1.A Case of Henoch-Schönlein Purpura with Fulminant Complications and Its Long-term Outcome
Dong Hyun LEE ; Eun So LEE ; Jeong HONG ; Kwang Hwa PARK ; Ki Soo PAI
Childhood Kidney Diseases 2019;23(2):128-133
Henoch-Schönlein purpura (HSP) is a systemic vasculitis characterized by purpura, arthritis, abdominal pain, and nephritis. Gastrointestinal involvement can manifest as pain, intussusception, intestinal bleeding, and intestinal perforation. We report a case of fulminant HSP at an age of eight in 1994, with multiple complications of intra-thoracic bleeding, massive intestinal perforation, nephritis, and various skin rashes. The brisk bleeding findings of intestinal on Technetium-99m-labeled red blood cell scan (99mTc RBC scan) were well matched to those of the emergency laparotomy and the resected intestine. The patient's abdominal conditions improved gradually but nodular skin eruptions developed newly apart from improving preexisting lower limb rashes and the urine findings continued abnormal, so skin and kidney biopsy were done for the diagnosis. After cyclosporine therapy, skin eruptions and urine findings returned to normal gradually. On a follow-up after 25 years in 2019, the patient is 33-year-old, healthy without any abnormality on blood chemistries and urine examination.
Abdominal Pain
;
Adult
;
Arthritis
;
Biopsy
;
Cyclosporine
;
Diagnosis
;
Emergencies
;
Erythrocytes
;
Exanthema
;
Follow-Up Studies
;
Hemorrhage
;
Humans
;
Intestinal Perforation
;
Intestines
;
Intussusception
;
Kidney
;
Laparotomy
;
Lower Extremity
;
Nephritis
;
Purpura
;
Skin
;
Systemic Vasculitis
2.Identifying Predictive Factors for the Recurrence of Pediatric Intussusception
Dong Hyun LEE ; Se Jin KIM ; Hee Jung LEE ; Hyo Jeong JANG
Pediatric Gastroenterology, Hepatology & Nutrition 2019;22(2):142-151
PURPOSE: The aim of the study was to identify factors related to the recurrence of intussusception in pediatric patients. METHODS: The medical charts of patients diagnosed with intussusception and treated at Dongsan Medical Center, between March 2015 to June 2017, were retrospectively reviewed. Univariate and multivariate analyses were performed. RESULTS: Among 137 patients, 23 patients (16.8%) had a recurrent intussusception and 8 of these patients (6%) had more than 2 episodes of recurrence. The age at diagnosis was significantly different between the non-recurrence and recurrence group (p=0.026), with age >1 year at the time of diagnosis associated with a greater rate of recurrence (p=0.002). The time interval from symptom onset to the initial reduction ( < 48 vs. ≥48 hours) was significantly longer in the recurrence group (p=0.034) and patients in the recurrence group had higher levels of C-reactive protein (CRP) (p=0.024). Bloody stools and a history of infection were significantly more frequent in the non-recurrence group (p=0.001 and p < 0.001, respectively). On stepwise regression analysis, age >1 year at the time of presentation (odds ratio [OR], 4.79; 95% confidence interval [CI], 1.56–14.06; p=0.016) and no history of infection (OR, 0.18; 95% CI, 0.06–0.58; p=0.004) were retained as predictors of recurrence. CONCLUSION: Patients with intussusception who are older than 1 year at diagnosis, have an elevated CRP level, a delay of ≥48 hours between symptom onset and the initial reduction, an absence of bloody stools, and no history of infection should be closely monitoring for symptoms and signs of a possible recurrence.
