The present case illustrates an arteriovenous malformation of the cheek in a 25-year-old male. The clinical presentation, radiographic findings, differential diagnosis, treatment and histopathologic description are presented. Diagnosis of the lesion was confirmed by angiography, and the lesion was treated by angiographically controlled vascular embolization followed by complete surgical excision.
Adult ; Angiography ; Arteriovenous Malformations* ; Cheek ; Diagnosis ; Diagnosis, Differential ; Humans ; Male

Leiomyosarcoma is extremely rare in the oral cavity and especially in the mandible. At first, the case of this report was diagnosed as odontogenic fibroma but after approximately 3.5 years, it was diagnosed as leiomyosarcoma. Conventional radiograph of the first time showed an ill-defined radiolucent lesion in the mandible. After local recurrence, CT images showed a large irregular soft tissue mass with some necrotic areas. These findings were not specific for leiomyosarcoma, but they suggested that this lesion was a recurrent soft tissue sarcoma. Histopathological examinations using H & E staining, immunohistochemical staining and Masson's trichrome staining confirmed this case as leiomyosarcoma. Deciding its malignany or benignancy, defining the tumor extent and its relationship to the surrounding anatomic structures, and evaluating the distant metastasis are more important role of radiographic examination than finding out the name of disease.
Fibroma ; Leiomyosarcoma* ; Mandible* ; Mouth ; Neoplasm Metastasis ; Recurrence ; Sarcoma

Malignant fibrous histiocytoma is one of the most common soft tissue sarcomas in late adult life, but its incidence in oral and maxillofacial region is extremely rare. We report a case of malignant fibrous histiocytoma which occurred in the infratemporal fossa. Conventional radiograph of this case showed an ill-defined radiolucent lesion in the alveolar bone of the right maxillary first molar area, the lateral wall of the maxillary sinus, and the ascending ramus of mandible. MRI demonstrated well defined mass of intermediate signal intensitiy in T1 weighted images but T2 weighted images showed two distinctive regions of different characteristics. Infratemporal portion of the lesion was of hyperintense signal but under that region, the signal intensity decreased clearly, which might mean this case composed of two different subtypes, though it couldn't be confirmed by histopathological examination. Biopsy was taken in the only soft tissue of the maxillary posterior alveolar region and confirmed the lesion as the storiform-pleomorphic type of malignant fibrous histiocytoma. Histopathological subtype was well consistent with the relatively aggressive imaging findings of that region. We expect more detailed analysis of the nature of malignant fibrous histiocytoma with improvement of the imaging modality and the identification of the relationship between diagnostic imaging and histopathologic findings.
Adult ; Biopsy ; Diagnostic Imaging ; Histiocytoma, Malignant Fibrous* ; Humans ; Incidence ; Magnetic Resonance Imaging ; Mandible ; Maxillary Sinus ; Molar ; Sarcoma

PURPOSE: To determine the clinical and radiological features of peripheral osteoma of the mandible (POM) in a Korean population and to compare with previous reports. MATERIALS AND METHODS: Sixteen cases of POM found in 15 Korean patients who visited Seoul National University Dental Hospital between 1980 and 1998 were reviewed to determine their clinical and radiological features. RESULTS: The 15 patients, five males and ten females, ranged in age from 22 to 69 years, with a mean age of 40.7 years. Six POMs were located on the buccal side of the mandibular body and five on the lingual aspect of the mandibular body and five on the lower border of the mandible. The duration of the lesion ranged between 1 and 10 years. The size of the lesions, in their great diameter, ranged from 6 mm to 26 mm, with a mean of 14.1 mm. Six POMs were pedunculated, nine sessile, and one bell-shaped. Eleven POMs were compact types and five were cancellous ones. CONCLUSION: The clinical and radiological features of these Korean series were broadly consistent with those of non-Korean populations reported previously. The principal difference was that all POMs under 35 year-old age were compact types.
Adult ; Female ; Humans ; Male ; Mandible* ; Osteoma* ; Seoul

