1.Efficacy of early initiation of rehabilitation on motor function and functional recovery of patients with acute intracerebral hemorrhage: A meta-analysis.
John Emmanuel A. CORPUZ ; Jose Antonio Luis PANTANGCO
Philippine Journal of Neurology 2025;28(2):40-48
BACKGROUND
Acute ICH represents a serious form of stroke, associated with high morbidity and mortality. Early rehabilitation has been recommended in order to improve motor function recovery and functional independence of the patients with ICH. However, the timing at which rehabilitation should be initiated remains unclear.
OBJECTIVESThis study aims to determine the effectiveness of early rehabilitation in motor function recovery and functional independence as well as to investigate the ideal timing for initiating rehabilitation post-ICH.
METHODSFour RCTs were retrieved in this meta-analysis (Bai et al – 364 patients, Liu et al – 243 patients, Yen et al – 60 patients, Zhu et al – 84 patients). Selection criteria included early rehabilitation intervention for acute ICH patients, with measurable objective assessment of motor function and evaluation of ADLs at 1 and 3 months post-rehabilitation. Data extraction was done from the selected studies, followed by statistical analysis, using a random effects model, calculating the SMD with 95% CI.
RESULTSEarly rehabilitation significantly improved motor function at 1 month [SMD = 0.55, 95% CI 0.09, 1.00, p = 0.02] and independence in ADLs at 1 month [SMD = 0.57, 95% CI 0.10, 1.05, p = 0.02]. However, this did not persist at 3 months [SMD = 0.17, 95% CI 0.00, 0.35, p = 0.05].
CONCLUSIONResults of this meta-analysis support that early rehabilitation within 72 hours post-ICH significantly improved motor recovery and independence in ADLs at 1 month but uncertainties still surround benefits at 3 months.
Human ; Cerebral Hemorrhage ; Hemorrhage ; Rehabilitation ; Patients
2.Efficacy of early initiation of rehabilitation on motor function and functional recovery of patients with acute intracerebral hemorrhage: A meta-analysis.
John Emmanuel A. CORPUZ ; Jose Antonio Luis PANTANGCO
Philippine Journal of Neurology 2025;28(2):40-48
BACKGROUND
Acute ICH represents a serious form of stroke, associated with high morbidity and mortality. Early rehabilitation has been recommended in order to improve motor function recovery and functional independence of the patients with ICH. However, the timing at which rehabilitation should be initiated remains unclear.
OBJECTIVESThis study aims to determine the effectiveness of early rehabilitation in motor function recovery and functional independence as well as to investigate the ideal timing for initiating rehabilitation post-ICH.
METHODSFour RCTs were retrieved in this meta-analysis (Bai et al – 364 patients, Liu et al – 243 patients, Yen et al – 60 patients, Zhu et al – 84 patients). Selection criteria included early rehabilitation intervention for acute ICH patients, with measurable objective assessment of motor function and evaluation of ADLs at 1 and 3 months post-rehabilitation. Data extraction was done from the selected studies, followed by statistical analysis, using a random effects model, calculating the SMD with 95% CI.
RESULTSEarly rehabilitation significantly improved motor function at 1 month [SMD = 0.55, 95% CI 0.09, 1.00, p = 0.02] and independence in ADLs at 1 month [SMD = 0.57, 95% CI 0.10, 1.05, p = 0.02]. However, this did not persist at 3 months [SMD = 0.17, 95% CI 0.00, 0.35, p = 0.05].
CONCLUSIONResults of this meta-analysis support that early rehabilitation within 72 hours post-ICH significantly improved motor recovery and independence in ADLs at 1 month but uncertainties still surround benefits at 3 months.
Human ; Cerebral Hemorrhage ; Hemorrhage ; Rehabilitation ; Patients
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