With the increasing use of CAD-CAM (computer-aided design-computer-aided manufacturing) methods for prosthesis fabrication, utilization of virtual articulators in CAD software has also increased. Among the various methods of positioning the maxilla in a virtual articulator, there are techniques that utilize CBCT (cone-beam computed tomography) or facial scans without the use of a facebow.In this case, a full-mouth rehabilitation was planned for a patient who exhibited multiple crown fractures and occlusal plane disharmony through maxillary complete denture and mandibular fixed prosthetic restoration. Radiopaque markers were added to the duplicated maxillary temporary denture to take closed-mouth impression, which was then scanned and positioned on the CBCT. On CBCT, hinge axis connecting the medial poles of both mandibular condyles along with the Frankfort horizontal plane was designated and utilized to perform virtual articulator mounting. Maxillary complete denture and mandibular fixed prostheses were fabricated, resulting in satisfactory aesthetic and functional outcomes.

With the increasing use of CAD-CAM (computer-aided design-computer-aided manufacturing) methods for prosthesis fabrication, utilization of virtual articulators in CAD software has also increased. Among the various methods of positioning the maxilla in a virtual articulator, there are techniques that utilize CBCT (cone-beam computed tomography) or facial scans without the use of a facebow.In this case, a full-mouth rehabilitation was planned for a patient who exhibited multiple crown fractures and occlusal plane disharmony through maxillary complete denture and mandibular fixed prosthetic restoration. Radiopaque markers were added to the duplicated maxillary temporary denture to take closed-mouth impression, which was then scanned and positioned on the CBCT. On CBCT, hinge axis connecting the medial poles of both mandibular condyles along with the Frankfort horizontal plane was designated and utilized to perform virtual articulator mounting. Maxillary complete denture and mandibular fixed prostheses were fabricated, resulting in satisfactory aesthetic and functional outcomes.

With the increasing use of CAD-CAM (computer-aided design-computer-aided manufacturing) methods for prosthesis fabrication, utilization of virtual articulators in CAD software has also increased. Among the various methods of positioning the maxilla in a virtual articulator, there are techniques that utilize CBCT (cone-beam computed tomography) or facial scans without the use of a facebow.In this case, a full-mouth rehabilitation was planned for a patient who exhibited multiple crown fractures and occlusal plane disharmony through maxillary complete denture and mandibular fixed prosthetic restoration. Radiopaque markers were added to the duplicated maxillary temporary denture to take closed-mouth impression, which was then scanned and positioned on the CBCT. On CBCT, hinge axis connecting the medial poles of both mandibular condyles along with the Frankfort horizontal plane was designated and utilized to perform virtual articulator mounting. Maxillary complete denture and mandibular fixed prostheses were fabricated, resulting in satisfactory aesthetic and functional outcomes.

Tuberculous pericarditis is an extrapulmonary manifestation of tuberculosis that is most commonly associated with pericardial thickening, effusion, and calcification. We present a case of tuberculous pericarditis mimicking a malignant pericardial tumor in a 77-year-old male. CT revealed an irregular and nodular pericardial thickening. MRI revealed high signal intensity on T1-weighted fat-suppressed images and peripheral rim enhancement after gadolinium administration. MRI can be helpful in determining the differential diagnoses in cases of tuberculous pericarditis with nonspecific imaging findings.

Tuberculous pericarditis is an extrapulmonary manifestation of tuberculosis that is most commonly associated with pericardial thickening, effusion, and calcification. We present a case of tuberculous pericarditis mimicking a malignant pericardial tumor in a 77-year-old male. CT revealed an irregular and nodular pericardial thickening. MRI revealed high signal intensity on T1-weighted fat-suppressed images and peripheral rim enhancement after gadolinium administration. MRI can be helpful in determining the differential diagnoses in cases of tuberculous pericarditis with nonspecific imaging findings.

