Objective:To investigate the safety and clinical effect of testis-sparing microsurgery(TSMS)in the treatment of benign testis tumor(BTT).Methods:We retrospectively analyzed the clinical data on 16 cases of BTT treated in the Department of Andrology of the Affiliated Hospital of Qingdao University from October 2020 to February 2023.The median age of the patients was 23 years.All the tumors were unilateral,7 in the left and 9 in the right side,with a median diameter of 1.85 cm(1.0-3.5 cm).The patients all underwent color Doppler flow imaging(CDFI),MRI,semen analysis and examination of serum T,alpha-fetoprotein(AFP),human chorionic gonadotropin(HCG)and lactate dehydrogenase(LDH),followed by TSMS.The boundaries between the tumors and normal testis tissue were accurately identified under the microscope,and the tumors and the adjacent normal testis tissue 2 mm from their margins were excised completely.Bipolar coagulation forceps were used for wound hemostasis to maximally preserve the normal testis tissue.The resected specimens were subjected to fast frozen pathology intraoperatively,and the patients were followed up for 14-40 months by regular scrotal CDFI,MRI and examinations of serum T and semen parameters.Results:The levels of serum T,AFP,HCG and LDH and semen parameters were all within the normal range preoperatively.TSMS were successfully completed in all the cases,and all were pathologically confirmed as BTT according to the latest edition of WHO Classification of Tumors:Urinary and Male Genital Tumors.CDFI showed normal blood supply within the testis tissue at 1 month after surgery.No signs of intra-testicu-lar tumor residue,recurrence or metastasis,nor significant changes in the levels of serum T,AFP,HCG or LDH or semen parameters were observed during the follow-up as compared with the baseline.Natural conception was achieved in 2 cases at 16 and 18 months re-spectively after surgery.Conclusion:BTT can be differentially diagnosed by CDFI and MRI before surgery and confirmed by histo-pathology.TSMS can achieve complete excision of the tumor,maximal sparing of the normal testis tissue and thereby effective preserva-tion of male fertility.

Patients with congenital unilateral absence of the vas deferens (CUAVD) manifest diverse symptoms from normospermia to azoospermia. Treatment for CUAVD patients with obstructive azoospermia (OA) is complicated, and there is a lack of relevant reports. In this study, we describe the clinical features and evaluate the treatments and outcomes of CUAVD patients with OA. From December 2015 to December 2020, 33 patients were diagnosed as CUAVD with OA in Shanghai General Hospital (Shanghai, China). Patient information, ultrasound findings, semen analysis, hormone profiles, and treatment information were collected, and the clinical outcomes were evaluated. Of 33 patients, 29 patients were retrospectively analyzed. Vasoepididymostomy (VE) or cross VE was performed in 12 patients, the patency rate was 41.7% (5/12), and natural pregnancy was achieved in one of the patients. The other 17 patients underwent testicular sperm extraction as the distal vas deferens (contralateral side) was obstructed. These findings showed that VE or cross VE remains an alternative treatment for CUAVD patients with OA, even with a relatively low rate of patency and natural pregnancy.
Pregnancy ; Female ; Humans ; Male ; Vas Deferens/abnormalities* ; Azoospermia/surgery* ; Epididymis/surgery* ; Retrospective Studies ; Tertiary Care Centers ; China ; Semen

OBJECTIVE: To observe the clinical therapeutic effect on functional erectile dysfunction (FED) of kidney deficiency and liver stagnation treated by METHODS: A total of 120 patients with FED were randomized into an observation group (60 cases, 2 cases dropped off) and a control group (60 cases, 4 cases dropped off). In the control group, the patients were treated with oral RESULTS: After treatment, the scores of IIEF5, EHS and EDITS were all increased as compared with the values before treatment ( CONCLUSION The combined therapy of
Drugs, Chinese Herbal/therapeutic use* ; Erectile Dysfunction/therapy* ; Humans ; Male ; Moxibustion ; Vascular Endothelial Growth Factor A

