1.Application of digital health technologies in upper limb motor function rehabilitation after stroke from 2015 to 2025: a bibliometric analysis
Rui LIU ; Zhenmei GAO ; Xingyu ZHOU ; Qi ZHANG ; Jianlin WU
Chinese Journal of Rehabilitation Theory and Practice 2026;32(5):534-549
ObjectiveTo analyze the current research status, hotspots and future trends of the application of digital health technology (DHT) in the rehabilitation of upper limb motor function after stroke. MethodsRelevant literature on the application of DHT in upper limb motor rehabilitation for stroke patients published between January, 2015 and December, 2025 was retrieved from Web of Science Core Collection, CNKI and Wanfang database. CiteSpace 6.4.R1 was used for visualized bibliometric analysis. ResultsA total of 1 295 publications were included, comprising 454 in Chinese and 841 in English. The annual number of publications generally showed an upward trend. China ranked first in publication output in English literature. The institutions with the highest numbers of publications were Huashan Hospital Affiliated to Fudan University and Swiss Federal Institute of Technology in Zurich. Both Chinese and English keywords formed ten clustering groups. Chinese clusters mainly involved occupational therapy, neural mechanisms and home-based rehabilitation, whereas English clusters focused on virtual reality, brain-computer interfaces and machine learning. High-frequency keywords included virtual reality, brain-computer interface, machine learning and deep learning. Chinese keywords with a strong burst included rehabilitation training, while deep learning showed a strong burst in English keywords. Stroke was the most frequently cited journal. Highly cited journals covered multiple disciplines, including rehabilitation medicine, neuroscience and computer science, reflecting the interdisciplinary characteristics of this field. ConclusionResearches on DHT for upper limb motor function rehabilitation in stroke are increasing annually, focusing on core interaction technologies, neural mechanism and artificial intelligence. Future research trends may include inter-disciplinary integration of artificial intelligence with core rehabilitation technologies, neuroimaging-guided targeted interventions, optimisation of home-based rehabilitation systems, and development of multidimensional quantitative assessment models.
2.Prevalence and risk factors of insomnia in Air Force servicemen deployed to highland areas
Jin WANG ; Jiajia LIU ; Xuemin LIAO ; Jin ZHOU ; Huai JIANG ; Dan HE ; Jianlin QI
Chinese Mental Health Journal 2025;39(11):962-969
Objective:To explore the prevalence and risk factors of insomnia in Chinese Air Force servicemen deployed to highland areas.Methods:A total of 718 Air Force servicemen deployed to Qinghai-Tibetan plateau were recruited at May 2024.Sleep quality was assessed with the Pittsburgh Sleep Quality Index.Social-demograph-ic,military service,and psychological characteristics were measured with a self-administered general question-naire.Bivariable and multivariable logistic regressions were performed to identify independent risk factors.Missing data were handled by the multiple imputation.Results:The average sleep duration was(6.9±1.2)h and the aver-age PSQI score was(5.9±4.1).Totally 53.8%of participants experienced clinically significant insomnia.The multivariable analysis revealed that age≥35(aOR=4.07,95%CI=1.11-17.76),stressful event(aOR=3.27,95%CI=2.00-5.49),dysfunctional sleep beliefs and attitudes(aOR=2.59,95%CI=1.75-3.85),and caffeine product usage(aOR=1.69,95%CI=1.17-2.43)were risk factors for insomnia,while Tibetan-indigenous ethnic(aOR=0.44,95%CI=0.20-0.91),higher perceived social support(aOR=0.96,95%CI=0.96-0.99),and positive coping style(aOR=0.96,95%CI=0.93-0.99)were protective factors.Conclusion:Air force service-men deployed to highland areas have sufficient sleep time,but reduced sleep quality.Age,exposed to stress event during deployment,dysfunctional sleep beliefs and attitudes,and caffeine product usage are risk factors for insomni-a,while Tibetan-indigenous ethnic,higher perceived social support and positive coping style act as protective fac-tors.