With the increasing use of CAD-CAM (computer-aided design-computer-aided manufacturing) methods for prosthesis fabrication, utilization of virtual articulators in CAD software has also increased. Among the various methods of positioning the maxilla in a virtual articulator, there are techniques that utilize CBCT (cone-beam computed tomography) or facial scans without the use of a facebow.In this case, a full-mouth rehabilitation was planned for a patient who exhibited multiple crown fractures and occlusal plane disharmony through maxillary complete denture and mandibular fixed prosthetic restoration. Radiopaque markers were added to the duplicated maxillary temporary denture to take closed-mouth impression, which was then scanned and positioned on the CBCT. On CBCT, hinge axis connecting the medial poles of both mandibular condyles along with the Frankfort horizontal plane was designated and utilized to perform virtual articulator mounting. Maxillary complete denture and mandibular fixed prostheses were fabricated, resulting in satisfactory aesthetic and functional outcomes.

Tuberculous pericarditis is an extrapulmonary manifestation of tuberculosis that is most commonly associated with pericardial thickening, effusion, and calcification. We present a case of tuberculous pericarditis mimicking a malignant pericardial tumor in a 77-year-old male. CT revealed an irregular and nodular pericardial thickening. MRI revealed high signal intensity on T1-weighted fat-suppressed images and peripheral rim enhancement after gadolinium administration. MRI can be helpful in determining the differential diagnoses in cases of tuberculous pericarditis with nonspecific imaging findings.

With the increasing use of CAD-CAM (computer-aided design-computer-aided manufacturing) methods for prosthesis fabrication, utilization of virtual articulators in CAD software has also increased. Among the various methods of positioning the maxilla in a virtual articulator, there are techniques that utilize CBCT (cone-beam computed tomography) or facial scans without the use of a facebow.In this case, a full-mouth rehabilitation was planned for a patient who exhibited multiple crown fractures and occlusal plane disharmony through maxillary complete denture and mandibular fixed prosthetic restoration. Radiopaque markers were added to the duplicated maxillary temporary denture to take closed-mouth impression, which was then scanned and positioned on the CBCT. On CBCT, hinge axis connecting the medial poles of both mandibular condyles along with the Frankfort horizontal plane was designated and utilized to perform virtual articulator mounting. Maxillary complete denture and mandibular fixed prostheses were fabricated, resulting in satisfactory aesthetic and functional outcomes.

Objective: The Scales for Outcomes in Parkinson’s Disease–Cognition (SCOPA-Cog) was developed to assess cognition in patients with Parkinson’s disease (PD). In this study, we aimed to evaluate the validity and reliability of the Korean version of the SCOPACog (K-SCOPA-Cog). Methods: We enrolled 129 PD patients with movement disorders from 31 clinics in South Korea. The original version of the SCOPA-Cog was translated into Korean using the translation-retranslation method. The test–retest method with an intraclass correlation coefficient (ICC) and Cronbach’s alpha coefficient were used to assess reliability. Spearman’s rank correlation analysis with the Montreal Cognitive Assessment-Korean version (MOCA-K) and the Korean Mini-Mental State Examination (K-MMSE) were used to assess concurrent validity. Results: The Cronbach’s alpha coefficient was 0.797, and the ICC was 0.887. Spearman’s rank correlation analysis revealed a significant correlation with the K-MMSE and MOCA-K scores (r = 0.546 and r = 0.683, respectively). Conclusion Our results demonstrate that the K-SCOPA-Cog has good reliability and validity.

Tixagevimab/cilgavimab is a monoclonal antibody used to prevent coronavirus disease 2019 among immunocompromised hosts and maintained neutralizing activity against early omicron variants. Omicron BN.1 became a dominant circulating strain in Korea early 2023, but its susceptibility to tixagevimab/cilgavimab is unclear. We conducted plaque reduction neutralization test (PRNT) against BN.1 in a prospective cohort (14 patients and 30 specimens). BN.1 PRNT was conducted for one- and three-months after tixagevimab/ cilgavimab administration and the average PRNT ND 50 of each point was lower than the positive cut-off value of 20 (12.9 ± 4.5 and 13.2 ± 4.2, respectively, P = 0.825). In the paired analyses, tixagevimab/cilgavimab-administered sera could not actively neutralize BN.1 (PRNT ND 50 11.5 ± 2.9, P = 0.001), compared with the reserved activity against BA.5 (ND 50 310.5 ± 180.4). Unlike virus-like particle assay, tixagevimab/cilgavimab was not active against BN.1 in neutralizing assay, and would not be effective in the present predominance of BA.2.75 sublineages.