Background: We have developed the Korean safety ladder as part of development of new safety technologies that can be accepted in industrial sites and would like to introduce the testing process to secure safety. Methods: The test load and horizontal force prescribed by ANSI A14.7 and EN131-7 standards for only the overturning stability test were applied to calculate the weight required for securing overturning stability according to standards and installation of outrigger with the variables of the height of platform, the angle of inclination of the worker, and the size of the platform. Results: The weight of a Korean safety ladder required for securing overturning stability according to the height is as follows: as mentioned by the ANSI A14.7, it is stable regardless of the weight when an outrigger. By the EN131-7 standard, a 5-step ladder is stable regardless of the weight, but 54 kg or more of weight is required for an 8-step ladder when an outrigger is installed. When there is no outrigger, 122 kg and 251 kg are required for 5-step and 8-step ladders, respectively. Conclusion It is necessary to restrict inclined working on the platform at less than 66° of inclination angle by the EN131-7 standards and secure 43 kg or more of weight in the minimum width of a platform of 400 mm or expand the ladder width or open length of the outrigger.

Interleukin-8(IL-8) has been implicates in intraocular inflammation and shown to be a potent chemoattractant for neutrophil, we investigated if IL- 8 has a role in endotoxin induced uveitis(EIU). Mouse monoclonal neutralizing antibody to rabbit recombinant IL-8(gammagammaIL-8)(gammagammaIL-8 and anti IL-8, both generous gifts from Genetech) or mouse IgG2a were given by intravitreal injection to try to modify EIU in New Zealand White rabbits. Antibody to IL-8 tended to reduce aqueous humor cell counts, but the differences were not statistically significant. Anti-IL8 reduced cell counts by 34%(3.8+/-2.9x10(6) cells/ml anti IL-8 treatment vs. 5.4+/-5.5x10 cells/ml IgG2a control, p=0.26 by student t-test). The intravitreal injection of gammagammaIL-8 resulted in a small dose dependent number of infiterating cells in the aqueous and vitreous humor. Taken together, our results cannot exclude a role for IL-8 in acute onset EIU, but the contribution appears to be minor.
Animals ; Antibodies, Neutralizing ; Aqueous Humor ; Cell Count ; Gift Giving ; Humans ; Immunoglobulin G ; Inflammation ; Interleukin-8* ; Intravitreal Injections ; Mice ; Neutrophils ; Rabbits ; Uveitis* ; Vitreous Body