No abstract available.
Epidermal Cyst* ; Herpes Zoster*

No abstract available.
Knee* ; Nevus* ; Organoids*

Proliferating trichilemmal tumor (PTT) is an uncommon neoplasm originated from the outer root sheath of a hair follicle. Malignant transformation occurs occasionally in proliferating trichilemmal tumors, which can be manifested by sudden rapid growths. Histologically, the malignant proliferating trichilemmal tumors (MPTTs) have shown severe nuclear atypia, marked cellular pleomorphism with atypical mitoses, dyskeratotic cells and infiltrating margins. Squamous cell carcinoma (SCC) should be differentiated with MPTT which indicates characteristic trichilemmal keratinization. Large tumor is considered as a risk factor of metastasis in SCC, but the relationship between tumor size and metastasis in the MPTT is not yet clarified. In this report, two patients have large erythematous nodules with focal ulceration and necrosis on their scalps and were diagnosed as MPTT. Despite the large sizes of the tumors, there were no evidences of metastases. Herein, we report 2 cases of the large MPTT which are presented without metastasis.
Carcinoma, Squamous Cell ; Hair Follicle ; Humans ; Mitosis ; Necrosis ; Neoplasm Metastasis* ; Risk Factors ; Scalp* ; Ulcer

No abstract available.
Dermatitis, Allergic Contact

No abstract available.
Angiofibroma ; Carbon ; Carbon Dioxide ; Lasers, Gas

No abstract available.
Adult ; Humans

BACKGROUND: Acquired bilateral nevus of Ota-like macules (ABNOM) is a dermal pigmented lesion common in individuals of Oriental origin. The Q-switched Nd:YAG laser (QSNYL) has been used successfully to treat a variety of benign, dermal, pigmented lesions, including nevus of Ota lesions. The similarity between ABNOM and nevus of Ota suggested that QSNYL may also be effective in the former. OBJECTIVE: To determine the efficacy and side-effect profiles of QSNYL treatment of ABNOM in Korean patients. METHODS: Of 42 Korean patients with ABNOM, 29 were treated with QSNYL (1,064 nm, 3 mm spot size, fluence 8~9.5 J/cm2), for up to 10 sessions each. Clinical photographs were taken before and after treatment. Lesion clearance was graded and complications such as hyperpigmentation, scarring, hypopigmentation, and erythema were assessed. RESULTS: Of the 29 treated patients, 19 (66%) showed excellent or good results. Of the patients who were treated more than 3 times, 76% showed good to excellent results. Two patients experienced post-laser hyperpigmentation (PLH), which persisted for more than one month, but no patient experienced persistent erythema or hypertrophic scarring. CONCLUSION: QSNYL is safe and effective in the treatment of ABNOM in Korean patients. Short-interval repetitive treatment is especially useful in improving therapeutic results and reducing PLH.
Cicatrix ; Cicatrix, Hypertrophic ; Erythema ; Humans ; Hyperpigmentation ; Hypopigmentation ; Laser Therapy ; Nevus ; Nevus of Ota

Extraskeletal Ewing's sarcoma has been recognized as being histologically indistinguishable from Ewing's sarcoma of bone. Histopathologically, Ewing's sarcoma consists of solid sheets of small round cells with vesicular nuclei and scant cytoplasm, and the cells are arranged in irregular masses separated by strands of fibrous tissue. Extraskeletal Ewing's sarcoma may arise virtually anywhere, but it is most common in the deep soft tissues of the extremities. We report here on a 27-year-old woman with cutaneous extraskeletal Ewing's sarcoma. She presented with a subcutaneous tumor of the right upper arm, and this was without osseous involvement. The patient underwent wide local excision and she received chemotherapy with vincristine, cyclophosphamide, etoposide and ifosfamide. There has been no evidence of recurrence or metastasis during 16 months of follow up.
Adult ; Arm ; Cyclophosphamide ; Cytoplasm ; Etoposide ; Extremities ; Female ; Follow-Up Studies ; Humans ; Ifosfamide ; Neoplasm Metastasis ; Recurrence ; Sarcoma, Ewing ; Skin ; Vincristine

Calcifying aponeurotic fibroma is an unusual, but well-characterized soft tissue tumor that typically involves the extremities. The age at presentation ranges from birth to 64 years of age. However, the majority of cases are seen in children with a median age of 12 years. Histologically, this tumor shows a poorly circumscribed, fibrotic mass extending into fat with areas of dense hyalinization, fibrosis and scattered calcification. Due to its infiltrative growth, calcifying aponeurotic fibroma has a high rate of local recurrence after surgical treatment. We recently encountered a 53-year-old Korean man with a solitary, hyperkeratotic, subcutaneous nodule on the sole of his foot. After histopathologic examination, the lesion was diagnosed as calcifying aponeurotic fibroma. During the follow-up period for 3 months, there was no increase in size of the lesion.
Adult ; Child ; Extremities ; Fibroma ; Fibrosis ; Follow-Up Studies ; Foot ; Humans ; Hyalin ; Middle Aged ; Parturition ; Recurrence

Trichodiscoma are hamartomas of the dermal portion of the hair disc, and these are found as asymptomatic flesh- colored papules 1~3 mm in diameter, and they are usually located on the face, trunk and thigh. Histopathologically, this is characterized by non-encapsulated fibrovascular lesion with a myxoid stroma surrounded by folliculo- sebaceous units. Birt-Hogg-Dube syndrome, which develops multiple trichodiscomas with fibrofolliculomas and skin tags, has been described. The case of solitary trichodischoma is rare. We recently encountered a 29-year-old woman with a solitary, dome-shaped papule on the right thigh. After histopathologic examination, the lesion was diagnosed as trichodiscoma.
Adult ; Birt-Hogg-Dube Syndrome ; Female ; Hair ; Hamartoma ; Humans ; Skin ; Thigh