Purpose: Atherosclerotic plaques in peripheral arterial disease (PAD) include fatty, mixed, and calcified types. Plaque burden is significantly associated with restenosis, reintervention, and amputation-free survival. Rotational and aspirational atherectomy (RAA) may effectively remove such plaques. This study aimed to evaluate long-term outcomes of RAA for infrainguinal PAD. Methods: Patients with infrainguinal lesions underwent revascularization using the Jetstream Atherectomy System (Boston Scientific). This 60-month extension assessed primary patency rate (PPR) and clinically driven target lesion revascularization (CD-TLR). Kaplan-Meier curves were used for survival analysis; P < 0.05 was considered statistically significant. Results: A total of 150 patients (mean age, 70.9 years; male, 86.0%; 65.4% with diabetes) were enrolled. The mean lesion length was 15.8 cm, with 74.0% occlusions and 47.3% severe calcification. Lesions were sclerotic (72.4%), thrombosclerotic (13.4%), thrombotic (9.4%), or in-stent (4.7%). A drug-coated balloon (DCB) was used in 85.5% of cases. PPR at 1, 3, and 5 years was 84.1%, 68.1%, and 58.5%, respectively. CD-TLR rates were 93.0%, 81.5%, and 67.4%, respectively. The benefit of DCB was sustained through 3 years but attenuated thereafter, highlighting the need for extended follow-up in infrainguinal interventions. Conclusion RAA demonstrated durable 5-year patency and safety outcomes. Device type, DCB use, lesion morphology, and calcium grade did not significantly influence long-term results. Lesion complexity remains the primary predictor of clinical outcome. Despite the complexity of infrainguinal lesions, the use of RAA demonstrated sustained patency through 3 years, with lesion complexity (particularly TASC classification) emerging as the most critical predictor of long-term success.

Purpose: To evaluate the efficacy and safety of latanoprostene bunod 0.024% (LBN) in Korean patients with glaucoma or ocular hypertension in a real-world clinical setting. Methods: This retrospective study included patients who initiated LBN treatment between March 1, 2022, and December 31, 2024. Patients were categorized into monotherapy, switched therapy, and concomitant therapy groups. Changes in intraocular pressure (IOP) were assessed at baseline, month 1, and month 6 according to treatment group and diagnosis. The type and frequency of adverse events were also analyzed. Results: Among the 138 patients initially identified, 129 were included in the analysis. The mean IOP for all patients was 17.4 ± 4.9 mmHg at baseline, 16.0 ± 4.6 mmHg at month 1, and 14.6 ± 3.7 mmHg at month 6. The mean IOP reduction was -1.4 ± 2.8 mmHg at month 1 (p < 0.001) and -2.2 ± 3.3 mmHg at month 6 (p < 0.001). Subgroup analyses by treatment type (monotherapy, switched, and concomitant) and diagnosis revealed significant IOP reductions at both time points across all groups. Adverse events occurred in 22 patients (17.1%), with eye pain being the most frequent. No serious adverse events were observed, including systemic side effects, severe visual impairment, or significant ocular complications. Conclusions LBN significantly reduced IOP in Korean patients with glaucoma and ocular hypertension, irrespective of prior IOP-lowering medication use and was well tolerated with a favorable safety profile. These findings support the use of LBN as an effective treatment option for Korean patients with glaucoma or ocular hypertension in diverse clinical settings.

Cutaneous pseudolymphoma refers to a group of benign lymphoid proliferations that mimic cutaneous lymphomas clinically and histologically. Here, we describe a case involving a 13-year-old boy who presented with an asymptomatic, solitary, dome-shaped, skin-colored nodule on the left lower eyelid, initially suspected to be a soft fibroma or neurofibroma. Histopathological examination with immunohistochemical analysis showed a dense dermal lymphoid infiltrate predominantly composed of CD3＋, CD5＋ T cells, interspersed with CD20＋ B cells and CD38＋ plasma cells, without evidence of light chain restriction on kappa/lambda in situ hybridization. We diagnosed the lesion as cutaneous pseudolymphoma. Given the benign nature and previous unsuccessful topical treatments, we began treatment with intralesional corticosteroid therapy (triamcinolone acetonide, 5 mg/mL), resulting in significant clinical improvement within 1 month. This case underscores the importance of comprehensive histologic and immunophenotypic assessments to differentiate pseudolymphoma from early-stage cutaneous lymphomas, particularly in pediatric patients.

Background and Objectives: Transseptal punctures (TSPs) are usually performed during cardiac interventions. Due to the associated risks during various procedural steps, mastering the technique requires a standardized training process and a significant learning curve, built on extensive experience. This study aimed to evaluate the safety and effectiveness of radiofrequency (RF)-powered transseptal needles during electrophysiological procedures, with the ultimate goal of implementing standardized and safe TSP methods. Methods: This study included all patients scheduled for atrial fibrillation catheter ablation requiring TSP for left atrial (LA) access from January to June 2024 at our centre. Preprocedural assessments included transthoracic echocardiography and cardiac computed tomography (CT). A dual-monitoring system with intracardiac echocardiography and pressure monitoring was used. Ten patients (male, n = 8; female, n = 2) underwent TSP using RF-powered needles without any complications. Results: The average LA volume measured by CT was 216.9 cm 3 , and the average LA volume index was 55.2 mL/m 2 , indicating severe atrial enlargement. The RF-powered TSP needle allowed precise guidance and minimized the risk of injury to adjacent cardiac structures.The dual-monitoring system enhanced TSP safety and accuracy. Conclusions Assistive devices and coincidental imaging monitoring modalities can be beneficial in cases involving complex anatomical cardiac structures that require intricate TSP. The RF-powered needle can aid in redoing TSP procedures and those with anatomical difficulties and variations. A standardized guide for safe TSP tailored to a specific procedure is recommended to enhance procedural success and safety.