3.Prevalence and risk factors of insomnia in Air Force servicemen deployed to highland areas
Jin WANG ; Jiajia LIU ; Xuemin LIAO ; Jin ZHOU ; Huai JIANG ; Dan HE ; Jianlin QI
Chinese Mental Health Journal 2025;39(11):962-969
Objective:To explore the prevalence and risk factors of insomnia in Chinese Air Force servicemen deployed to highland areas.Methods:A total of 718 Air Force servicemen deployed to Qinghai-Tibetan plateau were recruited at May 2024.Sleep quality was assessed with the Pittsburgh Sleep Quality Index.Social-demograph-ic,military service,and psychological characteristics were measured with a self-administered general question-naire.Bivariable and multivariable logistic regressions were performed to identify independent risk factors.Missing data were handled by the multiple imputation.Results:The average sleep duration was(6.9±1.2)h and the aver-age PSQI score was(5.9±4.1).Totally 53.8%of participants experienced clinically significant insomnia.The multivariable analysis revealed that age≥35(aOR=4.07,95%CI=1.11-17.76),stressful event(aOR=3.27,95%CI=2.00-5.49),dysfunctional sleep beliefs and attitudes(aOR=2.59,95%CI=1.75-3.85),and caffeine product usage(aOR=1.69,95%CI=1.17-2.43)were risk factors for insomnia,while Tibetan-indigenous ethnic(aOR=0.44,95%CI=0.20-0.91),higher perceived social support(aOR=0.96,95%CI=0.96-0.99),and positive coping style(aOR=0.96,95%CI=0.93-0.99)were protective factors.Conclusion:Air force service-men deployed to highland areas have sufficient sleep time,but reduced sleep quality.Age,exposed to stress event during deployment,dysfunctional sleep beliefs and attitudes,and caffeine product usage are risk factors for insomni-a,while Tibetan-indigenous ethnic,higher perceived social support and positive coping style act as protective fac-tors.
4.Effectiveness of self-assisted couple communication program on prenatal depression symptoms and marital quality
Jin WANG ; Yingzhi RIHUO ; Jiajia LIU ; Ning SONG ; Gaohua LIU ; Lihua LIU ; Jianlin QI
Chinese Mental Health Journal 2023;37(12):1045-1051
Objective:To explore the effectiveness of self-assisted couple communication program(SACCP)onprenatal depression and marital quality in pregnant women.Methods:Totally 90 pregnant women receiving ante-natal checkup in Air Force Medical Center with the Edinburgh Postnatal Depression Scale(EPDS)scores of ≥10 were voluntarily recruited and randomly allocated in routine caring and SACCP groups.Thirty-nine pregnant women in SACCP group and 37 pregnant women in routine caring group ultimately completed the study.In addition to rou-tine caring,the SACCP group completed a 10-week self-assisted family communication program once a week.The EPDS and Olson Marital Quality Questionnaires(ENRICH)were used as outcomes,and covariance and independ-ent t-teat were adopted to evaluate intervention effectiveness.Statistical analysis was conducted using the full analy-sis set and the per protocol set respectively.Results:Totally 76(84.4%)pregnant women received allocation and end-point revaluation.Covariance analysis revealed that EPDS adjusted means were higher in the SACCP group than in the routine caring group(P<0.05)in both sets.T-test showed that marital satisfaction and couple communica-tion scores were higher in the SACCP group than in the routine caring group(Ps<0.01)in the full analysis set.Conclusion:The self-assisted couple communication program(SACCP)could effectively alleviate clinical symptoms of prenatal depression of pregnant women and improve marital quality.