C-Reactive Protein
;
Diagnosis
;
Humans
;
Intussusception
;
Multivariate Analysis
;
Pediatrics
;
Recurrence
;
Retrospective Studies
;
Risk Factors
3.Rapidly Progressive Small Bowel Necrosis in a Previously Healthy Child without Proven Mechanical Obstruction
Hyun Hee KIM ; Hyungoo KANG ; Chul Hee PARK ; Yu Jin KWON ; Euna JUNG ; Misun LIM
Pediatric Gastroenterology, Hepatology & Nutrition 2019;22(3):291-297
Bowel ischemia is a life-threatening surgical emergency. We report a case of rapidly progressive bowel necrosis in a previously healthy child without proven mechanical small bowel obstruction. The definite diagnosis was established at the time of an exploratory operation. Of note, imaging studies and even a laparotomy did not reveal any evidence of acute appendicitis or mechanical obstruction such as intussusception or Meckel's diverticulum. During hospitalization, since we could not rule out surgical abdomen after inconclusive image findings, we closely followed the patient and repeated physical examinations carefully. Eventually surgical exploration was performed based on changes in clinical condition, which proved to be the right decision for the patient. We propose that in children with suspected strangulation of small bowel obstruction, especially when imaging findings do not provide a conclusive diagnosis, the timely exploratory surgical approach ought to be chosen based on carefully observed clinical findings and other evaluations.
Abdomen
;
Appendicitis
;
Child
;
Diagnosis
;
Emergencies
;
Hospitalization
;
Humans
;
Intestine, Small
;
Intussusception
;
Ischemia
;
Laparotomy
;
Meckel Diverticulum
;
Mesenteric Ischemia
;
Necrosis
;
Physical Examination
4.Update on the Pathophysiology and Management of Anorectal Disorders.
Tanisa PATCHARATRAKUL ; Satish S C RAO
Gut and Liver 2018;12(4):375-384
Anorectal disorders are common and present with overlapping symptoms. They include several disorders with both structural and functional dysfunction(s). Because symptoms alone are poor predictors of the underlying pathophysiology, a diagnosis should only be made after evaluating symptoms and physiologic and structural abnormalities. A detailed history, a thorough physical and digital rectal examination and a systematic evaluation with high resolution and/or high definition three-dimensional (3D) anorectal manometry, 3D anal ultrasonography, magnetic resonance defecography and neurophysiology tests are essential to correctly identify these conditions. These physiological and imaging tests play a key role in facilitating a precise diagnosis and in providing a better understanding of the pathophysiology and functional anatomy. In turn, this leads to better and more comprehensive management using medical, behavioral and surgical approaches. For example, patients presenting with difficult defecation may demonstrate dyssynergic defecation and will benefit from biofeedback therapy before considering surgical treatment of coexisting anomalies such as rectoceles or intussusception. Similarly, patients with significant rectal prolapse and pelvic floor dysfunction or patients with complex enteroceles and pelvic organ prolapse may benefit from combined behavioral and surgical approaches, including an open, laparoscopic, transabdominal or transanal, and/or robotic-assisted surgery. Here, we provide an update on the pathophysiology, diagnosis, and management of selected common anorectal disorders.
Biofeedback, Psychology
;
Constipation
;
Defecation
;
Defecography
;
Diagnosis
;
Digital Rectal Examination
;
Humans
;
Intussusception
;
Manometry
;
Neurophysiology
;
Pelvic Floor
;
Pelvic Organ Prolapse
;
Rectal Diseases
;
Rectal Prolapse
;
Rectocele
;
Ultrasonography
5.Tension pneumoperitoneum during pneumatic reduction of pediatric intussusception: case report.
Mi Jin KIM ; Dong Bin KIM ; Jung Seok HONG ; Jin Young JEONG
Journal of the Korean Society of Emergency Medicine 2018;29(4):385-389
This paper presents a case report of tension pneumoperitoneum that occurred in a 4-month-old girl with intussusception during pneumatic reduction. Tension pneumoperitoneum is a rare but life threatening complication in air pressure enema that is commonly used to turn the intussuscepted bowel to its original position. The incidence of a simple pneumoperitoneum due to a bowel perforation associated with attempted pneumatic reduction for intussusception is as high as 4%. The simple pneumoperitoneum changed rapidly to tension pneumoperitoneum and immediate needle decompression was life-saving in this case. Similar to a tension pneumothorax, the diagnosis is clinical and management should not be delayed awaiting other confirmatory tests. The emergency physician must recognize this rare complication of pneumatic reduction and promptly treat the ensuing tension pneumoperitoneum after bowel perforation with immediate needle decompression as a part of the initial resuscitation.
