Objective? To explore the effects of enhanced recovery after surgery (ERAS) in perioperative care for intracerebral aneurysm. Methods? Totally 353 patients with intracerebral anterior circulation aneurysm who were treated with the craniotany clipping technique in a ClassⅢ Grade A hospital from November 2016 to November 2018 were selected. A total of 291 patients admitted from November 2016 to December 2017 were included in the control group which received conventional perioperative nursing care, while 62 patients admitted between January and November 2018 were included into the ERAS group which received ERAS nursing care. The length of hospital stay, Glasgow Outcome Scale (GOS) and incidence of complications were compared between the two groups. Results? The length of hospital stay and the GOS score of the ERAS group was (14.426±4.264) d and (4.019±0.533), respectively, while those of the control group were (15.931±6.814) d and (4.676±0.705), respectively (t'=2.117, 7.937; P＜0.05). There was no statistical difference in the incidence rate of central nervous system infection (CNSI) and pulmonary infection between the two groups (P＞0.05). However, the incidence rate of lower limb vein thrombosis of the ERAS group was 4.61% (1/62), while that of the control group was 9.32% (27/219) (χ2=6.185,P＜ 0.05). Conclusions? The ERAS perioperative care for intracerebral aneurysm helps to reduce the length of hospital stay, improve GOS scores and curtail the incidence rate of lower limb vein thrombosis in these patients.