Purpose: The study aimed to identify the factors impacting nurse unit managers’ knowledge and ability importance of managerial competencies. Methods: The participants were 200 nurse unit managers who worked at general hospitals or tertiary care hospitals. Data were collected from February 1 to June 30, 2021, and analyzed using descriptive statistics, independent t-test, paired t-test, ANOVA, and stepwise multiple regression analysis with IBM SPSS/WIN 26.0. Results: Nurse unit managers perceived the ability of managerial competencies to be less important than knowledge thereof. Overall, nurse unit managers perceived the importance of human and technical competencies as the most important, while the importance of financial managerial competency as the lowest. The significant predictors of knowledge and ability importance of managerial competencies were ‘nursing environment’ and ‘research experience’, and the input variables explained 34% of knowledge importance and 25% of ability importance. Conclusion Nurse administrators should continue to pay attention to the nursing environment, provide nursing unit managers with opportunities to conduct various research and provide related education.

Purpose: The study aimed to identify the factors impacting nurse unit managers’ knowledge and ability importance of managerial competencies. Methods: The participants were 200 nurse unit managers who worked at general hospitals or tertiary care hospitals. Data were collected from February 1 to June 30, 2021, and analyzed using descriptive statistics, independent t-test, paired t-test, ANOVA, and stepwise multiple regression analysis with IBM SPSS/WIN 26.0. Results: Nurse unit managers perceived the ability of managerial competencies to be less important than knowledge thereof. Overall, nurse unit managers perceived the importance of human and technical competencies as the most important, while the importance of financial managerial competency as the lowest. The significant predictors of knowledge and ability importance of managerial competencies were ‘nursing environment’ and ‘research experience’, and the input variables explained 34% of knowledge importance and 25% of ability importance. Conclusion Nurse administrators should continue to pay attention to the nursing environment, provide nursing unit managers with opportunities to conduct various research and provide related education.

Purpose: The study aimed to identify the factors impacting nurse unit managers’ knowledge and ability importance of managerial competencies. Methods: The participants were 200 nurse unit managers who worked at general hospitals or tertiary care hospitals. Data were collected from February 1 to June 30, 2021, and analyzed using descriptive statistics, independent t-test, paired t-test, ANOVA, and stepwise multiple regression analysis with IBM SPSS/WIN 26.0. Results: Nurse unit managers perceived the ability of managerial competencies to be less important than knowledge thereof. Overall, nurse unit managers perceived the importance of human and technical competencies as the most important, while the importance of financial managerial competency as the lowest. The significant predictors of knowledge and ability importance of managerial competencies were ‘nursing environment’ and ‘research experience’, and the input variables explained 34% of knowledge importance and 25% of ability importance. Conclusion Nurse administrators should continue to pay attention to the nursing environment, provide nursing unit managers with opportunities to conduct various research and provide related education.

Purpose: The study aimed to identify the factors impacting nurse unit managers’ knowledge and ability importance of managerial competencies. Methods: The participants were 200 nurse unit managers who worked at general hospitals or tertiary care hospitals. Data were collected from February 1 to June 30, 2021, and analyzed using descriptive statistics, independent t-test, paired t-test, ANOVA, and stepwise multiple regression analysis with IBM SPSS/WIN 26.0. Results: Nurse unit managers perceived the ability of managerial competencies to be less important than knowledge thereof. Overall, nurse unit managers perceived the importance of human and technical competencies as the most important, while the importance of financial managerial competency as the lowest. The significant predictors of knowledge and ability importance of managerial competencies were ‘nursing environment’ and ‘research experience’, and the input variables explained 34% of knowledge importance and 25% of ability importance. Conclusion Nurse administrators should continue to pay attention to the nursing environment, provide nursing unit managers with opportunities to conduct various research and provide related education.