5.Investigation on qualification criteria of age, flying hours and personality characteristics among test pilots
Jin WANG ; Jiajia LIU ; Chuan YU ; Jing WU ; Jianlin QI
Chinese Journal of Aerospace Medicine 2022;33(2):77-81
Objective:To investigate the qualification criteria of age, flying hours and personality characteristics among test pilots, and to provide theoretical foundation on development of test pilots qualification strategies.Methods:Thirty-six test pilots were randomly selected to complete Cattell's 16 Personality Factor (16PF) and Minnesota Multiphasic Personality Inventory(MMPI) assessments. They were divided into 30-39 years group and 40-49 years group. The 16PF and MMPI scores were compared between different age groups. Among which, 30 test pilots, who were experienced test flight for over 2 500 h, were selected for semi-structure interview to sample their opinion on the requirements of age and flying hours of being a test pilot.Results:The statistic of interview showed that the age and flying hours requirements of fighter test pilots would be 30-35 years old and >1 000 h respectively, while 30-35 years old and unrestricted flying hours for the test pilots of bomber and transporter. The selection should meet the physical requirements of high-performance fighter pilots for those 2 kinds of test pilot. In MMPI assessments, correction scale scores of the test pilots in 30-39 years group were significantly lower than those in 40-49 years group ( U=97.50, P=0.040), but their schizophrenia scale scores were significantly higher than those in 40-49 years group ( U=95.50, P=0.035). There was no significant difference between groups in other personality scales (all P>0.05). Conclusions:The test pilots for different aircraft types ask for different flying hours requirements. Even the fighter and bomber/transporter ask for test pilot′s different flying hours requirements, but due to the insignificance on personality characteristics between different age groups, it would be necessary to investigate further on the selection criteria for different age segments.
6.Investigation on qualification criteria of age, flying hours and personality characteristics among test pilots
Jin WANG ; Jiajia LIU ; Chuan YU ; Jing WU ; Jianlin QI
Chinese Journal of Aerospace Medicine 2022;33(2):77-81
Objective:To investigate the qualification criteria of age, flying hours and personality characteristics among test pilots, and to provide theoretical foundation on development of test pilots qualification strategies.Methods:Thirty-six test pilots were randomly selected to complete Cattell's 16 Personality Factor (16PF) and Minnesota Multiphasic Personality Inventory(MMPI) assessments. They were divided into 30-39 years group and 40-49 years group. The 16PF and MMPI scores were compared between different age groups. Among which, 30 test pilots, who were experienced test flight for over 2 500 h, were selected for semi-structure interview to sample their opinion on the requirements of age and flying hours of being a test pilot.Results:The statistic of interview showed that the age and flying hours requirements of fighter test pilots would be 30-35 years old and >1 000 h respectively, while 30-35 years old and unrestricted flying hours for the test pilots of bomber and transporter. The selection should meet the physical requirements of high-performance fighter pilots for those 2 kinds of test pilot. In MMPI assessments, correction scale scores of the test pilots in 30-39 years group were significantly lower than those in 40-49 years group ( U=97.50, P=0.040), but their schizophrenia scale scores were significantly higher than those in 40-49 years group ( U=95.50, P=0.035). There was no significant difference between groups in other personality scales (all P>0.05). Conclusions:The test pilots for different aircraft types ask for different flying hours requirements. Even the fighter and bomber/transporter ask for test pilot′s different flying hours requirements, but due to the insignificance on personality characteristics between different age groups, it would be necessary to investigate further on the selection criteria for different age segments.
