1.Evaluation index system of training injury rehabilitation quality in military regional rehabilitation center
Ning WANG ; Xiaojie LIU ; Xi HU ; Yinyin LIU ; Qi GAO ; Wei WANG
Journal of Navy Medicine 2025;46(1):6-10
Objective To construct a quality evaluation index system for training injury rehabilitation in military regional rehabilitation centers,so as to promote the systematization and standardization of quality management and provide references for the formulation of relevant policies.Methods The"structure-process-result"three-dimensional quality system model,literature analysis,semi-structured interview,and Delphi method were used to establish the index system,and its reliability and validity were tested.Results Twenty-two inquiry forms were distributed in two rounds of this study,and the effective recovery rates of the two rounds of expert correspondence were 100%.The authority coefficients(Cr)were 0.869 and 0.881,and the Kendall harmony coefficients were 0.230 and 0.339,respectively.The empirical verification showed good reliability and validity.The evaluation index system consisted of 3 primary indexes,12 secondary indexes and 48 tertiary indexes.Conclusion The index system is feasible,reliable and scientific,and can provide a practical and operable evaluation method for the rehabilitation quality management of training injuries.
2.Effects of ultrasound-guided thoracic paravertebral nerve block on postoperative analgesia and risk events in patients with scapular fracture caused by military training
Jie NIE ; Fei WANG ; Yu CAO ; Yanping JIAN
Journal of Navy Medicine 2025;46(1):11-14
Objective To investigate the effects of ultrasound-guided thoracic paravertebral nerve block on postoperative analgesia and risk events in patients with scapular fracture caused by military training.Methods Seventy patients with scapular fracture who were admitted to the Marine Corps Hospital from January 2022 to December 2022 were randomly divided into control group and observation group.All fractures were caused by military training and treated with internal fixation under general anesthesia.The patients in the observation group additionally received ultrasound-guided thoracic paravertebral nerve block.The hemodynamics before and after skin incision,postoperative pain,and adverse events were compared between the two groups.Results The hemodynamic indexes did not significantly change at 5 min after skin incision(P>0.05).Heart rate(HR)and mean arterial pressure(MAP)in the observation group were lower than those in the control group at 5 min after skin incision(P<0.05).The visual analogue scale(VAS)scores at rest and in active state in the observation group were lower than those in the control group at 6 h and 12 h after surgery(P<0.05).The incidence of postoperative adverse events in the observation group was 5.71%,which was lower than that in the control group(25.71%,P<0.05).Conclusion Ultrasound-guided thoracic paravertebral nerve block can reduce the hemodynamic response caused by skin incision,postoperative pain,and the incidence of postoperative adverse events such as nausea and vomiting in patients with scapular fracture caused by military training.
3.Personality traits of the candidates of naval flight cadets in a certain year
Journal of Navy Medicine 2025;46(1):15-20
Objective To analyze the personality traits of the candidates of naval flight cadets,explore the differences among different student sources and different types,and identify the key traits affecting psychological assessment.Methods A total of 945 candidates of naval flight cadets were tested using the Cattell's 16-Personality Factors Questionnaire(16PF)and Navy Recruitment Psychological Selection System.The differences among different student sources and different types were analyzed.The classification model was constructed by support vector machine(SVM)to identify the key indicators of personality traits of suitable candidates.Results There was no significant difference in the personality traits of different student sources except intelligence.There were statistically significant differences in 8 dimensions(A[agreeableness],C[stability],E[confidence],F[excitability],H[courage],M[fantasy],O[anxiety],Q3[self-discipline])and 4 sub factors(X1[adaptive anxiety],X2[introversion and extroversion],Y1[psychological health],Y2[(professional achievement])in personality traits between qualified and eliminated individuals in psychological assessment(P<0.05).There was no significant difference in personality traits between the psychologically qualified subjects with and without carrier flight potential.Gregariousness,assertiveness,imaginativeness,and anxiety were the key indicators to identify the personality traits of flyable subjects.Conclusion Twelve indicators of personality traits related to psychological assessment should be considered for recruiting naval pilots,and the four key indicators of personality traits of flyable subjects should be mainly examined,which is important for effectively screening military flight potential and accurately selecting naval fight cadets.