Objective To explore the data accuracy acquired by the anesthesia information management system.Methods Totally 100 patients from two hospitals were selected randomly,whose anesthesia time was estimated more than 1 h.The vital signs data acquired by the system were compared with those by the monitor once every 5 min±30 s,and totally there were 12 times of comparison executed.SAS 9.2 software was used for statistical analysis.Results In FAS set the system had the total data accuracy being 100％,95％ credibility interval from 86.87％ to 97.30％ and the BMDL higher than 85％;in PPS set he total data accuracy was 100％,95％ credibility interval was from 92.89％ to 100％ and the BMDL was also higher than 85％.The system gained "Excellent" or "Good" grade in system response,stability,functional interface operability and the accuracy of special functions.Conclusion The system acquires and stores the vital signs data automatically and accurately,enhances anesthesia information in objectivity,authenticity and tractability,and has high values for enhancing anesthesia safety,medical safety and scientific research.

OBJECTIVETo evaluate the sodium content and energy of commercial dishes in 4 Chinese restaurants in Beijing.

METHODSFrom June to August of 2011, 4 medium-sized restaurants were selected by convenience sampling method. Overall, 47 commercial dishes (including 9 cold dishes and 38 cooked dishes) consumed at least 6 times by consumers and provided by at least 2 restaurants were selected. One complete serving was selected for each dish to investigate its energy and sodium content, and calculate its sodium density.

RESULTSThe median value of sodium content in cold dishes and cooked dishes were 580, 522 mg/100 g (Z = 0.83, P > 0.05) or 1427, 2301 mg/serving (Z = 2.03, P < 0.05); the median sodium density for cold and cooked dishes were 1902 and 670 mg/1000 kJ (Z = 2.81, P < 0.01); the median value of energy in cold dishes and cooked dishes were 514, 717 kJ/100 g (Z = 2.15, P < 0.05) or 1113, 3492 kJ/serving (Z = 4.03, P < 0.05). Of the 47 dishes, 46.8% (22/47) exceeded the daily recommendation of sodium content for Chinese residents (2200 mg).

CONCLUSIONThe commercial dishes in medium-sized Chinese restaurants provide a relatively higher energy and sodium. Cold dishes contain less energy but have high sodium density, so the sodium from these dishes could not be ignored.

China ; Cooking ; Energy Intake ; Food Analysis ; Restaurants ; Sodium, Dietary ; analysis

BACKGROUNDA five-year follow-up study of intensive multifactorial intervention was undertaken to assess the changes of circulating serum amyloid A (SAA) levels and the incidence of atherosclerosis (AS) in patients with short-duration type 2 diabetes mellitus (T2DM) without macroangiopathy, and whether intensive multifactorial intervention could prevent or at least postpone the occurrence of macroangiopathy.

METHODSAmong 150 patients with short-duration T2DM, 75 were assigned to receive conventional outpatient treatment (conventional group) and the others underwent intensive multifactorial integrated therapy targeting hyperglycemia, hypertension, dyslipidemia and received aspirin simultaneously (intensive group).

RESULTSPlasma SAA levels were higher in diabetic patients than those in healthy control subjects, and decreased obviously after intensive multifactorial intervention. The levels of SAA were positively correlated with body mass index (BMI), waist hip ratio (WHR), triglyceride (TG), high sensitive C-reactive protein (hs-CRP) and common carotid intima-media thickness (CC-IMT). The standard-reaching rates of glycemia, blood pressure and lipidemia were significantly higher in intensive group than those of conventional group. The incidence of macroangiopathy decreased by 58.96% in intensive group compared with conventional group.

CONCLUSIONSIntensive multifactorial intervention may significantly reduce the SAA levels and prevent the occurrence of AS in short-duration patients with T2DM. SAA might be one of the risk factors of T2DM combined with AS.