Objectives: . This study aimed to compare the oncological outcomes of partial versus superficial or total parotidectomy for superficial T1 or T2 primary parotid cancers and investigate their prognostic factors and recurrence patterns. Methods: . The medical records of 77 patients with T1–2 primary parotid malignancies between May 2003 and March 2022 were retrospectively reviewed. Univariate and multivariate analyses were performed to evaluate the prognostic factors associated with overall survival, disease-free survival, and local and distant recurrence. Results: . The average follow-up duration was 70.2 months (range, 12–202 months). The 5-year overall and disease-free survival rates were 88.7% and 77.1%, respectively. Twenty-two patients underwent partial parotidectomy, and 55 underwent superficial or total parotidectomy. There were no significant differences in the disease recurrence (P=0.320) and mortality rates (P=0.884) of the partial and superficial or total parotidectomy groups. The mean duration of surgery was shorter and the overall complication rates were significantly lower in the partial group than in the superficial or total parotidectomy group (P=0.049). Sixteen cases of recurrence occurred during the study period (20.8%). Univariate analyses showed that high-grade tumors (P=0.006), lymphovascular invasion (P=0.046), and regional lymph node metastasis (P=0.010) were significant risk factors for disease recurrence. Multivariate analysis identified regional lymph node metastasis as an independent prognostic factor for disease recurrence (P=0.027), and lymphovascular invasion as an independent prognostic factor for overall survival (P=0.033). Conclusion . The conservative surgical approach of partial parotidectomy can yield oncological outcomes comparable to those of superficial or total parotidectomy with careful patient selection in T1-2 parotid cancers.

Purpose: To report a case of papillophlebitis treated with an intravitreal bevacizumab injection in an adolescent patient.Case summary: A 15-year-old female with no medical history presented with a 3-day history of blurred vision and a floating sensation. The initial visual acuity (VA) was 0.0 logarithm of minimal angle of resolution (logMAR) in the left eye. A fundus examination revealed a blurry disc margin, peripapillary hemorrhage, and venous engorgement. Optical coherence tomography indicated subretinal fluid (SRF) accumulation. Both color vision and pupillary reactions were normal in bilateral eyes. Blood tests revealed no significant abnormalities. Brain magnetic resonance imaging (MRI) showed mild focal papillitis, but the patient did not report eye movement pain or discomfort. The diagnosis was papillophlebitis; however, high-dose steroid treatment was not initiated due to the absence of a significant decrease in VA. A single injection of intravitreal bevacizumab was administered to address the SRF. At the 9-month follow-up, VA remained at 0.0 logMAR, and the retina demonstrated anatomical stabilization after complete absorption of the SRF without recurrence. Conclusions Papillophlebitis can manifest during adolescence. Treatment of a 15-year-old patient with intravitreal bevacizumab obviated the need for high-dose steroid therapy and produced favorable outcomes, including preservation of VA and anatomical stabilization of the retina.

Purpose: This study was conducted to explore the relationships among new nurses’ meaning of work, organizational commitment, professional self-image, and retention intention through path analysis. Methods: The participants were 872 nurses with less than a year of clinical experience working at general or tertiary hospitals over 500 beds in Korea. The data were collected using structured questionnaires from May 15, 2021 to June 28, 2021, and analysis was conducted using SPSS/WIN 22.0 and AMOS 21.0 programs. Results: Retention intention was explained by meaning of work, organizational commitment, and professional self-image, its explanatory power was 46.5%. The mediating effect of professional self-image was found on the relationship between meaning of work and retention intention. Conclusion To encourage the retention intention among new nurses, an environment where new nurses can set a high value on the meaning of work and sense of accomplishment should be created, and a strategy to improve organizational commitment and professional self-image should be established.

