1.Overview of Physical Biological Research on the Activation of Acupoint Effects by Acupuncture
Junyi LI ; Shiwei TU ; Yangyang LIU ; Baomin DOU ; Zezhi FAN ; Jiangjiang FU ; Jiangqi ZHOU ; Kaiyuan DENG ; Yanwei LI ; Yi GUO
Journal of Traditional Chinese Medicine 2026;67(10):1130-1136
By reviewing the physical biological research on the activation of acupoint effects by acupuncture， this paper explains the activation mechanism from the perspective of the generation and transmission of mechanical signals caused by acupuncture， and reveals the physical-chemical coupling processes in the acupoint microenvironment. Future research should focus on locally mechanosensitive cells， further exploring how acupuncture mechanical signals trigger dynamic changes in cells and molecules in the acupoints， and the physical-chemical information transduction mechanism， which will provide scientific evidence for the acupoint activation during acupuncture. Related studies will contribute to a deeper understanding of the scientific principles behind acupuncture and promote its clinical application and development.
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