Osteopetrosis is an uncommon hereditary bone disorder whose prominent radiologic feature characterized by increased bone density. The authors reported a 7-year-old male patient who referred from local dental clinic for dental problems such as early exfoliation of deciduous teeth(#54,73,83) and delayed eruption of permanent teeth(#31,41,36,46). The patient appeared as a poorly developed. Dental X-ray films showed early exfoliation of deciduous teeth, delayed eruption of permanent teeth, and rampant caries. Lateral view of skull demonstrated increased opacity of calvarium, facial bones, and skull base. Generally the skeletal density is greatly increased throughout all bones. Facial CT showed poor development of paranasal sinuses and mastoid air cells. No hematopoietic and neurologic complications such as anemia, thrombocytopenia, blindness and deafness were found. Also mental retardation was not found. The final diagnosis of this case was a osteopetrosis tarda. Sometimes patient with osteopetrosis tarda may be developed dental problems prior to severe systemic symptoms. The dentist can be the first clinician to see the patient. It is very important for the dentist to have the knowledge of the osteopetrosis and to care the patient's dental problems to prevent complication such as osteomyelitis of jaws.
Anemia ; Blindness ; Bone Density ; Child ; Deafness ; Dental Clinics ; Dentists ; Diagnosis ; Facial Bones ; Growth Disorders ; Humans ; Intellectual Disability ; Jaw ; Male ; Mastoid ; Osteomyelitis ; Osteopetrosis* ; Paranasal Sinuses ; Skull ; Skull Base ; Thrombocytopenia ; Tooth ; Tooth Eruption ; Tooth, Deciduous ; X-Ray Film

PURPOSE: This study was to evaluate the effects of Aloe, Gelfoam, and Plaster of Paris on bone healing. MATERIALS AND METHODS: Four experimental defects were created for placement of the three materials in the right femur of dogs. One defect served as an empty control site. The evaluation was performed at 1-, 6-, and 12-weeks by light microscopy and NIH image program. RESULTS: Radiographic and Histologic examinations showed new bone formation in the presence of Aloe, Gelfoam, and Plaster of Paris and similar bone healing reactions. CONCLUSION: On the basis of these findings, it was concluded that Aloe, Gelfoam, and Plaster of Paris may be adequate agents for use in bone procurement.
Aloe* ; Animals ; Calcium Sulfate ; Dogs ; Femur ; Gelatin Sponge, Absorbable* ; Microscopy ; Osteogenesis*

OBJECTIVES: To evaluate the anatomic variations of the paranasal sinuses on computed tomographs. MATERIALS AND METHODS: The author examined the CT images of the paranasal sinuses retrospectively in 500 patients who visited Chonbuk National University Hospital between January 1996 and December 1997. RESULTS: The highest incidence of anatomic variation of the paranasal sinuses in bilateral structures was agger nasi cell(73.2%), followed by concha bullosa(31.1%), Onodi cell(24.0%), Haller cell(19.8%), maxillary sinus septum(13.0%), paradoxical middle turbinate(2.5%), pneumatized uncinate process(2.0%), and bent uncinate process. The highest incidence of anatomic variation in midline structures was nasal septum deviation(53.2%), followed by nasal septumaerated(29.4%), bulla galli(24.7%) asymmetric intersphenoid septum(22.3%), and nasal septum spur(13.8%). The correlation between anatomic variation and paranasal sinusitis was not found. CONCLUSIONS: The results of this study will aid in the diagnosis and treatment of paranasal sinus diseases, especially in the treatment planning before functional endoscopic surgery.
Anatomic Variation* ; Diagnosis ; Humans ; Incidence ; Jeollabuk-do ; Maxillary Sinus ; Nasal Septum ; Paranasal Sinus Diseases ; Paranasal Sinuses ; Retrospective Studies ; Sinusitis

OBJECTIVES: The purpose of this study was to evaluate the computed tomographic (CT) images of the paranasal sinusitis(PNS). MATERIALS AND METHODS: The author examined the extent and the recurring patterns of the paranasal sinusitis and some important anatomic landmarks. The author analyzed PNS images retrospectively in 500 patients who visited Chonbuk National University Hospital between January 1996 and December 1997. RESULTS: The most frequently affected sinus was maxillary sinus(82.9%), followed by anterior ethmoid sinus(67.9%), posterior ethmoid sinus(48.9%), frontal sinus(42.0%) and sphenoid sinus(41.4%). The characteristic features of CT images of the sinusitis were sinus opacification(22.4%), mucoperiosteal thickening(34.3%), and polyposis(2.0%). Sinonasal inflammatory diseases were categorized into 5 patterns according to Babbel's classification. They were 1) infundibular(13.0%), 2) ostiomeatal unit(67.4%), 3)sphenoethmoidal recess(13.0%), 4) sinonasal polyposis(9.6%) and 5) unclassifiable patterns(18.0%). The incidences of contact between sinus and optic nerve were as follows ; the incidences of contact with posterior ethmoid sinus, sphenoid sinus, both posterior sinuses were 11.4%, 66.8%, 6.3%, respectively. The incidences of contact between sphenoid sinus and maxillary nerve, vidian nerve, internal carotid artery were 74.5%, 79.2%, 45.1% respectively. The incidences of pneumatization of the posterior ethmoid sinus were as follows ; normal 70.6% and overriding type 29.4%. The incidences of sphenoid sinus pneumatization were as follows ; normal 56.9% , rudimentary 12.5%, pterygoid recess 22.7%, anterior clinoid recess 2.7%, and both pterygoid and anterior clinoid recess 5.2%. CONCLUSIONS: The inflammatory sinonasal diseases were classified into five patterns using the CT of PNS, which was proven to be an excellent imaging modality providing detailed information about mucosal abnormality, pathologic patterns and the proximity of the important structures to the posterior paranasal sinuses. This result will aid in the interpretation of CT of PNS functionally and systemically.
Anatomic Landmarks ; Carotid Artery, Internal ; Classification ; Ethmoid Sinus ; Humans ; Incidence ; Jeollabuk-do ; Maxillary Nerve ; Optic Nerve ; Paranasal Sinuses ; Retrospective Studies ; Sinusitis* ; Sphenoid Sinus