Purpose: To evaluate changes in central macular thickness (CMT) and subfoveal choroidal thickness (SFCT) after phacovitrectomy over a 2-year period in idiopathic epiretinal membrane (ERM) patients. Methods: The records of 52 idiopathic ERM patients (52 eyes) who underwent phacovitrectomy, without recurrence of the condition over a 2-year follow-up period, were reviewed retrospectively. Changes in CMT and SFCT, as measured by optical coherence tomography, were analyzed and compared with those of a normal control group over a 2-year period. Results: The mean preoperative CMT and SFCT were 425.67 ± 84.67 and 257.56 ± 90.13 μm, respectively. Postoperative CMT was reduced significantly to 372.17 ± 45.26 μm at 1 year and 363.15 ± 47.35 μm at 2 years (p < 0.001). SFCT at 1 and 2 years postoperatively was significantly reduced to 238.85 ± 84.85 and 230.31 ± 87.95 μm, respectively (p < 0.001). In the control group, there was no significant change in CMT; however, the SFCT decreased by 11.09 ± 22.36 μm during the 2-year follow-up (p = 0.007). In contrast, in the patient group, CMT and SFCT decreased by 62.52 ± 71.45 and 27.25 ± 41.97 μm, respectively, showing a significant difference from the control group (p < 0.001 and p = 0.043, respectively). Both before surgery and at 1 year postoperatively, the thinner the CMT, the better the best-corrected visual acuity (BCVA) (p = 0.010 and p = 0.018, respectively). A better postoperative BCVA at 2 years was associated with a thinner CMT and better BCVA before surgery (p < 0.001 and p < 0.001, respectively). Conclusions Following a phacovitrectomy procedure, ERM patients showed significant reductions in both the CMT and SFCT at the 2-year follow-up.

Purpose: The purpose of this study was to investigate the influence of e-health literacy in patients with chronic diseases on their healthcare provider-patient communication. Methods: The participants were 184 patients with chronic illnesses admitted to a general hospital. Using a structured-questionnaire, data were collected from December 1 to 31, 2018.Data were analyzed using descriptive statistics, t-test, ANOVA, Scheffé test, Pearson correlation coefficients, and multiple linear regression with IBM SPSS/WIN 22.0. Results: Healthcare provider-patient communication was positively correlated with e-health literacy (r=.87, p <.001). Factors influencing healthcare provider-patient communication were e-health literacy (β=.87, p <.001), subjective health statues (β=.17, p =.011), health concerns (β=-.15, p <.001), number of questions during the hospital treatment (β=.14, p=.003), and education (β=-.14, p =.048). The input variables explained 70.8% of healthcare provider-patient communication. Conclusion The results of this study suggest that healthcare providers should provide reliable online health information to patients and encourage health-oriented attitudes in order to communicate about health information that patients obtained from online.

PURPOSE: To determine the possible effects of chronic exposure of low dose benzalkonium chloride (BAK) on trabecular meshwork cells, and to characterize the pathways involved in the effects. METHODS: Trabecular meshwork cells were treated with 0.0005%, 0.00075%, 0.001%, and 0.0025% BAK for 10 minutes; then, the cells were transferred to a new medium for 24 hours. This process was repeated three times. Cell survival was assessed using the MTT assay to determine the non-apoptotic BAK concentration. Senescence-associated (SA)-β-gal staining was performed to compare quantitatively the cellular senescence of BAK-treated cells with the control group. Cells treated with BAK were analyzed by western blot to determine whether the expressions of cell cycle regulators were affected. RESULTS: Two concentrations (0.0005% and 0.00075%) showed persistent cell viability and were chosen for further experiments. After SA-β-gal staining, cells treated with 0.0005% and 0.00075% BAK showed 28% (± 2.08), 37% (± 2.08) increases in cellular senescence expression, respectively, when compared with control cells (p < 0.05). To identify the molecular pathways involved in cell cycle arrest via BAK, western blot analysis was performed on trabecular meshwork cells, resulting in decreased expressions of cyclin E/CDK2, and increased expressions of the upper stream control molecules, p53 and p21. CONCLUSIONS: Chronic exposure to low dose BAK accelerated cell senescence through cell cycle arrest. Because senescent cells of the trabecular meshwork can inhibit its outflow pathway function and ultimately worsen the glaucomatous process, long-term usage of topical glaucoma medications containing BAK should be conducted with caution.
Aging ; Benzalkonium Compounds ; Blotting, Western ; Cell Aging ; Cell Cycle ; Cell Cycle Checkpoints ; Cell Survival ; Cyclins ; Glaucoma ; Rivers ; Trabecular Meshwork