1. Research progress on management of blood pressure in patients with aortic dissection
Yijia XIE ; Jieting ZHU ; Jienan ZHOU ; Lezhi LI
Chinese Journal of Practical Nursing 2019;35(25):1983-1988
Aortic dissection is a life-threatening cardiovascular condition. The elevated blood pressure plays an important role in the development and the formation of aortic dissection, thus treatment of aortic dissection requires the management of blood pressure control. In this paper, we reported the current situation and summarized the influencing factors of blood pressure management in the treatment of patients with aortic dissection. Suggestions were provided to improve the management of blood pressure control and to support the future research in China.
2.Effect of exercise and nutritional support on the inflammatory parameters among prefrail and frail elderly patients
Chinese Journal of Modern Nursing 2019;25(2):196-199
Objective? To evaluate the effects of exercise and nutritional support on the inflammatory parameters among prefrail and frail elderly patients. Methods? A total of 64 inpatients in the Geriatrics Department of Yancheng Third People's Hospital from April 2016 to October 2017 were selected by convenience sampling method, and randomly divided into control group and intervention group, with 32 cases in each group. The patients in the control group received routine geriatric nursing, while the patients in the intervention group received an adapted physical fitness and nutrition intervention program for 12 weeks. The tumor necrosis factor-α(TNF-α), interleukin 6(IL-6), C-reaction protein (CRP) and total leukocyte count of the patients before and after intervention were compared. Results? There was no statistical significance in the difference of TNF-α and total leukocyte count between the two groups after 12 weeks' intervention (P> 0.05). The IL-6 and CRP of the intervention group were (2.62±1.78) pg/ml and (0.38±0.19) mg/dl respectively, which were both lower than those of the control group, and the differences were statistically significant (P<0.05). Conclusions? In prefrail and frail elderly people, exercise and nutritional support can delay the increase in some inflammatory parameters, like IL-6 and CRP.
3.Correlation among family resilience and negative emotions, exercise compliance in patients receiving chemotherapy after surgery for breast cancer
Jienan ZHU ; Jianyun BIAN ; Jiang Hongxia31Department of Radiotherapy
Chinese Journal of Modern Nursing 2019;25(2):232-235
Objective? To explore the status of family resilience, negative emotions and exercise compliance in patients receiving chemotherapy after surgery for breast cancer and to analyze the correlation between family resilience and negative emotions, exercise compliance. Methods? Patients receiving chemotherapy after surgery for breast cancer in Yancheng Third People's Hospital from March 2016 to March 2018 were selected using convenient sampling. Their family resilience, negative emotions and exercise compliance were evaluated with the family resilience scale, Self-Anxiety Scale (SAS), Self-Depression Scale (SDS) and exercise compliance scale. Spearman analysis was used for correlation analysis. Results? The total score of family resilience in the patients averaged (3.75±0.59); the score of depression totalled (41.52±9.12);the score of depression totaled (46.39±9.87); and the total score of exercise compliance in these patients was (51.32±7.85). Family resilience was negatively correlated with the patients' negative emotions such as anxiety and depression, but positively correlated with exercise compliance (P< 0.05). Conclusions? Low family resilience levels, anxiety and depression, and poor exercise compliance are found in patients receiving chemotherapy after surgery for breast cancer. The patients' family resilience is negatively correlated with negative emotions such as anxiety and depression, but positively correlated with exercise compliance.
4.Risk factors for thyroid nodules among residents of Ningbo City in Zhejiang Province
Xuefei ZHAO ; Jienan ZHANG ; Yawei SUN ; Manhong YAO ; Guoliang ZHU ; Hongjun DONG
Chinese Journal of Endemiology 2015;34(3):213-216
Objective To investigate the prevalence of thyroid nodules among residents of Ningbo City and to explore the risk factors for thyroid nodules.Methods Totally 3 596 residents aged 6-70 were selected by multistage stratified cluster random sampling in Ningbo City,2011.Thyroid ultrasound examination was performed in all participants,while salt iodine and urinary iodine were measured.Possible risk factors for thyroid nodules were analyzed by single factor and multi-factor logistic regression.Results The prevalence rate of thyroid nodules in residents of Ningbo City was 22.66% (815/3 596),with standardized prevalence rate of 17.69%.Female [(odds ratio (OR) =2.06,95% confidence interval (CI) =1.74-2.43],groups of aged 18-(OR =3.42,95% CI =1.22-9.61),aged 40-(OR =13.06,95% CI =4.80-35.51),aged 65-(OR =16.67,95% CI =5.97-46.54) and occasional consumption of seafood habits (less than twice per week,OR =1.23,95% CI =1.02-1.49) were significant associated with thyroid nodules.Conclusions There is no link Letween iodine nutrition and thyroid nodules.It is demonstrated that female and aged ≥ 18 groups have higher risk of thyroid nodules; frequent consumption of seafood seems to be a protective factor.
