),and 8.93%(95/1,064)of 1,064 medical devices under the conventional management method,respectively.The differences were statistically significant(x2=25.716,16.143,33.852,P<0.05).The incidence of adverse events at different risk levels of medical devices was lower than that of conventional management method,and the difference was statistically significant(x2=7.625,P<0.05).The qualified rate of cleaning medical device was higher than that of the conventional management method,while the rate of wetting package was lower than that of the conventional management method,and the differences were statistically significant(x2=9.091,17.540,P<0.05).The knowledge levels and total scores of nursing staffs for the composition of medical devices,usage norms,cleaning and sterilization,defect examination,maintenance and precautions of management method with risk intervention were all higher than those of conventional management method,and the differences were statistically significant(t=2.158,2.422,2.544,2.391,2.152,4.528,P<0.05).Conclusion:The intervention measure with the concept of risk management can significantly reduce the incidence of adverse events of medical device,and improve the qualified rate of cleaning medical device,and improve the knowledge level of nursing staffs for medical device.

Objective To explore the influence of continuing nursing care on sexual quality of patients after laparoscopic subtotal hysterectomy.Methods Seventy-eight patients with selective laparoscopic subtotal hysterectomy enrolled from March 2014 to April 2015 were numbered according to their enrollment date,and divided into control group and intervention group randomly.Both groups were conducted laparoscopic subtotal hysterectomy under general anesthesia.After the surgery,the control group was treated with standard nursing care and the intervention group received continuing nursing care beyond the standard nursing care.Participants' sexual quality of 3 months and 6 months after surgery were evaluated using the female sexual function index (FSFI) Results The scores of FSFI of intervention group were significantly higher than those of the control group.Conclusion The continuing nursing care of patients after laparoscopic subtotal hysterectomy can effectively improve patient's short-term sexual quality,which is worth of being applied in gynecology nursing care in the future.

Objective:To investigate the impact of the CD4+CD25nt/hiCD127lo regulatory T cell subset frequency on the immune status and disease progression of Chinese HIV-1 infected individuals.Methods:83 untreated HIV-infected individuals and 312 healthy control individuals of four distinct age groups were enrolled in the research. The CD4+ T cell absolute counts, phenotypes and frequency determination of CD4+CD25nt/hiCD127lo Regulatory T cell subsets was performed on freshly obtained whole blood samples by 3-color immune staining flow cytometry. The HIV-1 specific cellular immune function was test at single cell level by ELISpot. The corresponding plasma viral load was determined by NASBA.Results:The frequency of peripheral CD4+CD25nt/hiCD127lo regulatory T cells of HIV infected individuals in distinct disease progression status was dissimilar in China , and significantly increased in contrast to the healthy controls(P