Air Pressure
;
Decompression
;
Diagnosis
;
Emergencies
;
Enema
;
Female
;
Humans
;
Incidence
;
Infant
;
Intussusception*
;
Needles
;
Pneumoperitoneum*
;
Pneumothorax
;
Resuscitation
6.Gastrointestinal Involvement of Recurrent Renal Cell Carcinoma: CT Findings and Clinicopathologic Features.
Hyo Jung PARK ; Hyun Jin KIM ; Seong Ho PARK ; Jong Seok LEE ; Ah Young KIM ; Hyun Kwon HA
Korean Journal of Radiology 2017;18(3):452-460
OBJECTIVE: To retrospectively evaluate the CT findings and clinicopathologic features in patients with gastrointestinal (GI) involvement of recurrent renal cell carcinoma (RCC). MATERIALS AND METHODS: The medical records were reviewed for 15 patients with 19 pathologically proven GI tract metastases of RCC. The CT findings were analyzed to determine the involved sites and type of involvement; lesion size, morphology, and contrast enhancement pattern; and occurrence of lymphadenopathy, ascites and other complications. RESULTS: The most common presentation was GI bleeding (66.7%). The average interval between nephrectomy and the detection of GI involvement was 30.4 ± 37.4 months. GI lesions were most commonly found in the ileum (36.8%) and duodenum (31.6%). A distant metastasis (80%) was more common than a direct invasion from metastatic lesions. The mean lesion size was 34.1 ± 15.0 mm. Intraluminal polypoid masses (63.2%) with hyperenhancement (78.9%) and heterogeneous enhancement (63.2%) were the most common findings. No patients had regional lymphadenopathy. Complications occurred in four patients, with one each of bowel obstruction, intussusception, bile duct dilatation, and pancreatic duct dilatation. CONCLUSION: GI involvement of recurrent RCC could be included in the differential diagnosis of patients with heterogeneous, hyperenhanced intraluminal polypoid masses in the small bowel on CT scans along with a relative paucity of lymphadenopathy.
Ascites
;
Bile Ducts
;
Carcinoma, Renal Cell*
;
Diagnosis, Differential
;
Dilatation
;
Duodenum
;
Gastrointestinal Tract
;
Hemorrhage
;
Humans
;
Ileum
;
Intussusception
;
Lymphatic Diseases
;
Medical Records
;
Neoplasm Metastasis
;
Nephrectomy
;
Pancreatic Ducts
;
Retrospective Studies
;
Tomography, X-Ray Computed
7.Henoch-Schönlein Purpura Presenting as Intussusception.
The Korean Journal of Gastroenterology 2017;69(6):372-376
Henoch-Schönlein purpura (HSP) is systemic vasculitis disease with various clinical manifestations. Gastrointestinal symptoms in patients with HSP are usually common, with an incidence rate of 62-90%. Most of these gastrointestinal symptoms occur after typical skin purpura, which is a very important clinical evidence for making a diagnosis of HSP. It is difficult to diagnose HSP without skin rash. About 25% of patients may experience gastrointestinal symptoms as their first symptoms. Herein, we report a case of ileo-colic intussusception associated with HSP in a 5-years-old girl presented with diffuse abdominal distension. Our patient did present any symptoms of HSP, such as purpura, arthralgia or arthritis, before surgery.
Arthralgia
;
Arthritis
;
Diagnosis
;
Exanthema
;
Female
;
Humans
;
Ileus
;
Incidence
;
Intussusception*
;
Purpura*
;
Purpura, Schoenlein-Henoch
;
Skin
;
Systemic Vasculitis
8.Endoscopic Treatment of Jejunal Heterotopic Gastric Mucosa that Caused Recurrent Intussusception.