Adult ; Aged ; Antihypertensive Agents ; pharmacology ; therapeutic use ; Blood Glucose ; metabolism ; C-Reactive Protein ; metabolism ; Diabetes Mellitus, Type 2 ; complications ; drug therapy ; metabolism ; Diabetic Angiopathies ; etiology ; Female ; Humans ; Hypoglycemic Agents ; pharmacology ; therapeutic use ; Hypolipidemic Agents ; pharmacology ; therapeutic use ; Male ; Middle Aged ; Multivariate Analysis ; Serum Amyloid A Protein ; metabolism ; Triglycerides ; blood ; Tunica Media ; drug effects

OBJECTIVETo investigate the dietary phytosterol intake of elderly women in three different cities of China, and to compare the main dietary sources, so that to discuss the relationship of dietary phytosterol intake and serum lipids.

METHODSBased on the dietary pattern, women more than 50 years old from Beijing, Hefei and Urumchi were chosen as testers, 80 - 100 people for each city respectively. The dietary survey was done by continues 24 hours review of two days, the plant food were collected and the phytosterol content (include beta-sitosterol, campesterol, stigmasterol, sitostanol) were analyzed by GC methods, the total phytosterols content were calculated. The dietary phytosterol intake were calculated and serum lipids were also analyzed in all the testers.

RESULTSTesters from Beijing, Hefei and Urumchi were 100, 101 and 84 respectively. The average dietary phytosterol intake of people in Beijing and Hefei were 340.3 mg/d and 313.5 mg/d, the main sources were plant oil and cereals, while the average dietary phytosterol intake of people in Urumchi were 550.4 mg/d, higher than the other two cities (t values were 9.369, 10.420, respectively, both P values < 0.01), the main source in Urumchi was cereal (provide 53.1% of the total phytosterol intake). The laboratory results showed, testers in Urumchi had significantly lower serum TC content ((4.04 +/- 0.78) mmol/L) than that in Beijing ((4.89 +/- 0.91) mmol/L) and Hefei ((4.71 +/- 0.83) mmol/L) (t value were 6.766 and 5.401 respectively, both P values < 0.01); serum TG content in Urumchi((1.01 +/- 0.48) mmol/L) was also lower than that in Beijing ((1.31 +/- 0.53) mmol/L) and Hefei ((1.66 +/- 0.75) mmol/L) (t values were 3.343 and 7.293 respectively, both P values < 0.01); the serum glucose is also lower in testers in Urumchi ((5.02 +/- 2.18) mmol/L) compared with testers in Beijing ((5.69 +/- 1.53) mmol/L, t = 2.561, P < 0.05) and Hefei ((5.78 +/- 1.53) mmol/L, t = 2.934, P < 0.01).

CONCLUSIONDifferent dietary pattern result in significantly different dietary phytosterol intake in elder women in three cities, higher, phytosterol intake seemed to contribute to lower serum lipids.

Aged ; Aged, 80 and over ; China ; Cholesterol ; analogs & derivatives ; blood ; Cholesterol, Dietary ; metabolism ; Female ; Humans ; Lipids ; blood ; Middle Aged ; Phytosterols ; blood ; metabolism ; Sitosterols ; blood ; Urban Population

Background A five-year follow-up study of intensive multifactorial intervention was undertaken to assess the changes of circulating serum amyloid A(SAA)levels and the incidence of atherosclerosis(AS)in patients with short-duration type 2 diabetes mellitus(T2DM)without maoroangiopathy,and whether intensive multifactorial intervention could prevent or at least postpone the occurence of macroangiopathy.Methods Among 150 patients with short-duration T2DM,75 were assigned to receive conventional outpatient treatment (conventional group)and the others underwent intensive multifactorial integrated therapy targeting hyperglycemia,hypertension,dyslipidemia and received aspirin simultaneously(intensive group).Results Plasma SAA levels were higher in diabetic patients than those in healthy control subjects,and decreased obviously after intensive multifactorial intervention.The levels of SAA were positively correlated with body mass index(BMI),waist hip ratio(WHR),triglyceride(TG),high sensitive C-reactive protein(hs-CRP)and common carotid intima-media thickness(CC-IMT).The standard-reaching rates of glycemia,blood pressure and lipidemia were significantly higher in intensive group than those of conventional group.The incidence of macroangiopathy decreased by 58.96% in intensive group compared with conventional group.Conclusions Intensive multifactorial intervention may significantly reduce the SAA levels and prevent the occurrence of AS in short-duration patients with T2DM.SAA might be one of the risk factors of T2DM combined with AS.