7.Predictive value of cerebroplacental ratio for perinatal outcomes of induction of labor in prolonged pregnancy
Jianlin ZHAO ; E GONG ; Haijun SHI ; Lan ZHANG ; Xing WANG ; Hongli LIU ; Jie GAN ; Chiying CAO ; Shuai HUANG ; Junnan LI ; Hongbo QI
Chinese Journal of Perinatal Medicine 2021;24(3):209-213
Objective:To investigate the predictive value of cerebroplacental ratio (CPR) for adverse perinatal outcomes of induction of labor in prolonged pregnancy.Methods:This retrospective study recruited 315 singleton pregnant women who had induced labor due to prolonged pregnancy (≥41 gestational weeks) in the First Affiliated Hospital of Chongqing Medical University from January 1, 2019 to April 30, 2020. Based on the occurrence of adverse perinatal outcomes (emergency delivery due to persistent abnormal fetal heart rate monitoring, umbilical artery blood pH at birth <7.2, 5 min Apgar scores<7, transferring to neonatal intensive care unit after birth, chorioamnionitis and vaginal delivery converted to cesarean section), they were divided into two groups: case group ( n=76) and normal group ( n=239). Clinical features and umbilical artery blood flow, middle cerebral artery (MCA) flow and CPR measured in the last ultrasound scan before induction were compared between the two groups using student's t-test, Mann-Whitney U test and Chi-square test. Receiver operating characteristic (ROC) curve was used to analyze the predictive values of umbilical artery blood flow, MCA flow and CPR for the adverse perinatal outcomes. Multivariate logistic regression analysis was used to screen the meaningful predictors. Results:Compared with the normal group, the umbilical artery pulsatility index (PI) (0.9±0.1 vs 0.8±0.1, t=-5.458, P<0.001) and the percentage of abnormal CPR (<1.0) increased significantly [21.1%(16/76) vs 6.3%(15/239), χ2=14.190, P<0.001] in the case group, while the MCA-PI and CPR decreased significantly (1.1±0.2 vs 1.3±0.3, t=5.658, P<0.001; 1.2±0.3 vs 1.6±0.5, t=8.940, P<0.001). The areas under the ROC curves of umbilical artery PI, MCA-PI and CPR for predicting adverse perinatal outcomes were 0.71, 0.71 and 0.77, respectively. CPR had the highest sensitivity (0.74) compared with umbilical artery PI (0.68) and MCA-PI (0.71), but the specificity of them were similar (0.67, 0.66 and 0.66). Multivariate logistic regression analysis showed that only CPR was the independent risk factor for adverse perinatal outcomes ( OR=0.028, 95% CI: 0.010-0.080, P<0.001). Conclusions:As an indicator for early prediction of adverse perinatal outcomes of induction of labor in prolonged pregnancy, CPR was more sensitive but less specific.
8.Cognitive processing characteristics of depression in emotional Stroop and memory recognition
Jing WU ; Jin WANG ; Jiajia LIU ; Chuan YU ; Gaohua LIU ; Jianlin QI
Chinese Journal of Behavioral Medicine and Brain Science 2021;30(11):992-996
Objective:To explore the cognitive processing characteristics of semantic emotion Stroop and memory recognition in pilots with depression, and to systematically reveal the cognitive processing characteristics of attention and memory.Methods:The semantic emotional Stroop task and memory recognition test were performed in 36 depressed pilots and 36 healthy pilots.The results of attention and memory in cognitive processing were analyzed by repeated measurement analysis of variance using SPSS 18.0 software.Results:In the semantic emotion Stroop, the response time of the depression group was longer than that of the control group ( F(1, 70)=7.03, P=0.008), and the response time of the depression group(579.55±141.62)ms ) was longer than that of the neutral words (565.66±132.60)ms, P=0.003) and positive words (563.09±138.88)ms, P<0.01). In memory recognition, the accuracy of response to emotion words in the depressed group was higher than that in the control group ( F(1, 70)=23.15, P<0.01). The accuracy of response to negative words was higher in the depressed group than that to positive words ((0.50±0.32) vs (0.32±0.21), P=0.006) and neutral words ((0.50±0.32) vs (0.33±0.23), P=0.007). The depression group showed a conservative bias towards negative words ((1.46±0.40), P<0.01), and negative words compared with neutral words ((0.63±0.24), P<0.01) and positive words ((0.57±0.27), P<0.01) were cautious and conservative. Conclusion:Patients with depression have attention bias toward the negative information in semantic information processing, and negative memory bias in memory recognition.