4.Effect of 3D rotational digital subtraction angiography-guided drug balloon predilation bare-metal stent in patients with vertebral artery origin stenosis
Wei ZHANG ; Hengliang FAN ; Zhiming ZHOU
Journal of Navy Medicine 2025;46(1):27-31
Objective To investigate the effect of 3D rotational digital subtraction angiography(DSA)-guided drug balloon predilation bare-metal stents on vertebral artery origin stenosis(VAOS).Methods A total of 63 VAOS patients who were admitted to Hai'an People's Hospital from May 2020 to December 2022 were selected and divided into two groups according to different treatment methods.There were 16 males and 14 females with a mean age of(52.10±3.62)years in the observation group.There were 19 males and 14 females with a mean age of(52.47±3.85)years in the control group.There was no statistical difference in the basic data between the two groups(P>0.05).The observation group was treated with 3D rotational DSA-guided drug balloon predilation bare-metal stent,while the control group was treated with conventional drug balloon predilation bare-metal stent.The efficacy of the two groups was compared.Results The success rate of operation was 100%(30/30)in the observation group,which was higher than that in the control group(96.97%[32/33],χ2=0.924,P=0.336).There was no significant difference in the stenosis rate between the two groups either before surgery or 3 months after surgery(P>0.05).The hemodynamic level of the initial segment of vertebral artery in the observation group was lower than that in the control group 3 months after surgery(P<0.05).The scores of neurological function and quality of life at 3 months after surgery and the incidence of recurrent stroke at 6 months after surgery in the observation group were lower than those in the control group(P<0.05).Restenosis occurred in 2 cases(6.67%)in the observation group and 9 cases(27.27%)in the control group,and there was significant difference in the incidence of restenosis between the two groups(χ2=4.630,P=0.031).Conclusion 3D rotational DSA-guided drug balloon predilation bare-metal stent can effectively reduce the stenosis rate and the incidence of restenosis,and improve the nerve function and the quality of life of VAOS patients.
5.Quantitative evaluation of the development of fetal conus medullaris and the diagnostic value of terminal caudal vertebral ossification center count in closed spina bifida by three-dimensional ultrasound
Jinghua ZHEN ; Xiangling WU ; Weina ZHOU ; Yan ZHAO ; Chunqing LI
Journal of Navy Medicine 2025;46(1):32-37
Objective To study the development of conus medullaris by quantitative three-dimensional ultrasound in the second and third trimesters of pregnancy,and to analyze the value of terminal caudal vertebral ossification center count in diagnosis of closed spina bifida.Methods A total of 108 normal fetuses in the second and third trimesters of pregnancy who were admitted to Baoding No.1 Central Hospital from January 2019 to March 2024 were selected and assigned to the normal group.The distance between the fetal conus medullaris and the first sacral vertebra,the distance between the end of the conus medullaris and the end of sacrum,and the number of corresponding vertebrae were measured by three-dimensional ultrasound at different gestational weeks.Meanwhile,54 fetuses who were confirmed to have closed spina bifida after delivery were enrolled into the abnormal group.The number of ossification centers on the median sagittal section of the caudal spine was counted and compared between the two groups.The receiver operating characteristic(ROC)curve was drawn to analyze the value of ossification center count of distal caudal vertebrae in diagnosis of closed spina bifida.Results With the increase of gestational weeks,the distance between the fetal conus medullaris and the first sacral vertebra and the distance between the end of the conus medullaris and the end of the sacral bone were gradually increased.The conus medullaris of normal fetuses was mainly located in L1.5,L2 and L2.5,accounting for 85.19%(92/108).The ossification center count of distal caudal vertebra was slightly increased with the increase of gestational weeks in the normal group.At 17-20 gestational weeks,85.71%(12/14)of the ossification center count of distal caudal vertebra was 5 to 7.At 21-28 gestational weeks,100.00%(45/45)of the ossification center count was 6 and more.At week 29 and above,100.00%(45/45)of the ossification center count was more than 7.In the abnormal group,96.30%(52/54)of the fetuses had the ossification center less than 6,and 85.71%(42/49)of the ossification center count was≤5 at 21-32 gestational weeks.There were significant differences in the ossification center count between the two groups at 17-20,21-24,25-28,29-32,and 33-36 gestational weeks(P<0.05).ROC curve showed that,at 17-20,21-24,25-28,29-32,and 33-36 gestational weeks,the area under the curve(AUC)in prediction of closed spina bifida was 0.804,0.744,0.776,0.819,and 0.722 when the ossification center count of distal caudal vertebra was 5.31,4.59,4.81,4.67,and 5.49 as the cut-off value,respectively.Conclusion The conus medullaris moves upward with the increase of gestational weeks in the second and third trimesters of pregnancy.The ossification center count of the distal caudal vertebra is less than 6 in most fetuses with closed spina bifida,which is conducive to screening for closed spina bifida.