Objective To investigate the disease spectrum of Army Aviation helicopter pilots and provide suggestions to aeromedical service. Methods Cases of 516 helicopter pilots, who were in annual physical examination, were randomly sampled and divided into 3 groups by age. Process included reviewing diagnosis history, analyzing spectrum of disease and its distribution by age, as well as the prevalence of common diseases. Rank Sum Ratio was employed for comparing the distribution of common diseases in different age group. Results ① The top 10 diseases in helicopter pilots of the Army Aviation in 2006 were fatty liver (9.88%), hyperlipidemia (6.98%), gallbladder polypus (3.49%), lumbar disc herniation(2.33%), sinus bradycardia (2.33%), gall-stone(2.13%), chronic gastritis (1.74%), kidney cyst (1.55%), calcify of liver (1.36%) and hypertension (1.16%). ② The prevalence of fatty liver in each group was respectively 2.13%, 9. 29% and 45.59%, which was at a relative higher level The prevalence of fatty liver, chronic gastritis, hyperlipidemia, gallbladder polypus, calcify of liver, hypertension and diabetes was significantly different from each age group. ③ The WR of 3 age groups was 0.7486 and it showed a good concordance of common diagnoses in each age group (χ~2=17.97, P<0.05). Conclusions ①The common diseases of helicopter pilot of Army Aviation are prevalent as common as those of Chinese Air Force pilot on the whole. Compared to more frequent prevalence in other military pilots, no nero-related diseases appeared in the top 10 of helicopter pilots. ② The prevalence of fatty liver and hyperlipidemia increases rapidly with age. The accumulative effect of nosogenesis may exist and result in the diseases of lumber, back, neck and shoulder. ③ Rank Sum Ratio is an effective indication for comparing the concordance of common diagnoses in different group.

Objective To investigate the disease spectrum of Army Aviation helicopter pilots and provide suggestions to aeromedical service. Methods Cases of 516 helicopter pilots, who were in annual physical examination, were randomly sampled and divided into 3 groups by age. Process included reviewing diagnosis history, analyzing spectrum of disease and its distribution by age, as well as the prevalence of common diseases. Rank Sum Ratio was employed for comparing the distribution of common diseases in different age group. Results ① The top 10 diseases in helicopter pilots of the Army Aviation in 2006 were fatty liver (9.88%), hyperlipidemia (6.98%), gallbladder polypus (3.49%), lumbar disc herniation(2.33%), sinus bradycardia (2.33%), gall-stone(2.13%), chronic gastritis (1.74%), kidney cyst (1.55%), calcify of liver (1.36%) and hypertension (1.16%). ② The prevalence of fatty liver in each group was respectively 2.13%, 9. 29% and 45.59%, which was at a relative higher level The prevalence of fatty liver, chronic gastritis, hyperlipidemia, gallbladder polypus, calcify of liver, hypertension and diabetes was significantly different from each age group. ③ The WR of 3 age groups was 0.7486 and it showed a good concordance of common diagnoses in each age group (χ~2=17.97, P<0.05). Conclusions ①The common diseases of helicopter pilot of Army Aviation are prevalent as common as those of Chinese Air Force pilot on the whole. Compared to more frequent prevalence in other military pilots, no nero-related diseases appeared in the top 10 of helicopter pilots. ② The prevalence of fatty liver and hyperlipidemia increases rapidly with age. The accumulative effect of nosogenesis may exist and result in the diseases of lumber, back, neck and shoulder. ③ Rank Sum Ratio is an effective indication for comparing the concordance of common diagnoses in different group.