OBJECTIVE To analyze the status and characteristics of hospital-associated infection in a three-A hospi-tal from 2023 to 2024,and to identify directions for intervention in hospital-associated infection.METHODS The hospital-associated infection data of a three-A hospital from 2023 to 2024 were analyzed,including the overall trend of hospital-associated infection,the top three departments with the highest hospital-associated infection rates,the distribution of pathogens,infection sites and patient ages.RESULTS From 2023 to 2024,a total of 145 915 patients were monitored,with 1 673 cases of hospital-associated infection,resulting in a hospital-associat-ed infection rate of 1.15％.The hospital-associated infection rate in 2024 was 1.06％(831/78 284),which was lower than that in 2023(P=0.001).The top three departments with the highest hospital-associated infection rates were the intensive care unit,the emergency intensive care unit(EICU)and the cadre ward.Among the de-tected pathogens,gram-negative bacteria were predominantly Acinetobacter baumannii(26.21％),gram-positive bacteria were predominantly Staphylococcus aureus(4.86％)and fungi were predominantly Candida glabrata(13.89％).There were statistically significant differences in the proportions of Proteus vulgaris,Serratia lique-faciens,Burkholderia cepacia and gram-positive bacteria between the two years(P＜0.05).The main hospital-associated infection sites were the respiratory tract,urinary tract and surgical site.The hospital-associated infec-tion rate was high among elderly patients,particularly in the cadre ward.CONCLUSIONS The departments with high incidence of hospital-associated infection are the intensive care unit,EICU and cadre ward.The main patho-gen is A.baumannii,with the respiratory tract being the primary site of infection.It is necessary to strengthen prevention and control measures for high-risk departments,key pathogens and common infection sites to effective-ly reduce the incidence of hospital-associated infection.

OBJECTIVE To analyze the status and characteristics of hospital-associated infection in a three-A hospi-tal from 2023 to 2024,and to identify directions for intervention in hospital-associated infection.METHODS The hospital-associated infection data of a three-A hospital from 2023 to 2024 were analyzed,including the overall trend of hospital-associated infection,the top three departments with the highest hospital-associated infection rates,the distribution of pathogens,infection sites and patient ages.RESULTS From 2023 to 2024,a total of 145 915 patients were monitored,with 1 673 cases of hospital-associated infection,resulting in a hospital-associat-ed infection rate of 1.15％.The hospital-associated infection rate in 2024 was 1.06％(831/78 284),which was lower than that in 2023(P=0.001).The top three departments with the highest hospital-associated infection rates were the intensive care unit,the emergency intensive care unit(EICU)and the cadre ward.Among the de-tected pathogens,gram-negative bacteria were predominantly Acinetobacter baumannii(26.21％),gram-positive bacteria were predominantly Staphylococcus aureus(4.86％)and fungi were predominantly Candida glabrata(13.89％).There were statistically significant differences in the proportions of Proteus vulgaris,Serratia lique-faciens,Burkholderia cepacia and gram-positive bacteria between the two years(P＜0.05).The main hospital-associated infection sites were the respiratory tract,urinary tract and surgical site.The hospital-associated infec-tion rate was high among elderly patients,particularly in the cadre ward.CONCLUSIONS The departments with high incidence of hospital-associated infection are the intensive care unit,EICU and cadre ward.The main patho-gen is A.baumannii,with the respiratory tract being the primary site of infection.It is necessary to strengthen prevention and control measures for high-risk departments,key pathogens and common infection sites to effective-ly reduce the incidence of hospital-associated infection.