Objective: To explore the impact of adverse childhood experiences (ACEs) on health risk behaviors (HRBs) among college students and the mediating role of psychological symptoms, so as to provide a basis for developing intervention strategies. Methods: From March to April 2023, a convenience cluster sample of 1 801 students from 12 universities in Nanning, Liuzhou, Guilin, Wuzhou of Guangxi completed an online survey. A self designed questionnaire, Adverse Childhood Experiences-International Questionnaire (ACE-IQ) and Symptom Checklist-90 (SCL-90) were used for evaluation tools. Binary Logistic regression, structural equation modeling (SEM) and Bootstrap methods were used to analyze the associations and mediating effects. Results: Overall, 71.2% of college students experienced at least one type of ACE, with emotional neglect (40.3%) and emotional abuse ( 25.2 %) having the highest detection rates. The top three HRBs were unhealthy diet (77.8%), physical inactivity (54.1%), and smoking/alcohol use (18.5%). Logistic regression showed that poor family functioning, abuse, and extra familial violence were each associated with an increased risk of smoking/alcohol use ( OR =1.14, 1.11, 1.18) and deliberate self harm ( OR =1.26, 1.19,1.30) (all P <0.05). Experience of abuse increased the risk of high risk sexual behavior and family dysfunction increaded the risk of physical inactivity, respectively ( OR = 1.07 , 1.04, both P <0.05). Mediation analysis revealed that anxiety ( β =0.20) and depression ( β = 0.09 ) partially mediated the pathway from poor family functioning to deliberate self harm; paranoia ( β =0.02) partially mediated the pathway from abuse to high risk sexual behavior; and obsessive-compulsive symptoms ( β =0.26) and depression ( β =0.10) partially mediated the pathway from extra familial violence to deliberate self harm (all P <0.05). Conclusion Psychological symptoms play a mediating role in the association between ACEs and HRBs, and mental health interventions may reduce the risk of HRBs among college students.

Objective:To analyze the effects of different courses of hyperbaric oxygen combined with sertraline on sleep disorders and serum neurologic injury factors in patients after cerebral hemorrhage.Methods:A total of 120 patients with sleep disorders after cerebral hemorrhage were divided into control group ( n=60) and observation group ( n=60) by random number table method. The control group was treated with sertraline only, while the observation group was treated with hyperbaric oxygen on the basis of the treatment in the control group. The sleep quality, clinical efficacy, the levels of serum neuron-specific enolase (NSE), intercellular adhesion molecule-1 (ICAM-1), and tumor necrosis factor-α (TNF-α) before and 10, 20, and 30 d after treatment were compared between the two groups. Results:The scores of Pittsburgh sleep quality index (PSQI) of the observation group were significantly lower than those of the control group at every time point of treatment ( P<0.05); the total sleep time, total deep sleep time, total light sleep time, and rapid eye movement (REM) sleep time of the observation group were significantly longer than those of the control group ( P<0.05); and the sleep latency of the observation group was significantly shorter than that of the control group ( P<0.05). With the prolongation of the treatment course, the PSQI scores of both groups showed decreasing trends ( P<0.05); the total sleep time, total deep sleep time, total light sleep time, and REM sleep time of both groups tended to prolong ( P<0.05); and the sleep latency tended to be shorter ( P<0.05). The total effective rate of the observation group was significantly higher than that of the control group at 10, 20, and 30 d after treatment ( P<0.05). With the prolongation of the treatment course, the total effective rates of the two groups showed increasing trends ( P<0.05); the levels of serum NSE, ICAM-1, and TNF-α in the observation group were significantly lower than those in the control group at every time point of treatment ( P<0.05); and with the prolongation of the treatment course, the above indicators of the two groups showed decreasing trends ( P<0.05). Conclusion:Hyperbaric oxygen therapy combined with sertraline can improve the sleep quality and clinical efficacy of patients after cerebral hemorrhage with sleep disorders.

Objective:To analyze the effects of different courses of hyperbaric oxygen combined with sertraline on sleep disorders and serum neurologic injury factors in patients after cerebral hemorrhage.Methods:A total of 120 patients with sleep disorders after cerebral hemorrhage were divided into control group ( n=60) and observation group ( n=60) by random number table method. The control group was treated with sertraline only, while the observation group was treated with hyperbaric oxygen on the basis of the treatment in the control group. The sleep quality, clinical efficacy, the levels of serum neuron-specific enolase (NSE), intercellular adhesion molecule-1 (ICAM-1), and tumor necrosis factor-α (TNF-α) before and 10, 20, and 30 d after treatment were compared between the two groups. Results:The scores of Pittsburgh sleep quality index (PSQI) of the observation group were significantly lower than those of the control group at every time point of treatment ( P<0.05); the total sleep time, total deep sleep time, total light sleep time, and rapid eye movement (REM) sleep time of the observation group were significantly longer than those of the control group ( P<0.05); and the sleep latency of the observation group was significantly shorter than that of the control group ( P<0.05). With the prolongation of the treatment course, the PSQI scores of both groups showed decreasing trends ( P<0.05); the total sleep time, total deep sleep time, total light sleep time, and REM sleep time of both groups tended to prolong ( P<0.05); and the sleep latency tended to be shorter ( P<0.05). The total effective rate of the observation group was significantly higher than that of the control group at 10, 20, and 30 d after treatment ( P<0.05). With the prolongation of the treatment course, the total effective rates of the two groups showed increasing trends ( P<0.05); the levels of serum NSE, ICAM-1, and TNF-α in the observation group were significantly lower than those in the control group at every time point of treatment ( P<0.05); and with the prolongation of the treatment course, the above indicators of the two groups showed decreasing trends ( P<0.05). Conclusion:Hyperbaric oxygen therapy combined with sertraline can improve the sleep quality and clinical efficacy of patients after cerebral hemorrhage with sleep disorders.