Eosinophilic esophagitis (EoE) is a chronic inflammatory disease driven by immune mechanisms, characterized by abnormal eosinophilic infiltration of the esophageal epithelium. EoE′s pathogenesis is closely associated with food allergens, and clinical manifestations primarily include dysphagia, food impaction, and children patients may also have growth restriction. The European Society for Paediatric Gastroenterology, Hepatology, and Nutrition first published guidelines for the management of pediatric EoE in 2014. With increasing understanding of the disease mechanisms and treatment responses, the 2024 guidelines have comprehensively updated the diagnostic and therapeutic strategies.This paper provides a systematic interpretation of the 2024 guidelines, focusing on the revised diagnostic criteria, optimization of dietary therapy, and improved management strategies for esophageal strictures. Furthermore, a comparison of the 2014 and 2024 guidelines highlights significant advancements in EoE management over the past decade and their implications for clinical practice.

Objective To evaluate the efficacy of the venous thromboembolism(VTE)digital risk prevention and control platform based on whole-process closed-loop management for the quality management of VTE in Peking University Shenzhen Hospital.Methods The data of 360 718 hospitalized patients from 2021 to 2024 were collected to analyze the rate of VTE risk assessment,the proportion of VTE intermediate and high-risk patients,the rate of VTE prophylaxis implementation(physical/pharmacological),and the VTE outcome indexes,and the differences between groups were verified using the Cochran-Armitage χ2 trend test.Results The VTE initial risk assessment rate,the implementation rate of VTE physical prophylaxis,and the rate of VTE pharmacological prophylaxis all showed an upward trend;the incidence rate of hospital correlated VTE,and the incidence rate of VTE in hospitalized surgical patients all showed a downward trend.Conclusion The establishment of the VTE digital risk prevention and control intelligent platform can effectively improve the level of standardized prevention and treatment of in-hospital VTE and the efficacy of quality management,and provide a digital management paradigm for the implementation of the national healthcare quality and safety improvement goals and the monitoring indicators of surgical quality and safety improvement actions.

Objective To evaluate the efficacy of the venous thromboembolism(VTE)digital risk prevention and control platform based on whole-process closed-loop management for the quality management of VTE in Peking University Shenzhen Hospital.Methods The data of 360 718 hospitalized patients from 2021 to 2024 were collected to analyze the rate of VTE risk assessment,the proportion of VTE intermediate and high-risk patients,the rate of VTE prophylaxis implementation(physical/pharmacological),and the VTE outcome indexes,and the differences between groups were verified using the Cochran-Armitage χ2 trend test.Results The VTE initial risk assessment rate,the implementation rate of VTE physical prophylaxis,and the rate of VTE pharmacological prophylaxis all showed an upward trend;the incidence rate of hospital correlated VTE,and the incidence rate of VTE in hospitalized surgical patients all showed a downward trend.Conclusion The establishment of the VTE digital risk prevention and control intelligent platform can effectively improve the level of standardized prevention and treatment of in-hospital VTE and the efficacy of quality management,and provide a digital management paradigm for the implementation of the national healthcare quality and safety improvement goals and the monitoring indicators of surgical quality and safety improvement actions.

Eosinophilic esophagitis (EoE) is a chronic inflammatory disease driven by immune mechanisms, characterized by abnormal eosinophilic infiltration of the esophageal epithelium. EoE′s pathogenesis is closely associated with food allergens, and clinical manifestations primarily include dysphagia, food impaction, and children patients may also have growth restriction. The European Society for Paediatric Gastroenterology, Hepatology, and Nutrition first published guidelines for the management of pediatric EoE in 2014. With increasing understanding of the disease mechanisms and treatment responses, the 2024 guidelines have comprehensively updated the diagnostic and therapeutic strategies.This paper provides a systematic interpretation of the 2024 guidelines, focusing on the revised diagnostic criteria, optimization of dietary therapy, and improved management strategies for esophageal strictures. Furthermore, a comparison of the 2014 and 2024 guidelines highlights significant advancements in EoE management over the past decade and their implications for clinical practice.

To interpret the clinical practice guidelines for pediatric and eosinophilic gastrointestinal disorders beyond eosinophilic esophagitis (non-EoE EGID), jointly developed by the European Society for Paediatric Gastroenterology, Hepatology and Nutrition and the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition. The guidelines provide new standards for the diagnosis and treatment of non-EoE EGID. They include detailed explanations on disease classification, diagnostic and therapeutic challenges, guideline development methodology, epidemiology, etiological mechanisms, symptoms, endoscopic and imaging examinations, other tests, differential diagnosis, and treatment strategies. The paper explores the importance of comprehensive assessment in children with non-EoE EGID. Improvement suggestions are proposed, such as developing symptom assessment tools, conducting quality of life impact studies, standardizing eosinophil density reporting, refining diagnostic criteria, and formulating specific treatment guidelines. These measures aim to enhance the diagnostic and therapeutic accuracy for non-EoE EGID and improve the clinical management of affected children.