Acquired dermal melanocytosis, characterized by the presence of melanocytes in the dermis, varies in the timing and location of occurrence. While congenital cases, such as Mongolian spots, nevus of Ota, nevus of Ito, and blue nevus, are common, acquired cases also occur. Acquired bilateral nevus of Ota-like macules is relatively common in Asians;however, extrafacial cases, particularly those involving both the face and extremities, are extremely rare. We report the case of a 66-year-old man with symmetric pigmented patches on the scalp, face, shoulders, and dorsa of the hands for 9 months, following the onset of spots on the forehead and nose that progressively spread. Notably, nasal ala pigmentation was confirmed. Histopathological examination revealed scattered melanin-containing dendritic cells in the upper dermis. Based on the clinicopathological findings, he was diagnosed with acquired dermal melanocytosis of the face and extremities, representing a rare case.

Marjolin’s ulcer is a rare but aggressive form of skin cancer that often presents significant surgical challenges due to the complex anatomy of the pelvis and the necessity for wide excision to avoid recurrence. This case report highlights the innovative use of a 3-dimensional (3D)–printed model for the precise planning and successful execution of a high partial sacrectomy in a 48-year-old male patient with quadriplegia. This patient, who had sustained a cervical spine injury in 1996, developed a sacral pressure sore that progressed into a Marjolin's ulcer. Utilizing high-resolution 3D computed tomography scans, we created a detailed 3D-printed model of the patient's sacrum, which facilitated a thorough understanding of the tumor's anatomy and its spatial relationships with critical structures. This approach significantly aided the surgical team in executing a challenging excision while minimizing risk to the adjacent organs. This case underscores the potential of 3D printing technology to enhance surgical planning and outcomes in complex oncological resections, particularly in anatomically challenging regions.

Ganglion cysts originating from the volar wrist joint are usually found on the volar side. A case report has described a patient with a dorsal wrist ganglion originating from the scapholunate ligament and appearing at a volar location. However, no cases of volar wrist ganglia appearing on the dorsal wrist have been reported. Herein, we present a rare case of a large dorsal ganglion cyst originating from the volar scaphotrapeziotrapezoidal (STT) joint that pierced the first dorsal interosseous muscle, leading to dorsal bulging. A 40-year-old woman presented with a progressively growing mass over the dorsal aspect of her left wrist and mild pain. Preoperative imaging showed a ganglion cyst originating from the volar side of the STT joint. The ganglion was successfully removed through open surgery. In conclusion, since ganglion cysts occurring in the dorsal wrist, especially if there is deviation to the radial side, may originate from the volar midcarpal joint, magnetic resonance imaging is necessary to reduce the risk of recurrence and minimize the likelihood of postoperative complications.

Acquired dermal melanocytosis, characterized by the presence of melanocytes in the dermis, varies in the timing and location of occurrence. While congenital cases, such as Mongolian spots, nevus of Ota, nevus of Ito, and blue nevus, are common, acquired cases also occur. Acquired bilateral nevus of Ota-like macules is relatively common in Asians;however, extrafacial cases, particularly those involving both the face and extremities, are extremely rare. We report the case of a 66-year-old man with symmetric pigmented patches on the scalp, face, shoulders, and dorsa of the hands for 9 months, following the onset of spots on the forehead and nose that progressively spread. Notably, nasal ala pigmentation was confirmed. Histopathological examination revealed scattered melanin-containing dendritic cells in the upper dermis. Based on the clinicopathological findings, he was diagnosed with acquired dermal melanocytosis of the face and extremities, representing a rare case.

Ganglion cysts originating from the volar wrist joint are usually found on the volar side. A case report has described a patient with a dorsal wrist ganglion originating from the scapholunate ligament and appearing at a volar location. However, no cases of volar wrist ganglia appearing on the dorsal wrist have been reported. Herein, we present a rare case of a large dorsal ganglion cyst originating from the volar scaphotrapeziotrapezoidal (STT) joint that pierced the first dorsal interosseous muscle, leading to dorsal bulging. A 40-year-old woman presented with a progressively growing mass over the dorsal aspect of her left wrist and mild pain. Preoperative imaging showed a ganglion cyst originating from the volar side of the STT joint. The ganglion was successfully removed through open surgery. In conclusion, since ganglion cysts occurring in the dorsal wrist, especially if there is deviation to the radial side, may originate from the volar midcarpal joint, magnetic resonance imaging is necessary to reduce the risk of recurrence and minimize the likelihood of postoperative complications.

Acquired dermal melanocytosis, characterized by the presence of melanocytes in the dermis, varies in the timing and location of occurrence. While congenital cases, such as Mongolian spots, nevus of Ota, nevus of Ito, and blue nevus, are common, acquired cases also occur. Acquired bilateral nevus of Ota-like macules is relatively common in Asians;however, extrafacial cases, particularly those involving both the face and extremities, are extremely rare. We report the case of a 66-year-old man with symmetric pigmented patches on the scalp, face, shoulders, and dorsa of the hands for 9 months, following the onset of spots on the forehead and nose that progressively spread. Notably, nasal ala pigmentation was confirmed. Histopathological examination revealed scattered melanin-containing dendritic cells in the upper dermis. Based on the clinicopathological findings, he was diagnosed with acquired dermal melanocytosis of the face and extremities, representing a rare case.