PURPOSE: To determine normal CT number range of parotid gland by analyzing the change by age increase and the difference among individuals and between both sexes in CT number of normal parotid gland. MATERIALS AND METHODS: 134 subjects who took the CT scan between the period of Jan. 1996 and Dec. 1997 at Yonsei University, Dental Hospital were selected. Criteria for selection were that the patients must be within the normal range clinically and radiologically, and the entire parotid gland on the axial view must be shown. Among the axial views, the one showing the greatest parotid gland size was selected and its CT number was recorded. Also, CT numbers from both masseter muscle were recorded as its control. RESULTS: There was statistically significant correlation between CT number of right and left of parotid glands and masseter muscles. With the increase of age, there is a significant decrease in the CT number of parotid gland (p<0.05). There was no statistically significant difference in CT number between sexes except the 7th decade and beyond age group of parotid gland (p>0.05). CONCLUSION: As age increases, CT number of parotid gland has a tendency to decrease, and there is no significant difference in the CT numbers between left and right parotid gland. Therefore in the CT scan of patients suspected of having an salivary gland disease of the parotid gland, to consider normal range of the age-dependent CT numbers of parotid gland and compare the CT numbers of the right and left parotid gland might be useful in diagnosing the disease.
Aging ; Humans ; Masseter Muscle ; Parotid Gland* ; Reference Values ; Salivary Gland Diseases ; Tomography, X-Ray Computed

PURPOSE: The study was aimed to detect the differences in the cell viability and the apoptosis induction after irradiation on normal and tumorigenic cells. MATERIALS AND METHODS: The study, that was generated for two human normal cells(RHEK, HGF-1) and two human tumor cells(KB, HT-1080), was tested using MTT assay at 1 day and 3 day after irradiation and TUNEL assay under confocal laser scanning microscope at 1 day after irradiation. Single irradiation of 0.5, 1, 2, 4, and 8 Gy were applied to the cells. The two fractions of 1, 2, 4, and 8 Gy were separated with a 4 hour time interval. The irradiation was done with 5.38 Gy/min dose rate using Cs-137 irradiator at room temperature. RESULTS AND CONCLUSIONS: 1. In 3-day group, the cell viability of HGF-1 cell was significantly decreased at 2, 4 and 8 Gy irradiation, the cell viability of KB cell was significantly decreased at 8 Gy irradiation and the cell viability of HT-1080 cell was significantly decreased at 4 and 8 Gy irradiation. 2. There was significant difference between RHEK and KB cell line in the cell viability of 3-day group at 8 Gy irradiation. There was significant difference between RHEK and HGF-1 cell line in the cell viability of 3-day group at 4 and 8 Gy irradiation. 3. There was a significantly decreased cell viability in 3-day group than those in 1-day group at 2, 4 and 8 Gy on HGF-1 cell, at 4 and 8 Gy on HT-1080 cell, at 8 Gy on KB cell. 4. We could detect DNA fragmented cells only on KB cell. Number of apoptotic cells of KB cell was significantly increased at 4 and 8 Gy irradiation. However, there was no correlation between cell viability and apoptosis. 5. On all 4 cell lines, there were no differences between single and split irradiation method in cell viability and apoptosis.
Apoptosis* ; Cell Line ; Cell Survival* ; DNA ; Humans ; In Situ Nick-End Labeling ; KB Cells ; Radiation Dosage*