1.Development and application of diphtheria-tetanus-pertussis containing combined vaccines
Sha ZHANG ; Li LI ; Ruyue HU ; Lei CAO ; Xin LIU ; Jiakai YE ; Yifan SONG ; Zhaonan ZHANG ; Wenzhou YU
Chinese Journal of Epidemiology 2025;46(9):1667-1672
Combined vaccines can simplify the vaccination process, improve coverage rates, reduce the risk of adverse events following immunization, lower social costs, and improve the timeliness of childhood vaccination. This article focuses on multi-component vaccines based on the diphtheria-tetanus-pertussis containing vaccine. Globally, multiple combined vaccines have been developed and marketed, but the development of combined vaccine is still in its infancy stage in China, with limited vaccine types and doses available. The research, development, and application of combined vaccines still face numerous challenges in China, including technical challenges in research and development, as well as insufficient motivation for research and development. Additionally, the high cost of existing combined vaccines, coupled with low public awareness and weak vaccination intentions, significantly hinders their widespread application, China should continue to rigorously implement the Vaccine Administration Law of the People's Republic of China, promote innovative development of combined vaccines, increase public awareness, strengthen child guardians' confidence in vaccination, and improve the accessibility and affordability of combined vaccines to protect public health across all life stages.
2.Current status of vaccination among the elderly in China and improvement strategies to increase vaccination rates
Xin LIU ; Lijun LIU ; Ruyue HU ; Lei CAO ; Jiakai YE ; Sha ZHANG ; Li LI ; Yifan SONG ; Zhaonan ZHANG ; Wenzhou YU
Chinese Journal of Preventive Medicine 2025;59(9):1466-1470
The health and well-being of the elderly have become a focal point for all sectors of society. As an effective means of preventing and controlling infectious diseases, vaccination plays a critical role in safeguarding human health. For older adults, timely and scientifically guided vaccination can significantly reduce the risk of serious illnesses while alleviating the associated economic burdens and pressure imposed on society. However, in practice, deficiencies in policy support, accessibility of vaccination services, and public awareness hinder some elderly individuals from fully benefiting from the protective effects of vaccines. This paper analyzes current vaccination practices for the elderly globally and proposes strategies to improve vaccination coverage, providing a scientific basis for advancing effective vaccination initiatives for this demographic in China.
3.Practice, effectiveness and prospects of standardized management of vaccination clinics in China
Qingsong YU ; Li LI ; Lei CAO ; Jiakai YE ; Yifan SONG ; Zhaonan ZHANG ; Xiaoyu WANG ; Jiayu HE ; Rongna HUANG ; Liang WANG ; Wenzhou YU ; Zundong YIN
Chinese Journal of Preventive Medicine 2025;59(9):1454-1461
As an important setting for the administration of vaccinations, the reasonable setting up and standardized management of vaccination clinics will enhance immunization service quality, public satisfaction, and improve the vaccination rate to protect people′s health. In recent years, various provinces in China are continuously promoting the standardized construction and management of vaccination clinics. However, the level of standardization management remains unbalanced, and the capacity of vaccination services needs to be further improved. This paper reviews the standardized management process of vaccination clinics, summarizes the practice and achievements in various regions, and analyzes the challenges and issues during these processes, to provide reference for improving the standardized management level of vaccination clinics in the future.
4.Current status, challenges, and prospects of simultaneous vaccine administration in China′s childhood immunization strategy
Xin LIU ; Ruyue HU ; Jiakai YE ; Lei CAO ; Sha ZHANG ; Yifan SONG ; Zhaonan ZHANG ; Li LI ; Wenzhou YU
Chinese Journal of Preventive Medicine 2025;59(9):1462-1465
Vaccination has become one of the key public health interventions for reducing child mortality. With the implementation of the expanded programme on immunization, the number of vaccine types children need to receive is increasing, necessitating further optimization of childhood immunization strategies. The World Health Organization recommends simultaneous vaccination as one of the core strategies for optimizing childhood immunization schedules. This article analyzes the current status, challenges, and prospects of simultaneous vaccination strategies for children in China, aiming to provide a scientific basis for promoting and implementing strategies for the simultaneous administration of multiple vaccines to children.
5.Development and application of diphtheria-tetanus-pertussis containing combined vaccines
Sha ZHANG ; Li LI ; Ruyue HU ; Lei CAO ; Xin LIU ; Jiakai YE ; Yifan SONG ; Zhaonan ZHANG ; Wenzhou YU
Chinese Journal of Epidemiology 2025;46(9):1667-1672
Combined vaccines can simplify the vaccination process, improve coverage rates, reduce the risk of adverse events following immunization, lower social costs, and improve the timeliness of childhood vaccination. This article focuses on multi-component vaccines based on the diphtheria-tetanus-pertussis containing vaccine. Globally, multiple combined vaccines have been developed and marketed, but the development of combined vaccine is still in its infancy stage in China, with limited vaccine types and doses available. The research, development, and application of combined vaccines still face numerous challenges in China, including technical challenges in research and development, as well as insufficient motivation for research and development. Additionally, the high cost of existing combined vaccines, coupled with low public awareness and weak vaccination intentions, significantly hinders their widespread application, China should continue to rigorously implement the Vaccine Administration Law of the People's Republic of China, promote innovative development of combined vaccines, increase public awareness, strengthen child guardians' confidence in vaccination, and improve the accessibility and affordability of combined vaccines to protect public health across all life stages.
