1.Effect of Huangqi Danzhi Shenmai Decoction in coronary atherosclerosis patients with qi deficiency and blood stasis syndrome and its impact on serum oxidative stress indicators and inflammatory factors
Yujiang WU ; Rongqi BAO ; Jiahao CHEN ; Jiayu YU ; Yueqing DAI
Journal of Clinical Medicine in Practice 2025;29(19):37-40,52
Objective To explore the effect of Huangqi Danzhi Shenmai Decoction in treatment of coronary atherosclerosis patients with qi deficiency and blood stasis syndrome and its influence on the levels of serum malondialdehyde(MDA),superoxide dismutase(SOD),tumor necrosis factor-α(TNF-α),and interleukin-1 β(IL-1β).Methods A total of 120 patients with coronary atheroscle-rosis were selected and randomly divided into control group(conventional treatment+simvastatin)and observation group(conventional treatment+Huangqi Danzhi Shenmai Decoction)by random number table method,with 60 cases in each group.The clinical efficacy of the two groups was evalua-ted.The changes in traditional Chinese medicine(TCM)syndrome scores,blood lipids,inflammatory factors,and oxidative stress indicators before and after treatment were recorded for both groups.Re-sults The total effective rate in the observation group was higher than that in the control group(P<0.05).After treatment,the TCM syndrome scores in the observation group were lower than those in the control group(P<0.05).The improvement in blood lipid indicators was more pronounced in the observation group compared to the control group(P<0.05).The serum levels of TNF-α,IL-1 β,and MDA in the observation group were lower than those in the control group,while the serum levels of SOD and glutathione peroxidase(GSH-PX)were higher than those in the control group,with statis-tically significant differences(P<0.05).No severe adverse reactions occurred in either group dur-ing the treatment period.Conclusion Huangqi Danzhi Shenmai Decoction has a good clinical effi-cacy in treating coronary atherosclerosis with qi deficiency and blood stasis syndrome,and can im-prove the oxidative stress status,reduce inflammatory responses,and regulate blood lipid levels in patients,so it is worthy of clinical promotion and use.
2.Application of virtual reality technology in the teaching of orthognathic surgery in the era of artificial intelligence
Jiahao BAO ; Mengjia CHENG ; Hongbo YU
Chinese Journal of Medical Education Research 2023;22(12):1761-1766
Owing to complex surgical planning and procedures, orthognathic surgery requires surgeons to possess a high level of clinical expertise. However, traditional teaching methods are difficult to meet the requirements for complex training on orthognathic surgical planning and operation. Virtual reality (VR) technology provides a new solution, but it is limited by problems like imprecise modeling, complex surgical design, single-simulated surgical contents, inability to integrate real time and simulation, and a lack of automatic evaluation function. Artificial intelligence (AI) is potent in data mining and image processing, which can address the limitations of traditional VR teaching, bringing multiple potential for clinical and educational application in orthognathic surgery. With research in personalized model construction, intelligent diagnostics, post-operative prediction, virtual surgical simulation, and personalized feedback and guidance, the fusion of "VR plus AI" holds promise for advancing orthognathic surgical teaching in a more precise and efficient direction, promoting the integration of medicine and technology, and speeding up the transformation of clinical applications.
3.ADC and relative ADC in differential diagnosis of lymphoma and metastasis in cervical lymph nodes
Jing ZHONG ; Cuifang CHEN ; Ying CHEN ; Jiahao LIN ; Daoliang BAO ; Yunbin CHEN
Chinese Journal of Medical Imaging Technology 2018;34(6):846-849
Objective To investigate the value of MR apparent diffusion coefficient (ADC) and relative apparent diffusion coefficient (rADC) in differential diagnosis of lymphoma and metastasis in cervical lymph nodes.Methods Totally 69 patients with lymphoma (lymphoma group) and 66 patients with cervical lymph nodes metastasis (metastasis group) underwent MR examination.ADC values of lymph nodes and the right masseter muscle were measured,and rADC values were calculated.The consistency between two observers was evaluated.The differences of ADC value and rADC value were compared between the two groups.The efficacy of ADC value and rADC value in differential diagnosis of lymphoma and metastasis in cervical lymph nodes was analyzed with ROC curve.Results The consistency between two observers was excellent (all ICC>0.9).Both ADC and rADC values of lymphoma group were significantly lower than those of metastasis group (all P<0.05).Taken ADC and rADC values as 0.702 × 10-3 mm2/s and 0.584,the sensitivity and specificity was 98.48 % and 89.39 %,76.81 % and 84.06 %,respectively.Conclusion ADC and rADC values are useful in discriminating lymphoma from metastatic lymph nodes.

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