6.Comparison of the diagnostic value of 3.0 T MRI HASTE sequence and high-frequency color Doppler ultrasound for high-risk placenta previa combined with placenta accreta
Yue ZHAO ; Xueyang HU ; Lin SUN ; Rui ZHANG ; Zhibao WANG
Journal of Navy Medicine 2025;46(1):38-42
Objective To compare the value of high-field strength MRI half-Fourier single shot turbo spin-echo(HASTE)sequence with high-frequency color Doppler ultrasound for the diagnosis of placenta previa combined with placenta accreta.Methods A total of 116 pregnant women with suspected high-risk placenta previa and placenta accreta who underwent cesarean section at The No.2 Hospital of Baoding from December 2019 to December 2022 were selected as research objects.All parturients took examinations of ultrasound and high-field MRI before surgery.Pathological diagnosis after cesarean section was used as the gold standard for analysis of the consistency between MRI and ultrasound results and pathological results.The value of HASTE sequence and high-frequency ultrasound in diagnosing placenta accreta was compared.Results Pathological results confirmed that 86 patients had high-risk placenta previa and placenta accreta.The positive predictive values of ultrasound,MRI,and ultrasound+MRI in diagnosis of high-risk placenta previa combined with placenta accreta were 93.51%,97.62%,and 98.81%,respectively.The negative predictive values were 64.10%,87.50%,and 90.63%,respectively.The accuracies were 83.62%,94.83%,and 96.55%,respectively.The sensitivities were 83.72%,95.35%,and 96.51%,respectively.The specificities were 83.33%,93.33%,and 96.67%,respectively.The Kappa values for consistency were 0.611,0.868,and 0.912,respectively.The accuracy of MRI in diagnosis of high-risk placenta previa combined with placenta accreta was higher than that of ultrasound(P<0.05).Conclusion 3.0 T MRI HASTE sequence has greater efficacy and higher accuracy in diagnosis of high-risk placenta previa combined with placenta accreta.
7.Metabolomic study of ginsenoside Rh1 against exercise-induced fatigue
Jiaxuan LI ; Xuefang WANG ; Yinglu FENG
Journal of Navy Medicine 2025;46(1):46-51
Objective To investigate the role of ginsenoside Rh1 in regulating the changes of characteristic differential metabolites in rat models of exercise-induced fatigue by gas chromatography-mass spectrometry(GC-MS)and multidimensional statistical analysis,and to clarify the metabolic pathways,so as to provide experimental basis and theoretical support for the effective alleviation of exercise-induced fatigue through Rh1.Methods A total of 27 SPF SD rats were randomly divided into blank control group,model group,and ginsenoside Rh1 group,with 9 rats in each group.A rat exercise-induced fatigue model was established by treadmill exercise.After blood sampling,GC-MS technology,Principal Component Analysis(PCA)and Orthogonal Partial Least Squares(PLS-DA)were used for the identification and screening of differential metabolites,which were further structurally identified in KEGG and HMDB databases.MetPA database was used to construct metabolic pathways and enrich for topological analysis.Results The time to exhaustion in the ginsenoside Rh1 group was significantly longer than that in the model group.Significant differential expression of 8 metabolites(6 significantly decreased and 2 significantly increased)was found in the model group as compared to the blank control group,and 5 metabolic pathways were involved.In the ginsenoside Rh1 group,there were 3 metabolites with significant changes compared with the model group.Citric acid and fatty acid were significantly increased,α-D-glucosamine 1-phosphate was decreased,and the main pathway involved was tricarboxylic acid cycle.Conclusion Rh1 can significantly prolong the time to exhaustion and relieve exercise-induced fatigue in rats,which is closely related to the metabolic pathway of tricarboxylic acid cycle.
8.Preparation of Xuanyang Jiedu cream and its pharmacodynamics
Qinwufeng GU ; Hanwen ZHANG ; Tingru CHEN ; Yuanyuan MENG ; Yunyang WU ; Yanlong YANG
Journal of Navy Medicine 2025;46(1):52-56
Objective To prepare Xuanyang Jiedu cream and to study its pharmacodynamics.Methods The herbal decoction process of Xuanyang Jiedu cream was optimized by orthogonal design method.The prescription of the cream preparation was screened according to the external properties,malleability and stability of cream.Forty normal guinea pig were randomly divided into four groups(10 in each group):blank group,model group,ketoconazole cream group,and Xuanyang Jiedu cream group.The guinea pig model of tinea corporis was established to investigate the efficacy of Xuanyang Jiedu cream in the treatment of superficial fungal disease.Results The optimal extraction conditions were 3 extractions,water added for 20 times,and 1.5 h of extraction time.The number of extractions and the amount of water significantly affected on the extraction process of the liquid extract.The optimized Xuanyang Jiedu cream looked smooth and creamy,with moderate viscosity and good stabilities of centrifuge,cold and heat resistance.After 14 d treatment,there were still obvious erythema,scales and papules on the lesions in the model group.The scores of erythema,scales and papules in the Xuanyang Jiedu cream group and the ketoconazole cream group were lower than those in the model group(P<0.05).Conclusion Xuanyang Jiedu cream has antifungal activity and may be a new treatment for skin superficial mycosis.