Objective To identify the current research hotspots of global health training, and construct a global health talent training evaluation index system. Methods Publications pertaining to global health talent training evaluation were retrieved in China National Knowledge Infrastructure, Wanfang Database, and Web of Science Core Collection from 2003 to 2022, and keywords were extracted from eligible publications for co-occurrence and cluster analyses using the CiteSpace software. Based on keywords clustering results, a global health talent training evaluation index system was constructed using a context, input, process, and product (CIPP) evaluation model as a theoretical framework. Results A total of 692 Chinese publications and 1 264 English publications were included. Keyword co-occurrence and cluster analyses yielded 10 Chinese and 10 English keyword clusters, and the 10 Chinese keyword clusters included analytic hierarchy process, health diplomacy, personnel structure, crossdiscipline, educational assessment, global health discipline development, training needs, curriculum program, quality evaluation and logistics support, while the English keyword clusters included evidence-based practice, capacity building, global health, quality of life, machine learning, leadership, sub-Saharan Africa, health equity, global health security and global health diplomacy. Based on keyword clustering, a global health talent training evaluation index system was constructed with CIPP as the theoretical framework, which contained 4 primary indicators, 15 secondary indicators and 59 tertiary indicators, and the primary indicators included 4 dimensions of context evaluation, input evaluation, process evaluation and product evaluation. Conclusions A global health talent training evaluation index system has been constructed, which provides an effective evaluation tool and quantitative evidence for future global health talent training.

Currently, there is a lack of localized guidelines or consensus on the management of Ebstein anomaly (EA) in China, particularly concerning the treatment of neonates and infants. The 2024 Expert Consensus issued by the American Association for Thoracic Surgery provides detailed guidance on the clinical management of EA, covering key aspects such as the timing of surgical interventions, selection of surgical techniques, and postoperative management. The interpretation of this consensus is of great significance for thoracic surgeons in China to understand the latest international academic developments and can serve as a valuable reference for clinical practice. The consensus outlines the latest surgical techniques adopted internationally, including the Starnes procedure, biventricular repair, and 1.5 ventricle repair, and provides an in-depth analysis of the optimal timing and strategies for interventions in different cases. This offers a theoretical foundation and technical reference for advancing the field in China, contributing to the standardization and regulation of EA treatment.

To interpret the clinical practice guidelines for pediatric and eosinophilic gastrointestinal disorders beyond eosinophilic esophagitis(non-EoE EGID),jointly developed by the European Society for Paediatric Gastroenterology,Hepatology and Nutrition and the North American Society for Pediatric Gastroenterology,Hepatology and Nutrition.The guidelines provide new standards for the diagnosis and treatment of non-EoE EGID.They include detailed explanations on disease classification,diagnostic and therapeutic challenges,guideline development methodology,epidemiology,etiological mechanisms,symptoms,endoscopic and imaging examinations,other tests,differential diagnosis,and treatment strategies.The paper explores the importance of comprehensive assessment in children with non-EoE EGID.Improvement suggestions are proposed,such as developing symptom assessment tools,conducting quality of life impact studies,standardizing eosinophil density reporting,refining diagnostic criteria,and formulating specific treatment guidelines.These measures aim to enhance the diagnostic and therapeutic accuracy for non-EoE EGID and improve the clinical management of affected children.

To interpret the clinical practice guidelines for pediatric and eosinophilic gastrointestinal disorders beyond eosinophilic esophagitis(non-EoE EGID),jointly developed by the European Society for Paediatric Gastroenterology,Hepatology and Nutrition and the North American Society for Pediatric Gastroenterology,Hepatology and Nutrition.The guidelines provide new standards for the diagnosis and treatment of non-EoE EGID.They include detailed explanations on disease classification,diagnostic and therapeutic challenges,guideline development methodology,epidemiology,etiological mechanisms,symptoms,endoscopic and imaging examinations,other tests,differential diagnosis,and treatment strategies.The paper explores the importance of comprehensive assessment in children with non-EoE EGID.Improvement suggestions are proposed,such as developing symptom assessment tools,conducting quality of life impact studies,standardizing eosinophil density reporting,refining diagnostic criteria,and formulating specific treatment guidelines.These measures aim to enhance the diagnostic and therapeutic accuracy for non-EoE EGID and improve the clinical management of affected children.

Currently, there is a lack of localized guidelines or consensus on the management of Ebstein anomaly (EA) in China, particularly concerning the treatment of neonates and infants. The 2024 Expert Consensus issued by the American Association for Thoracic Surgery provides detailed guidance on the clinical management of EA, covering key aspects such as the timing of surgical interventions, selection of surgical techniques, and postoperative management. The interpretation of this consensus is of great significance for thoracic surgeons in China to understand the latest international academic developments and can serve as a valuable reference for clinical practice. The consensus outlines the latest surgical techniques adopted internationally, including the Starnes procedure, biventricular repair, and 1.5 ventricle repair, and provides an in-depth analysis of the optimal timing and strategies for interventions in different cases. This offers a theoretical foundation and technical reference for advancing the field in China, contributing to the standardization and regulation of EA treatment.