Purpose: This study investigated the levels of delirium knowledge, delirium nursing-related stress, emotional intelligence, and delirium nursing competency among nurses in integrated nursing care wards, and aimed to identify factors influencing their competency. Methods: A descriptive survey design was employed, and data were collected from 184 nurses working in integrated nursing care wards at general hospitals located in Seoul and Daejeon, South Korea. The research instruments included measures of delirium knowledge, delirium nursing-related stress, emotional intelligence, and delirium nursing competency. Results: Delirium knowledge, emotional intelligence, and experience with delirium education were significant influencing factors, explaining 12% of the variance on delirium nursing competency. Conclusion Based on these findings, it is recommended that future research within the field of nursing should explore a broader range of variables that may influence delirium nursing competency, particularly among nurses working in integrated nursing settings. In addition, from the perspective of foundational nursing education, it is necessary to conduct experimental studies and develop targeted educational programs aimed at reaching a deeper understanding of the various mechanisms underlying delirium.

Purpose: This study investigated the levels of delirium knowledge, delirium nursing-related stress, emotional intelligence, and delirium nursing competency among nurses in integrated nursing care wards, and aimed to identify factors influencing their competency. Methods: A descriptive survey design was employed, and data were collected from 184 nurses working in integrated nursing care wards at general hospitals located in Seoul and Daejeon, South Korea. The research instruments included measures of delirium knowledge, delirium nursing-related stress, emotional intelligence, and delirium nursing competency. Results: Delirium knowledge, emotional intelligence, and experience with delirium education were significant influencing factors, explaining 12% of the variance on delirium nursing competency. Conclusion Based on these findings, it is recommended that future research within the field of nursing should explore a broader range of variables that may influence delirium nursing competency, particularly among nurses working in integrated nursing settings. In addition, from the perspective of foundational nursing education, it is necessary to conduct experimental studies and develop targeted educational programs aimed at reaching a deeper understanding of the various mechanisms underlying delirium.

Purpose: This study investigated the levels of delirium knowledge, delirium nursing-related stress, emotional intelligence, and delirium nursing competency among nurses in integrated nursing care wards, and aimed to identify factors influencing their competency. Methods: A descriptive survey design was employed, and data were collected from 184 nurses working in integrated nursing care wards at general hospitals located in Seoul and Daejeon, South Korea. The research instruments included measures of delirium knowledge, delirium nursing-related stress, emotional intelligence, and delirium nursing competency. Results: Delirium knowledge, emotional intelligence, and experience with delirium education were significant influencing factors, explaining 12% of the variance on delirium nursing competency. Conclusion Based on these findings, it is recommended that future research within the field of nursing should explore a broader range of variables that may influence delirium nursing competency, particularly among nurses working in integrated nursing settings. In addition, from the perspective of foundational nursing education, it is necessary to conduct experimental studies and develop targeted educational programs aimed at reaching a deeper understanding of the various mechanisms underlying delirium.

Purpose: This study investigated the levels of delirium knowledge, delirium nursing-related stress, emotional intelligence, and delirium nursing competency among nurses in integrated nursing care wards, and aimed to identify factors influencing their competency. Methods: A descriptive survey design was employed, and data were collected from 184 nurses working in integrated nursing care wards at general hospitals located in Seoul and Daejeon, South Korea. The research instruments included measures of delirium knowledge, delirium nursing-related stress, emotional intelligence, and delirium nursing competency. Results: Delirium knowledge, emotional intelligence, and experience with delirium education were significant influencing factors, explaining 12% of the variance on delirium nursing competency. Conclusion Based on these findings, it is recommended that future research within the field of nursing should explore a broader range of variables that may influence delirium nursing competency, particularly among nurses working in integrated nursing settings. In addition, from the perspective of foundational nursing education, it is necessary to conduct experimental studies and develop targeted educational programs aimed at reaching a deeper understanding of the various mechanisms underlying delirium.

This research group (forensic research via omics markers in environmental health vulnerable areas: FROM) aimed to develop biomarkers for exposure to environmental hazards and diseases, assess environmental diseases, and apply and verify these biomarkers in environmentally vulnerable areas. Environmentally vulnerable areas—including refineries, abandoned metal mines, coal-fired power plants, waste incinerators, cement factories, and areas with high exposure to particulate matter—along with control areas, were selected for epidemiological investigations. A total of 1,157 adults, who had resided in these areas for over 10 years, were recruited between June 2021 and September 2023. Personal characteristics of the study participants were gathered through a survey. Biological samples, specifically blood and urine, were collected during the field investigations, separated under refrigerated conditions, and then transported to the laboratory for biomarker analysis. Analyses of heavy metals, environmental hazards, and adducts were conducted on these blood and urine samples. Additionally, omics analyses of epigenomes, proteomes, and metabolomes were performed using the blood samples. The biomarkers identified in this study will be utilized to assess the risk of environmental disease occurrence and to evaluate the impact on the health of residents in environmentally vulnerable areas, following the validation of diagnostic accuracy for these diseases.

