This paper describes a multidisciplinary management approach on a case of a 20 year old nulligravid who was diagnosed with both cervicovaginal agenesis and causal regression syndrome (CRS). The index patient mainly presented with complaints of failed vaginal penetration, amenorrhea and cyclic monthly pelvic pain. The coexistence of cervicovaginal agenesis and CRS is extremely rare, and the pathogenesis regarding the association of both conditions is not yet fully understood. This combination poses significant diagnostic and management challenges, requiring a multidisciplinary approach that includes reproductive medicine, radiology, neurosurgery, orthopedics, and psychological support. Surgical reconstruction remains highly complex and individualized due to anatomical and functional constraints.

Human ; Female ; Young Adult: 19-24 Yrs Old ; Amenorrhea