Ke Ryun AHN ; Ja Seol KOO ; Hwan Il KIM ; Ji Hye KIM ; Jee Hyun LEE ; Seung Young KIM ; Sung Woo JUNG ; Sang Woo LEE
Clinical Endoscopy 2017;50(6):605-608
Heterotopic gastric mucosa (HGM) is a rare anomaly in the small bowel and may be the cause of intussusception when it gets a lead point in the jejunum. All cases of intussusception due to intestinal HGM have been treated with surgical resection. A 5-year-old girl presented with chief complaints of vomiting and abdominal pain for 2 weeks. A computed tomography scan of the abdomen showed intussusception at the proximal jejunal loops. Three air reductions and one saline reduction were attempted without success. She continued to be symptomatic, and endoscopic evaluation was performed. Enteroscopy revealed some variable-sized polypoid mucosal lesions with erosions on the proximal jejunum. Endoscopic mucosal resection was performed using a snare. The resected tissues histologically showed a hyperplastic polyp arising from the HGM. Her symptoms did not recur within 1 year after the treatment. Our case showed that enteroscopy could be useful for the diagnosis and management of jejunal intussusception caused by HGM.
Abdomen
;
Abdominal Pain
;
Child, Preschool
;
Diagnosis
;
Female
;
Gastric Mucosa*
;
Humans
;
Intussusception*
;
Jejunum
;
Polyps
;
SNARE Proteins
;
Vomiting
9.Giant Duplication Cyst Presenting as a Discharging Umbilicus.
Ravi Kumar GARG ; Monika BAWA ; Katragadda Lakshmi NARASIMHA RAO
Pediatric Gastroenterology, Hepatology & Nutrition 2017;20(3):194-197
Alimentary tract duplication cysts are rare congenital anomalies, most commonly located in the ileum, but may present anywhere from mouth to anus.Clinically, they may be asymptomatic, incidentally diagnosed or may present with obstruction, volvulus, intussusception or gastrointestinal bleed. Here we report a case of a one year old male child presenting in gasping state and shock. Despite the initial strong suspicion of Meckel's diverticulum and tubercular abdomen, the final diagnosis remained elusive till exploratory laparotomy was performed which revealed a duplication cyst of ileum with perforation into the umbilicus. Duplication cyst should always be kept as a differential diagnosis so that early intervention can help in better management.
Abdomen
;
Ascites
;
Child
;
Diagnosis
;
Diagnosis, Differential
;
Early Intervention (Education)
;
Humans
;
Ileum
;
Intestinal Volvulus
;
Intussusception
;
Laparotomy
;
Male
;
Meckel Diverticulum
;
Mouth
;
Shock
;
Umbilicus*
10.Small Bowel Obstruction Caused by Aloe vera Bezoars: A Case Report.
In Taik HONG ; Jae Myung CHA ; Hye Jin KI ; Min Seob KWAK ; Jin Young YOON ; Hyun Phil SHIN ; Jung Won JEOUN ; Sung Il CHOI
The Korean Journal of Gastroenterology 2017;69(5):312-315
Small bowel obstruction is a clinical condition commonly caused by postoperative adhesion, volvulus, intussusceptions, and hernia. Small bowel obstruction due to bezoars is clinically uncommon, accounting for approximately 2-4% of all obstructions. Computed tomography (CT) is a useful method in diagnosing the cause of small bowel obstruction. However, small bowel obstruction caused by bezoars may not be detected by an abdominal CT examination. Herein, we report a rare case of small bowel obstruction by Aloe vera bezoars, which were undetected by an abdominal CT. Phytobezoars should be included in the differential diagnosis of small bowel obstruction in patients with predisposing factors, such as excessive consumption of high-fiber food and diabetes.
Aloe*
;
Bezoars*
;
Causality
;
Diagnosis, Differential
;
Hernia
;
Humans
;
Intestinal Obstruction
;
Intestinal Volvulus
;
Intestine, Small
;
Intussusception
;
Methods
;
Tomography, X-Ray Computed

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