9.Observation on the effect of Jinqiao-Reduqing granule for hte children with herpetic angina fever
International Journal of Traditional Chinese Medicine 2019;41(8):817-820
Objective To evaluate the effect of Jinqiao-Reduqing granule in the treatment of children with herpes angina fever.Methods A total of 90 children with herpes angina were randomly divided into two groups,with 45 cases in each group.Both groups received the symptom-supported treatment.On this basis,the control group took ribavirin granules,while the observation group took Jinqiao-Reduqing granule.Both groups were treated for 4 days.The symptoms and signs were scored before and after treatment.The fever abatement time,herpes subsidence time,salivation disappearance time and appetite recovery time were observed and recorded.The serum levels of IL-2,IL-6,IL-10 and TNF-α were detected by ELISA,and peripheral blood levels of CD4+,CD8+,CD4+/CD8+ were detected by flow cytometry.Results After treatment,the scores of symptoms and signs in the observation group were significantly lower than those in the control group (3.02 ± 2.89 vs.6.88 ± 2.31;t=6.999,P<0.01).The time of fever abatement (16.8 ± 3.2 h vs.29.9 ± 4.4 h,t=16.202),herpes subsidence (72.3 ± 5.4 h vs.96.7 ± 6.2 h,t=19.765),salivation disappearance (26.4 ± 2.0 h vs.46.3 ± 3.6 h,t=32.479) and appetite recovery (19.6 ± 4.2 h vs.39.7 ± 4.9 h,t=20.907) were significantly earlier than those in the control group (P<0.01).After treatment,the serum levels of IL-2,IL-6,IL-10 and TNF-α in the observation group were lower than those in the control group (t were 4.974,4.410,6.447 and 4.767,respectively,all Ps<0.01);CD4+ levels and CD4+/CD8+ were significantly higher than those in the control group (t were 4.033,6.860,all Ps< 0.01),and CD8+ levels was significantly lower than those in the control group (t=4.928,P<0.01).Conclusions The Jinqiao-Reduqing granule can shorten the time of symptoms subsidence,reduce the level of inflammatory cytokines and improve the immunity of children with herpes angina fever.
10.Correlation between preoperative serum alpha-fetoprotein (AFP) level and early recurrence of patients with hepatocellular carcinoma after partial hepatectomy
Zhen YANG ; Jianlin WANG ; Runze SHANG ; Qi LIU ; Kefeng DOU
Chinese Journal of Hepatobiliary Surgery 2018;24(3):179-183
Objective To study the relationship between preoperative serum a-fetoprotein (AFP) level and early recurrence of patients with hepatocellular carcinoma (HCC) after partial hepatectomy.Methods 267 patients with hepatocellular carcinoma who underwent partial hepatectomy in Xijing Hospital,the Fourth Military Medical University from January 2011 to November 2015 were retrospectively studied.The patients were divided into the AFP-negative group (AFP ≤20 μg/L) and the AFP-positive group (AFP > 20 μg/L) according to the preoperative serum AFP levels.The risk factors of early recurrence of HCC in patients after partial hepatectomy were studied by multivariate regression analysis.The recurrence-free survival rates during 24 months after surgery between the AFP-negative group and the AFP-positive group were compared.Results In 267 patients,97 patients had low or negative AFP levels (AFP≤20 μg/L) and 170 patients had high or positive AFP levels (AFP > 20 μg/L).Patients in the AFP-positive group had significantly more well differentiated HCC on tumor histology when compared with patients in the AFP-negative group (x2 =17.050,P < 0.05).The proportion of patients with liver cirrhosis in the AFP-positive group was significantly higher than that of the AFP-negative group (x2 =4.374,P < 0.05).On the other hand,the numbers of patients with adjacent tissue invasion (x2 =4.374,P < 0.05) and early HCC recurrence (x2 =7.595,P < 0.05) in the AFP-positive group were significantly less than those of the AFP-negative group.Survival analysis showed that the recurrence-free survival rates in the AFP-positive and negative groups were 35.3%,52.6%,respectively.The results on univariate analysis showed that portal vein tumor thrombus,HBsAg positivity,tumor number,tumor diameter,tumor tissue differentiation,preoperative serum AFP level and adjacent tissue invasion were significantly associated with early recurrence of liver cancer (P < 0.05).Cox multivariate regression analysis revealed that serum AFP positivity (HR =1.605,P < 0.05),portal vein tumor thrombosis (HR =3.936,P < 0.05),HBsAg positivity (HR =1.621,P <0.05),tumor diameter (HR =1.977,P < 0.05) and tumor number (HR =1.991,P < 0.05) were significantly correlated with early recurrence of liver cancer after partial hepatectomy.Conclusion The preoperative serum AFP level had an important predictive value for early recurrence of primary hepatocellular carcinoma in patients after partial hepatectomy.

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