9.Influence of heparin sodium on early recovery after lumbar surgery and the construction of prediction model for postoperative deep vein thrombosis
Qing ZHAO ; Lijun ZHAI ; Minghua WU ; Ruli FAN
Journal of Navy Medicine 2025;46(1):57-62
Objective To explore the influence of heparin sodium on early recovery after lumbar surgery and the risk factors of deep vein thrombosis(DVT)of lower extremities,and build a prediction model for DVT after lumbar surgery based on the risk factors.Methods A total of 276 patients who underwent lumbar surgery and were treated with heparin sodium in The First Affiliated Hospital of Naval Medical University from January 2020 to January 2023 were selected as research objects.Activated partial thromboplastin time(APTT),prothrombin time(PT)and functional indexes of lumbar spine were recorded before and after treatment.DVT of lower extremities was detected by ultrasound during postoperative hospitalization,and then the patients were divided into DVT group and non-DVT group.The clinical data and laboratory indicators of all patients were collected.The risk factors of DVT after lumbar surgery were analyzed by logistic regression analysis.A postoperative DVT risk prediction model based on Logistic regression analysis was constructed and validated.Results APTT and PT after operation were higher than those before operation(P<0.05).The score of Oswestry Disability Index(ODI)3 months after surgery was lower than that before surgery(t=30.661,P<0.05).The incidence of DVT was 14.86%(41/276).Blood transfusion,bed rest≥5 d,proportion of general anesthesia,intraoperative blood loss,body mass index(BMI)and D-dimer level in the DVT group were higher than those in the non-DVT group(P<0.05).Logistic regression analysis showed that intraoperative blood loss,BMI,abnormal D-dimer level,intraoperative blood transfusion,and bed rest≥5 d were all risk factors for DVT after lumbar surgery(P<0.05).logit(P)=9.762+1.425×intraoperative blood loss+1.212×BMI+0.856×intraoperative blood transfusion+1.105×bed rest+1.671×D-dimer.Hosmer-Lemeshow test showed that the model had a high goodness of fit(χ2=4.025,P=0.473).The sensitivity,specificity and area under curve(AUC)of the constructed prediction model for postoperative DVT were 91.80%,70.40%and 0.836(95%CI:0.698-0.948),respectively.Conclusion Heparin sodium can improve blood circulation and lumbar function and prolong clotting time in patients with lumbar surgery.Intraoperative blood loss,BMI,abnormal D-dimer,intraoperative blood transfusion,and bed rest≥5 d are all risk factors for the occurrence of DVT after lumbar surgery.The prediction model based on the above risk factors has high predictive value for the occurrence of DVT after lumbar surgery.
10.Construction and application of nomogram prediction model for trial of labor after cesarean
Yunfeng QIAN ; Guoqing CHENG ; Xuemei DENG ; Dandan WEI
Journal of Navy Medicine 2025;46(1):63-67
Objective To explore the influencing factors of the failure in trial of labor after cesarean(TOLAC),construct and verify a prediction model for the risk of TOLAC.Methods The clinical data of 273 pregnant women who underwent TOLAC in The First Affiliated Hospital of Naval Medical University from 2019 to 2022 were retrospectively analyzed.Logistic regression was used to analyze influencing factors of the failure in TOLAC,and a nomogram model was established for individualized risk assessment.The best threshold of failure risk of TOLAC was evaluated by the decision-making curve and clinical influence curve.Results There were statistically significant differences in the age,gestational week,body mass index(BMI)before delivery,time to the last cesarean,cervical Bishop score and delivery times between the successful trial delivery group and the failed trial delivery group.The best intervention threshold was 0.72,that is,vaginal trial delivery should to be stopped when the risk of TOLAC failure was more than 72%as evaluated by the prediction model.Conclusion Age,gestational week,BMI before delivery,time to the last cesarean,Bishop score of cervix and delivery times are influencing factors for TOLAC failure.The prediction model based on these factors can provide a quantifiable TOLAC risk for pregnant women.

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