1.Correlation of peripheral blood eosinophils with left ventricular hypertrophy in elderly patients with hypertension
Yinfeng GAO ; Chen ZHANG ; Xiaoqing XI ; Junhong MENG ; Jianting HUO ; Wenli LUO
Chinese Journal of Geriatric Heart Brain and Vessel Diseases 2024;26(12):1396-1400
Objective To investigate the correlation between peripheral blood eosinophil(EOS)and left ventricular hypertrophy(LVH)in elderly patients with hypertension.Methods A retrospec-tive cross-section analysis was conducted on 711 elderly hypertensive patients admitted to our de-partment from January to December 2023.According to their EOS count,they were divided into Group 1(<100×106/L),Group 2[(100-190)× 106/L]and Group 3(>190 × 106/L).The gen-eral clinical data,biochemical indicators,and echocardiographic parameters were compared among the three groups.The correlation between EOS and each indicator was analyzed by using Spearman correlation analysis.Logistic regression analysis was employed to identify the influential factors for hypertension complicated with LVH.Results Smoking history,TG and UA levels,and lymphocyte counts were gradually increased,while HDL-C level was gradually decreased in the three groups with the increment of EOS count(P<0.05,P<0.01).The proportions of usingβ-blockers,calcium channel blockers and statins were gradually increased in the three groups(P<0.05,P<0.01),so were the values of LVM,LVMI,IVST,LVEDD and LVPWT in them(P<0.01).EOS count was positively correlated with the values of LVM,LVMI,IVST,LVEDD and LVPWT,smoking history,TG and UA levels,WBC,lymphocyte and monocyte counts,and ratios of using β-blockers,calcium channel blockers and statins,but negatively with HDL-C level(P<0.05,P<0.01).Binary logistic regression analysis showed that female and HDL-C were protective factors for LVH in hypertensive patients,while age and EOS count were risk factors(OR=0.149,95%CI:0.096-0.230;OR=0.632,95%CI:0.399-0.999;OR=1.034,95%CI:1.007-1.062;OR=1.956,95%CI:1.446-2.645).Conclusion In elderly hypertensive patients with LVH,female and HDL-C are the protective factors,while age and EOS are the risk factors.EOS has a certain correlation with the occurrence of LVH in elderly hypertensive patients.
2.Correlation of peripheral blood eosinophils with left ventricular hypertrophy in elderly patients with hypertension
Yinfeng GAO ; Chen ZHANG ; Xiaoqing XI ; Junhong MENG ; Jianting HUO ; Wenli LUO
Chinese Journal of Geriatric Heart Brain and Vessel Diseases 2024;26(12):1396-1400
Objective To investigate the correlation between peripheral blood eosinophil(EOS)and left ventricular hypertrophy(LVH)in elderly patients with hypertension.Methods A retrospec-tive cross-section analysis was conducted on 711 elderly hypertensive patients admitted to our de-partment from January to December 2023.According to their EOS count,they were divided into Group 1(<100×106/L),Group 2[(100-190)× 106/L]and Group 3(>190 × 106/L).The gen-eral clinical data,biochemical indicators,and echocardiographic parameters were compared among the three groups.The correlation between EOS and each indicator was analyzed by using Spearman correlation analysis.Logistic regression analysis was employed to identify the influential factors for hypertension complicated with LVH.Results Smoking history,TG and UA levels,and lymphocyte counts were gradually increased,while HDL-C level was gradually decreased in the three groups with the increment of EOS count(P<0.05,P<0.01).The proportions of usingβ-blockers,calcium channel blockers and statins were gradually increased in the three groups(P<0.05,P<0.01),so were the values of LVM,LVMI,IVST,LVEDD and LVPWT in them(P<0.01).EOS count was positively correlated with the values of LVM,LVMI,IVST,LVEDD and LVPWT,smoking history,TG and UA levels,WBC,lymphocyte and monocyte counts,and ratios of using β-blockers,calcium channel blockers and statins,but negatively with HDL-C level(P<0.05,P<0.01).Binary logistic regression analysis showed that female and HDL-C were protective factors for LVH in hypertensive patients,while age and EOS count were risk factors(OR=0.149,95%CI:0.096-0.230;OR=0.632,95%CI:0.399-0.999;OR=1.034,95%CI:1.007-1.062;OR=1.956,95%CI:1.446-2.645).Conclusion In elderly hypertensive patients with LVH,female and HDL-C are the protective factors,while age and EOS are the risk factors.EOS has a certain correlation with the occurrence of LVH in elderly hypertensive patients.
3.A case of spontaneous rupture of primary hepatic angiosarcoma.
Qiang ZHANG ; Jianting HUO ; Chunyan WANG
Journal of Central South University(Medical Sciences) 2018;43(11):1276-1280
Primary hepatic angiosarcoma (PHA) is a rare disease with high malignancy. Due to the low incidence, atypical clinical symptoms and signs, it is often misdiagnosed, which results in missing timely treatment, and subsequently influencing the therapeutic effect and prognosis. A case of hepatic angiosarcoma with acute abdominal pain as the first symptom was reported in First Hospital affiliated to Jilin University in Match, 2017. Computed Tomography (CT) examination for this patient was misdiagnosed as a ruptured hemangioma of the liver, and emergency interventional embolization for hemostasis was performed. Blood routine was monitored several times after the operation, which indicated active bleeding. We performed laparotomy and excised the tumor, which was pathologically confirmed as hepatic angiosarcoma. Immunohistochemistry showed that tumor cells expressed CD31 and CD34. After the operation, the family members gave up treatment due to economic limitations and other reasons, and the patient died on the second day after discharge.
Embolization, Therapeutic
;
Fatal Outcome
;
Hemangiosarcoma
;
surgery
;
Humans
;
Liver Neoplasms
;
surgery
;
Rupture, Spontaneous
;
surgery

Result Analysis
Print
Save
E-mail