6.Current status of vaccination among the elderly in China and improvement strategies to increase vaccination rates
Xin LIU ; Lijun LIU ; Ruyue HU ; Lei CAO ; Jiakai YE ; Sha ZHANG ; Li LI ; Yifan SONG ; Zhaonan ZHANG ; Wenzhou YU
Chinese Journal of Preventive Medicine 2025;59(9):1466-1470
The health and well-being of the elderly have become a focal point for all sectors of society. As an effective means of preventing and controlling infectious diseases, vaccination plays a critical role in safeguarding human health. For older adults, timely and scientifically guided vaccination can significantly reduce the risk of serious illnesses while alleviating the associated economic burdens and pressure imposed on society. However, in practice, deficiencies in policy support, accessibility of vaccination services, and public awareness hinder some elderly individuals from fully benefiting from the protective effects of vaccines. This paper analyzes current vaccination practices for the elderly globally and proposes strategies to improve vaccination coverage, providing a scientific basis for advancing effective vaccination initiatives for this demographic in China.
7.Practice, effectiveness and prospects of standardized management of vaccination clinics in China
Qingsong YU ; Li LI ; Lei CAO ; Jiakai YE ; Yifan SONG ; Zhaonan ZHANG ; Xiaoyu WANG ; Jiayu HE ; Rongna HUANG ; Liang WANG ; Wenzhou YU ; Zundong YIN
Chinese Journal of Preventive Medicine 2025;59(9):1454-1461
As an important setting for the administration of vaccinations, the reasonable setting up and standardized management of vaccination clinics will enhance immunization service quality, public satisfaction, and improve the vaccination rate to protect people′s health. In recent years, various provinces in China are continuously promoting the standardized construction and management of vaccination clinics. However, the level of standardization management remains unbalanced, and the capacity of vaccination services needs to be further improved. This paper reviews the standardized management process of vaccination clinics, summarizes the practice and achievements in various regions, and analyzes the challenges and issues during these processes, to provide reference for improving the standardized management level of vaccination clinics in the future.
8.Current status, challenges, and prospects of simultaneous vaccine administration in China′s childhood immunization strategy
Xin LIU ; Ruyue HU ; Jiakai YE ; Lei CAO ; Sha ZHANG ; Yifan SONG ; Zhaonan ZHANG ; Li LI ; Wenzhou YU
Chinese Journal of Preventive Medicine 2025;59(9):1462-1465
Vaccination has become one of the key public health interventions for reducing child mortality. With the implementation of the expanded programme on immunization, the number of vaccine types children need to receive is increasing, necessitating further optimization of childhood immunization strategies. The World Health Organization recommends simultaneous vaccination as one of the core strategies for optimizing childhood immunization schedules. This article analyzes the current status, challenges, and prospects of simultaneous vaccination strategies for children in China, aiming to provide a scientific basis for promoting and implementing strategies for the simultaneous administration of multiple vaccines to children.
9.Thoughts and suggestions on digital services to enhance the level of vaccination management
Lin LUAN ; Na LIU ; Benfeng ZHENG ; Zhuoyu ZHANG ; Yifan SONG ; Li LI ; Ming GAN ; Lei CAO ; Zhuoying HUANG ; Jiakai YE ; Zhaonan ZHANG ; Xiaoxue LIU ; Junlei CHEN ; Changshuang WANG ; Bi CAI ; Wenzhou YU
Chinese Journal of Preventive Medicine 2024;58(2):159-165
With the development of information technology and the increasing demand for vaccination services among the people, it is a definite trend to enhance the quality of vaccination services through digitization. This article starts with a clear concept of digital services for vaccination, introduces the current development status in China and abroad, analyzes the advantages and disadvantages of existing models in leading regions, takes a glean from the summation, and proposes targeted solutions. This study suggests establishing a departmental coordination mechanism for data interconnection and sharing, formulating data standards and functional specifications, enhancing the functionalities of the immunization planning information system, strengthening data collection and analytical usage, and intensifying appointment management and science and health education to provide expert guidance for the construction of digital vaccination services across the country in the future.
10.Thoughts and suggestions on digital services to enhance the level of vaccination management
Lin LUAN ; Na LIU ; Benfeng ZHENG ; Zhuoyu ZHANG ; Yifan SONG ; Li LI ; Ming GAN ; Lei CAO ; Zhuoying HUANG ; Jiakai YE ; Zhaonan ZHANG ; Xiaoxue LIU ; Junlei CHEN ; Changshuang WANG ; Bi CAI ; Wenzhou YU
Chinese Journal of Preventive Medicine 2024;58(2):159-165
With the development of information technology and the increasing demand for vaccination services among the people, it is a definite trend to enhance the quality of vaccination services through digitization. This article starts with a clear concept of digital services for vaccination, introduces the current development status in China and abroad, analyzes the advantages and disadvantages of existing models in leading regions, takes a glean from the summation, and proposes targeted solutions. This study suggests establishing a departmental coordination mechanism for data interconnection and sharing, formulating data standards and functional specifications, enhancing the functionalities of the immunization planning information system, strengthening data collection and analytical usage, and intensifying appointment management and science and health education to provide expert guidance for the construction of digital vaccination services across the country in the future.

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