5.Iodine nutritional status and prevalence of thyroid nodules among residents using non-iodized salt in Ningbo City, Zhejiang Province
Xuefei ZHAO ; Jienan ZHANG ; Yawei SUN ; Manhong YAO ; Guoliang ZHU ; Hongjun DONG
Chinese Journal of Endemiology 2015;34(9):676-679
Objective To investigate the iodine nutritional status,thyroid function and the prevalence of thyroid nodules of residents using non-iodized salt in Ningbo City,Zhejiang Province.Methods In 2011,using typical sampling method,6 villages/communities consumption of non-iodized salt were selected as study fields and residents aged 6-70 were selected as study subjects in Ningbo.Urinary iodine detection,thyroid ultrasound examination and tests of thyroid function [free triiodothyronine (FT3),free thyroxine (FT4),thyroid stimulating hormone (TSH),thyroid peroxidase antibody (TPOAb) and thyroglobulin antibody (TgAb)] were performed in all participants.Urinary iodine concentration (UIC) was determined by arsenic cerium catalytic spectrophotometry,and thyroid function was monitored by chemiluminescence method.Results A total of 1 177 residents agreed to participate in the study,482 were male,and 695 were female (including 2 pregnant women).The participants' mean age was (48.54 ± 13.98) years.The median UIC in all participants was 90.36 μg/L,and the proportions with a UIC < 100μg/L was 56.07% (660/1 177).Furthermore,the median UIC in male was 97.05 μg/L and in female was 83.84 μg/L,there was a significant difference in UICs between male and female (Z =-2.99,P < 0.05).Similarly,significant difference in UICs was observed among age groups (x2 =99.34,P < 0.01).Among the participants,19.88% had thyroid nodules,with standardized prevalence rate of 13.95%.Furthermore,in male,11.83% had thyroid nodules,with standardized prevalence rate of 8.11%,and in female was 25.47%,with standardized prevalence rate of 19.83%,there was a significant difference in the detection rate of thyroid nodules between male and female (x2 =33.25,P < 0.01).Likewise,significant difference in the detection rate of thyroid nodules was observed among age groups (x2=49.65,P< 0.01),and there was a positive and significant correlation between the detection rate of thyroid nodules and increasing age (x2trend =44.22,P < 0.01).Conclusions The residents who using non-iodized salt in Ningbo City are in the status of iodine deficiency.The detection rate of thyroid nodules is higher in female than in male and it has increased with age.
6.Effects of Chinese herbs for replenishing qi and resolving stagnation on hypoxia-inducible factor-1alpha and vascular endothelial growth factor in granulation tissue of skin ulcers in rats with diabetes
Huafa QUE ; Yuanyin ZHU ; Yunfei WANG ; Zhen ZHANG ; Jienan XU ; Jie XING ; Hanjun TANG
Journal of Integrative Medicine 2007;5(2):165-9
OBJECTIVE: To explore the effects of Chinese herbs for replenishing qi and resolving stagnation on hypoxia-inducible factor-1alpha (HIF-1alpha) and vascular endothelial growth factor (VEGF) in granulation tissue of skin ulcers in rats with syndrome of blood stasis and qi deficiency. METHODS: Diabetic rats with back full-thickness skin lesion and syndrome of blood stasis and qi deficiency were divided in to five groups: untreated group, basic fibroblast growth factor (bFGF)-treated group, Yiqi Huayu Recipe (a recipe for replenishing qi and resolving stagnation)-treated group, Yiqi Recipe (a recipe for replenishing qi)-treated group and Huayu Recipe (a recipe for resolving stagnation)-treated group, and another eight normal rats served as normal control group. Immunohistochemical method and image analysis were used to test the expressions of HIF-1alpha and VEGF in granulation tissue of skin ulcers in rats with diabetes. RESULTS: In the untreated group, the expression of HIF-1alpha was significantly increased and the expression of VEGF was significantly decreased as compared with those in the normal control group (P<0.01). The expression of HIF-1alpha was obviously lower (P<0.01) and the expression of VEGF was significantly higher in the four drug treated groups as compared with those in the untreated group. In the Yiqi Huayu Recipe-treated group, the expression of HIF-1alpha was obviously lower than those in the bFGF-treated, Yiqi Recipe-treated and Huayu Recipe-treated groups (P<0.05 or P<0.01), and the expression of VEGF was significantly higher than that in the bFGF-treated group (P<0.01). CONCLUSION: Chinese herbs for replenishing qi and resolving stagnation can promote the wound healing in rats through reducing the expression of HIF-1alpha, accelerating the expression of VEGF in granulation tissue of skin ulcers in rats with diabetes and ameliorating the status of ischemia and hypoxia.

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