This research group (forensic research via omics markers in environmental health vulnerable areas: FROM) aimed to develop biomarkers for exposure to environmental hazards and diseases, assess environmental diseases, and apply and verify these biomarkers in environmentally vulnerable areas. Environmentally vulnerable areas—including refineries, abandoned metal mines, coal-fired power plants, waste incinerators, cement factories, and areas with high exposure to particulate matter—along with control areas, were selected for epidemiological investigations. A total of 1,157 adults, who had resided in these areas for over 10 years, were recruited between June 2021 and September 2023. Personal characteristics of the study participants were gathered through a survey. Biological samples, specifically blood and urine, were collected during the field investigations, separated under refrigerated conditions, and then transported to the laboratory for biomarker analysis. Analyses of heavy metals, environmental hazards, and adducts were conducted on these blood and urine samples. Additionally, omics analyses of epigenomes, proteomes, and metabolomes were performed using the blood samples. The biomarkers identified in this study will be utilized to assess the risk of environmental disease occurrence and to evaluate the impact on the health of residents in environmentally vulnerable areas, following the validation of diagnostic accuracy for these diseases.

This research group (forensic research via omics markers in environmental health vulnerable areas: FROM) aimed to develop biomarkers for exposure to environmental hazards and diseases, assess environmental diseases, and apply and verify these biomarkers in environmentally vulnerable areas. Environmentally vulnerable areas—including refineries, abandoned metal mines, coal-fired power plants, waste incinerators, cement factories, and areas with high exposure to particulate matter—along with control areas, were selected for epidemiological investigations. A total of 1,157 adults, who had resided in these areas for over 10 years, were recruited between June 2021 and September 2023. Personal characteristics of the study participants were gathered through a survey. Biological samples, specifically blood and urine, were collected during the field investigations, separated under refrigerated conditions, and then transported to the laboratory for biomarker analysis. Analyses of heavy metals, environmental hazards, and adducts were conducted on these blood and urine samples. Additionally, omics analyses of epigenomes, proteomes, and metabolomes were performed using the blood samples. The biomarkers identified in this study will be utilized to assess the risk of environmental disease occurrence and to evaluate the impact on the health of residents in environmentally vulnerable areas, following the validation of diagnostic accuracy for these diseases.

This research group (forensic research via omics markers in environmental health vulnerable areas: FROM) aimed to develop biomarkers for exposure to environmental hazards and diseases, assess environmental diseases, and apply and verify these biomarkers in environmentally vulnerable areas. Environmentally vulnerable areas—including refineries, abandoned metal mines, coal-fired power plants, waste incinerators, cement factories, and areas with high exposure to particulate matter—along with control areas, were selected for epidemiological investigations. A total of 1,157 adults, who had resided in these areas for over 10 years, were recruited between June 2021 and September 2023. Personal characteristics of the study participants were gathered through a survey. Biological samples, specifically blood and urine, were collected during the field investigations, separated under refrigerated conditions, and then transported to the laboratory for biomarker analysis. Analyses of heavy metals, environmental hazards, and adducts were conducted on these blood and urine samples. Additionally, omics analyses of epigenomes, proteomes, and metabolomes were performed using the blood samples. The biomarkers identified in this study will be utilized to assess the risk of environmental disease occurrence and to evaluate the impact on the health of residents in environmentally vulnerable areas, following the validation of diagnostic accuracy for these diseases.

Objective: This study aimed to identify the factors affecting posttraumatic stress disorder (PTSD) symptom remission prospectively through a 1-year follow-up of sexual assault (SA) victims. Methods: A total 65 female SA victims who visited the crisis intervention center were included. Self-administered questionnaires regarding PTSD symptoms and PTSD related prognostic factors were conducted at both recruitment (T1) and 1 year after recruitment (T2). The multivariate analyses were used to determine the significant predictors of PTSD remissionon-remission state 1 year after SA. Results: In logistic regression analysis, both anxiety and secondary victimization were identified as significant factors explaining the results on PTSD remissionon-remission state at T2 (Beck’s Anxiety Inventory [BAI], p=0.003; Secondary Victimization Questionnaire, p=0.024). In a linear mixed analysis, both depression and anxiety were found to be significant variables leading to changes in Posttraumatic Diagnostic Scale for Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition from T1 to T2 (BAI, p<0.001; Center for Epidemiological Studies Depression Scale, p<0.001). Conclusion Depression, anxiety symptoms, and secondary victimization after SA were associated with PTSD symptom non-remission 1 year after SA.

Background: and Purpose Fingolimod (FTY) inhibits lymphocyte egress from lymphoid organs to cause lymphopenia, but the clinical implications of FTY-induced lymphopenia are not fully understood. We aimed to determine the frequency and severity of lymphopenia during FTY treatment among Korean patients with multiple sclerosis (MS), and its association with infections. Methods: We retrospectively reviewed the medical records of patients with MS treated using FTY from 12 referral centers in South Korea between March 2013 and June 2021. Patients were classified according to their nadir absolute lymphocyte count (ALC) during treatment:grade 1, 800–999/μL; grade 2, 500–799/μL; grade 3, 200–499/μL; and grade 4, <200/μL. Results: FTY treatment was administered to 69 patients with a median duration of 18 months (range=1–169 months), with 11 patients being treated for ≥7 years. During FTY treatment, mean ALCs were reduced after the first month (653.0±268.9/μL, mean±standard deviation) (p<0.0001) and remained low during treatment lasting up to 84 months. During follow-up, 41 (59.4%) and 7 (10.1%) patients developed grade-3 and grade-4 lymphopenia, respectively.No significant difference was found in age at FTY initiation, sex, baseline ALC, body mass index, or prior disease-modifying treatment between patients with and without grade-4 lymphopenia. Infections were observed in 11 (15.9%) patients, and the frequencies of patients with and without grade-4 lymphopenia were similar. Conclusions FTY treatment induced grade-4 lymphopenia in 10% of South Korean patients with MS, but did not appear to be associated with an increased infection risk.