1.Inflammatory Markers in the Early Course of Asymptomatic/ Mild Coronavirus Disease Patients With Schizophrenia Spectrum Disorder and Neurodevelopmental Disorder
Yeontaek OH ; Jonggook LEE ; Jejung LEE ; Heeyoung SEO ; Gyungmin KIM ; Keun OH
Korean Journal of Psychosomatic Medicine 2025;33(2):93-100
Objectives:
:This study aims to identify differences in the expression of early inflammatory markers according to psychiatric diagnosis in the early course of mild and asymptomatic COVID-19 confirmed patients.
Methods:
:The sample consisted of 79 COVID-19 patients hospitalized from January 1, 2022 to May 31, 2022, 78 patients were divided into three groups: schizophrenia spectrum disorder, neurodevelopmental disorder,and others. And inflammatory markers were obtained via blood tests that performed upon hospitalization. We compared inflammatory markers and analyze the correlation about age, gender and use of antipsychotic drugs was confirmed.
Results:
:Neutrophil fraction was increased in the schizophrenia spectrum group and the neurodevelopmental disorder group compared to others(Schizophrenia=56.2±12.3, Neurodevelopmental disorder=56.0±11.7, Other=44.5±8.3, p=0.009). However, other inflammatory markers showed no difference in the three groups. Correlation analysis confirmed the association between age and Neutrophil fraction (r2 =0.113, 0.336, p<0.01) and free T4 (r2 =0.073, 0.270, p<0.05), but all had only weak explanatory power.
Conclusions
:Most inflammatory markers did not show significant differences depending on the patient group.There are several studies reporting that COVID-19 is highly associated with a negative prognosis in patients withschizophrenia or intellectual disability, but no significant differences in inflammatory markers by patient groups in the early course of mild and asymptomatic COVID-19 confirmed patients. suggesting that additional research onthe course of the disease is needed.
2.The effects of total and supracervical hysterectomy on sexual function.
Heajoong CHO ; Jejung LEE ; Seongnam PARK ; Sanghun JUNG ; Kyunghee KO ; Giyeon HONG
Korean Journal of Obstetrics and Gynecology 2005;48(2):428-435
OBJECTIVE: The aim of this study was to analyze the effects of total abdominal hysterectomy (TAH) versus supracervical hysterectomy (SCH) on sexual function in patients with non-malignant conditions. METHODS: We choose fifty patients who were operated by SCH and forty-six patients who were operated by TAH. They were interviewed that effects of the two operations on sexual desire, coital frequency, quality and frequency of orgasms, post-op development of dyspareunia and overall sexual satisfaction. RESULTS: 1. The sexual desire significantly decreased in TAH group compared with SCH group (46% vs 8%, P<0.001). And the coital frequency also decreased in TAH group (48% vs 6%, P<0.001). 2. Orgasm frequency and quality decreased in more patients with TAH compared with SCH (22% vs 2%, 33% vs 2%). 3. After SCH and TAH, there was no change in dyspareunia and significantly decreased sexual satisfaction was noted in TAH group (35% vs 4%). CONCLUSION: It suggest that TAH patients experienced worse postoperative sexual function than SCH patients. therefore, it should be considered to conserving the cervix at hysterectomy.
Cervix Uteri
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Coitus
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Dyspareunia
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Female
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Humans
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Hysterectomy*
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Orgasm
3.A Case of Choriocarcinoma after Evacuation of Partial Mole.
Hyun CHO ; Jejung LEE ; Hajung CHO ; Kyunghee KO ; Hyungbae MOON ; Heunggon KIM
Korean Journal of Obstetrics and Gynecology 2004;47(12):2511-2514
Persistent gestational trophoblastic tumor develops in about 15-25% after evacuation of complete mole, and arises in about 4-5% after removal of partial mole. Especially there is reported that choriocarcinoma after evacuation of partial mole is extremely rare, and it is well responded to systemic chemotherapy. We have experienced that a case of choriocarcinoma which was developed after evacuation of partial mole. So we report this case with a brief review of literatures.
Choriocarcinoma*
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Drug Therapy
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Female
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Pregnancy
;
Trophoblastic Neoplasms

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